Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 458 | 2010 |
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials MV Holmes, P Newcombe, JA Hubacek, R Sofat, SL Ricketts, J Cooper, ... The Lancet 378 (9791), 584-594, 2011 | 421 | 2011 |
Early infection with Trichuris trichiura and allergen skin test reactivity in later childhood LC Rodrigues, PJ Newcombe, SS Cunha, NM Alcantara‐Neves, ... Clinical & Experimental Allergy 38 (11), 1769-1777, 2008 | 168 | 2008 |
Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial AK Kader, J Sun, BH Reck, PJ Newcombe, ST Kim, FC Hsu, ... European urology 62 (6), 953-961, 2012 | 106 | 2012 |
Insight into genotype-phenotype associations through eQTL mapping in multiple cell types in health and immune-mediated disease JE Peters, PA Lyons, JC Lee, AC Richard, MD Fortune, PJ Newcombe, ... PLoS genetics 12 (3), e1005908, 2016 | 101 | 2016 |
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants T Dadaev, EJ Saunders, PJ Newcombe, E Anokian, DA Leongamornlert, ... Nature communications 9 (1), 2256, 2018 | 100 | 2018 |
Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction T Shah, P Newcombe, L Smeeth, J Addo, JP Casas, J Whittaker, ... Circulation: Cardiovascular Genetics 3 (5), 436-444, 2010 | 90 | 2010 |
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis K Chan, RS Patel, P Newcombe, CP Nelson, A Qasim, SE Epstein, ... Journal of the American College of Cardiology 61 (9), 957-970, 2013 | 81 | 2013 |
JAM: a scalable Bayesian framework for joint analysis of marginal SNP effects PJ Newcombe, DV Conti, S Richardson Genetic epidemiology 40 (3), 188-201, 2016 | 79 | 2016 |
GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm L Bottolo, M Chadeau-Hyam, DI Hastie, T Zeller, B Liquet, P Newcombe, ... PLoS genetics 9 (8), e1003657, 2013 | 66 | 2013 |
Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1* 07: 01 LR Parham, LP Briley, L Li, J Shen, PJ Newcombe, KS King, AJ Slater, ... The pharmacogenomics journal 16 (2), 180-185, 2016 | 63 | 2016 |
Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine R Liu, C Chen, X Xia, Q Liao, Q Wang, PJ Newcombe, S Xu, M Chen, ... Scientific Reports 7 (1), 9214, 2017 | 49 | 2017 |
Genetic factors associated with response to intravitreal ranibizumab in Korean patients with neovascular age-related macular degeneration UC Park, JY Shin, SJ Kim, ES Shin, JE Lee, LC McCarthy, PJ Newcombe, ... Retina 34 (2), 288-297, 2014 | 48 | 2014 |
In severe alcoholic hepatitis, serum keratin-18 fragments are diagnostic, prognostic, and theragnostic biomarkers SR Atkinson, JI Grove, S Liebig, S Astbury, N Vergis, R Goldin, A Quaglia, ... Official journal of the American College of Gastroenterology| ACG 115 (11 …, 2020 | 47 | 2020 |
A flexible and parallelizable approach to genome‐wide polygenic risk scores PJ Newcombe, CP Nelson, NJ Samani, F Dudbridge Genetic epidemiology 43 (7), 730-741, 2019 | 40 | 2019 |
Weibull regression with Bayesian variable selection to identify prognostic tumour markers of breast cancer survival PJ Newcombe, H Raza Ali, FM Blows, E Provenzano, PD Pharoah, ... Statistical methods in medical research 26 (1), 414-436, 2017 | 37 | 2017 |
Multilocus Bayesian meta-analysis of gene-disease associations PJ Newcombe, C Verzilli, JP Casas, AD Hingorani, L Smeeth, ... The American Journal of Human Genetics 84 (5), 567-580, 2009 | 33 | 2009 |
Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data A Gkatzionis, S Burgess, PJ Newcombe Genetic epidemiology 47 (1), 3-25, 2023 | 32 | 2023 |
Accuracy of gene scores when pruning markers by linkage disequilibrium F Dudbridge, PJ Newcombe Human heredity 80 (4), 178-186, 2016 | 23 | 2016 |
Fine mapping chromatin contacts in capture Hi-C data CQ Eijsbouts, OS Burren, PJ Newcombe, C Wallace BMC genomics 20, 1-13, 2019 | 21 | 2019 |