Dante Rotili, PhD
Dante Rotili, PhD
Assistant Professor of Medicinal Chemistry, University of Rome "La Sapienza"
Verified email at uniroma1.it
Title
Cited by
Cited by
Year
Histone deacetylation in epigenetics: an attractive target for anticancer therapy
A Mai, S Massa, D Rotili, I Cerbara, S Valente, R Pezzi, S Simeoni, ...
Medicinal research reviews 25 (3), 261-309, 2005
3552005
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
E Lara, A Mai, V Calvanese, L Altucci, P Lopez-Nieva, ...
Oncogene 28 (6), 781-791, 2009
2432009
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl) pyrrolyl hydroxyamides
A Mai, S Massa, R Pezzi, S Simeoni, D Rotili, A Nebbioso, ...
Journal of medicinal chemistry 48 (9), 3344-3353, 2005
2042005
Targeting histone demethylases: a new avenue for the fight against cancer
D Rotili, A Mai
Genes & cancer 2 (6), 663-679, 2011
1832011
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue
A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ...
diabetes 62 (3), 732-742, 2013
1532013
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes
A Nebbioso, F Manzo, M Miceli, M Conte, L Manente, A Baldi, A De Luca, ...
EMBO reports 10 (7), 776-782, 2009
1452009
Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties
A Mai, D Rotili, D Tarantino, P Ornaghi, F Tosi, C Vicidomini, G Sbardella, ...
Journal of medicinal chemistry 49 (23), 6897-6907, 2006
1212006
Sirtuin functions and modulation: from chemistry to the clinic
V Carafa, D Rotili, M Forgione, F Cuomo, E Serretiello, GS Hailu, E Jarho, ...
Clinical epigenetics 8 (1), 61, 2016
1162016
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling
B Illi, CD Russo, C Colussi, J Rosati, M Pallaoro, F Spallotta, D Rotili, ...
Circulation research 102 (1), 51-58, 2008
1142008
" Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line modelsá…
A Savarino, A Mai, S Norelli, S El Daker, S Valente, D Rotili, L Altucci, ...
Retrovirology 6 (1), 1-10, 2009
1112009
SIRT5 regulation of ammonia-induced autophagy and mitophagy
L Polletta, E Vernucci, I Carnevale, T Arcangeli, D Rotili, S Palmerio, ...
Autophagy 11 (2), 253-270, 2015
1072015
Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases
G Sbardella, S Castellano, C Vicidomini, D Rotili, A Nebbioso, M Miceli, ...
Bioorganic & medicinal chemistry letters 18 (9), 2788-2792, 2008
972008
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
942014
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
A Mai, D Rotili, S Massa, G Brosch, G Simonetti, C Passariello, ...
Bioorganic & Medicinal Chemistry Letters 17 (5), 1221-1225, 2007
902007
p300/CBP-associated factor selectively regulates the extinction of conditioned fear
W Wei, CM Coelho, X Li, R Marek, S Yan, S Anderson, D Meyers, ...
Journal of Neuroscience 32 (35), 11930-11941, 2012
822012
Synthesis and biological properties of novel 2-aminopyrimidin-4 (3 H)-ones highly potent against HIV-1 mutant strains
A Mai, M Artico, D Rotili, D Tarantino, I Clotet-Codina, M Armand-Ugˇn, ...
Journal of medicinal chemistry 50 (22), 5412-5424, 2007
782007
Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise
A Mai, D Rotili, S Valente, AG Kazantsev
Current pharmaceutical design 15 (34), 3940-3957, 2009
742009
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a Series of Anti-HIV-1 Agents of the Dihydro-alkoxy-benzyl-oxopyrimidine Family withá…
MB Nawrozkij, D Rotili, D Tarantino, G Botta, AS Eremiychuk, I Musmuca, ...
Journal of medicinal chemistry 51 (15), 4641-4652, 2008
732008
Discovery of (aryloxopropenyl) pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A
A Mai, S Massa, R Pezzi, D Rotili, P Loidl, G Brosch
Journal of medicinal chemistry 46 (23), 4826-4829, 2003
732003
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells
D Rotili, D Tarantino, A Nebbioso, C Paolini, C Huidobro, E Lara, P Mellini, ...
Journal of medicinal chemistry 55 (24), 10937-10947, 2012
672012
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