In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases JI Diaz-Hernandez, R Gomez-Villafuertes, M León-Otegui, ... Neurobiology of aging 33 (8), 1816-1828, 2012 | 214 | 2012 |
Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons M Díaz-Hernandez, A del Puerto, JI Díaz-Hernandez, M Diez-Zaera, ... Journal of cell science 121 (22), 3717-3728, 2008 | 170 | 2008 |
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing A Parras, H Anta, M Santos-Galindo, V Swarup, A Elorza, ... Nature 560 (7719), 441-446, 2018 | 128 | 2018 |
Characteristics and consequences of muscarinic receptor activation by tau protein A Gómez-Ramos, M Díaz-Hernández, A Rubio, JI Díaz-Hernández, ... European Neuropsychopharmacology 19 (10), 708-717, 2009 | 124 | 2009 |
Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons M Díez-Zaera, JI Díaz-Hernández, E Hernández-Álvarez, H Zimmermann, ... Molecular biology of the cell 22 (7), 1014-1024, 2011 | 120 | 2011 |
Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation A del Puerto, JI Díaz-Hernández, M Tapia, R Gomez-Villafuertes, ... Journal of cell science 125 (1), 176-188, 2012 | 105 | 2012 |
Ca2+/calmodulin‐dependent kinase II signalling cascade mediates P2X7 receptor‐dependent inhibition of neuritogenesis in neuroblastoma cells R Gómez‐Villafuertes, A del Puerto, M Díaz‐Hernández, D Bustillo, ... The FEBS journal 276 (18), 5307-5325, 2009 | 95 | 2009 |
Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons JI Diaz-Hernandez, A Almeida, M Delgado-Esteban, E Fernandez, ... Journal of Biological Chemistry 280 (47), 38992-39001, 2005 | 91 | 2005 |
PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions R Gómez-Villafuertes, P García-Huerta, JI Díaz-Hernández, ... Scientific reports 5 (1), 18417, 2015 | 81 | 2015 |
Nucleotides in neuroregeneration and neuroprotection MT Miras-Portugal, R Gomez-Villafuertes, J Gualix, JI Diaz-Hernandez, ... Neuropharmacology 104, 243-254, 2016 | 74 | 2016 |
Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells M León-Otegui, R Gómez-Villafuertes, JI Díaz-Hernández, ... FEBS letters 585 (14), 2255-2262, 2011 | 70 | 2011 |
TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic … M Fakhry, M Roszkowska, A Briolay, C Bougault, A Guignandon, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (3), 643-653, 2017 | 59 | 2017 |
Poly (ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress JI Diaz-Hernandez, S Moncada, JP Bolaños, A Almeida Cell Death & Differentiation 14 (6), 1211-1221, 2007 | 52 | 2007 |
Increased levels of extracellular ATP in glaucomatous retinas: possible role of the vesicular nucleotide transporter during the development of the pathology MJP de Lara, A Guzmán-Aránguez, P de la Villa, JI Díaz-Hernández, ... Molecular vision 21, 1060, 2015 | 41 | 2015 |
Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation “in vivo” by P2X7 receptor MT Miras-Portugal, JI Diaz-Hernandez, R Gomez-Villafuertes, ... Computational and structural biotechnology journal 13, 176-181, 2015 | 39 | 2015 |
Huntington’s disease-specific mis-splicing unveils key effector genes and altered splicing factors A Elorza, Y Márquez, JR Cabrera, JL Sánchez-Trincado, ... Brain 144 (7), 2009-2023, 2021 | 29 | 2021 |
Specific temporal distribution and subcellular localization of a functional vesicular nucleotide transporter (VNUT) in cerebellar granule neurons A Menéndez-Méndez, JI Díaz-Hernández, F Ortega, J Gualix, ... Frontiers in Pharmacology 8, 324345, 2017 | 21 | 2017 |
The vesicular nucleotide transporter (VNUT) is involved in the extracellular ATP effect on neuronal differentiation A Menéndez-Méndez, JI Díaz-Hernández, MT Miras-Portugal Purinergic Signalling 11, 239-249, 2015 | 20 | 2015 |
Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1 JI Díaz-Hernández, Á Sebastián-Serrano, R Gómez-Villafuertes, ... PloS one 10 (4), e0123121, 2015 | 12 | 2015 |
RT-MODULA2: An embedded in MODULA2 language for writing concurrent and real time programs J Hernandez, JA Sanchez ACM SIGPLAN Notices 27 (2), 26-36, 1992 | 9 | 1992 |