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Iqbal S. Grewal
Iqbal S. Grewal
Global Head of Immunotherapeutics, Janssen R&D
Email verificata su its.jnj.com
Titolo
Citata da
Citata da
Anno
CD40 and CD154 in cell-mediated immunity
IS Grewal, RA Flavell
Annual review of immunology 16 (1), 111-135, 1998
21281998
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2
N Kayagaki, M Yan, D Seshasayee, H Wang, W Lee, DM French, ...
Immunity 17 (4), 515-524, 2002
6102002
Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
IS Grewal, J Xu, RA Flavell
Nature 378 (6557), 617-620, 1995
5971995
The role of CD40 ligand in costimulation and T-cell activation.
IS Grewal, RA Flavell
Immunological reviews 153, 85-106, 1996
5871996
Requirement for CD154 in the progression of atherosclerosis
E Lutgens, L Gorelik, MJAP Daemen, ED De Muinck, IS Grewal, ...
Nature medicine 5 (11), 1313-1316, 1999
5661999
Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis
IS Grewal, HG Foellmer, KD Grewal, J Xu, F Hardardottir, JL Baron, ...
Science 273 (5283), 1864-1867, 1996
5161996
Activation and accumulation of B cells in TACI-deficient mice
M Yan, H Wang, B Chan, M Roose-Girma, S Erickson, T Baker, D Tumas, ...
Nature immunology 2 (7), 638-643, 2001
5142001
Development of Th1-type immune responses requires the type I cytokine receptor TCCR
QI Chen, N Ghilardi, H Wang, T Baker, MH Xie, A Gurney, IS Grewal, ...
Nature 407 (6806), 916-920, 2000
5052000
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
M Yan, JR Brady, B Chan, WP Lee, B Hsu, S Harless, M Cancro, ...
Current Biology 11 (19), 1547-1552, 2001
5042001
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
D Seshasayee, P Valdez, M Yan, VM Dixit, D Tumas, IS Grewal
Immunity 18 (2), 279-288, 2003
5032003
A central role of CD40 ligand in the regulation of CD4+ T-cell responses
IS Grewal, RA Flavell
Immunology today 17 (9), 410-414, 1996
3941996
Disruption of CD40–CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection
L Soong, JC Xu, IS Grewal, P Kima, J Sun, BJ Longley, NH Ruddle, ...
Immunity 4 (3), 263-273, 1996
3731996
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.
P Borrow, A Tishon, S Lee, J Xu, IS Grewal, MB Oldstone, RA Flavell
The Journal of experimental medicine 183 (5), 2129-2142, 1996
3541996
Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice.
RD Stout, J Suttles, J Xu, IS Grewal, RA Flavell
Journal of immunology (Baltimore, Md.: 1950) 156 (1), 8-11, 1996
3081996
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
M Yan, SA Marsters, IS Grewal, H Wang, A Ashkenazi, VM Dixit
Nature immunology 1 (1), 37-41, 2000
2982000
TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice
H Wang, SA Marsters, T Baker, B Chan, WP Lee, L Fu, D Tumas, M Yan, ...
Nature immunology 2 (7), 632-637, 2001
2622001
APRIL-deficient mice have normal immune system development
E Varfolomeev, F Kischkel, F Martin, D Seshasayee, H Wang, D Lawrence, ...
Molecular and cellular biology 24 (3), 997-1006, 2004
2222004
Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40–induced cytotoxicity in human multiple myeloma: clinical implications
YT Tai, XF Li, L Catley, R Coffey, I Breitkreutz, J Bae, W Song, K Podar, ...
Cancer research 65 (24), 11712-11720, 2005
2122005
Transgenic monocyte chemoattractant protein-1 (MCP-1) in pancreatic islets produces monocyte-rich insulitis without diabetes: abrogation by a second transgene expressing …
IS Grewal, BJ Rutledge, JA Fiorillo, L Gu, RP Gladue, RA Flavell, ...
Journal of immunology (Baltimore, Md.: 1950) 159 (1), 401-408, 1997
2121997
Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
Y Yang, Q Su, IS Grewal, R Schilz, RA Flavell, JM Wilson
Journal of virology 70 (9), 6370-6377, 1996
2111996
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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