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Guanghui Yang
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An atomic structure of human γ-secretase
X Bai, C Yan, G Yang, P Lu, D Ma, L Sun, R Zhou, SHW Scheres, Y Shi
Nature 525 (7568), 212-217, 2015
5842015
Sampling the conformational space of the catalytic subunit of human γ-secretase
X Bai, E Rajendra, G Yang, Y Shi, SHW Scheres
elife 4, e11182, 2015
5792015
Three-dimensional structure of human γ-secretase
P Lu, X Bai, D Ma, T Xie, C Yan, L Sun, G Yang, Y Zhao, R Zhou, ...
Nature 512 (7513), 166-170, 2014
4122014
Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase
L Sun, R Zhou, G Yang, Y Shi
Proceedings of the National Academy of Sciences 114 (4), E476-E485, 2017
3542017
Recognition of the amyloid precursor protein by human γ-secretase
R Zhou, G Yang, X Guo, Q Zhou, J Lei, Y Shi
Science 363 (6428), eaaw0930, 2019
2962019
Structural basis of Notch recognition by human γ-secretase
G Yang, R Zhou, Q Zhou, X Guo, C Yan, M Ke, J Lei, Y Shi
Nature 565 (7738), 192-197, 2019
2362019
Structural basis of human γ-secretase assembly
L Sun, L Zhao, G Yang, C Yan, R Zhou, X Zhou, T Xie, Y Zhao, S Wu, X Li, ...
Proceedings of the National Academy of Sciences 112 (19), 6003-6008, 2015
1282015
Structural basis of γ-secretase inhibition and modulation by small molecule drugs
G Yang, R Zhou, X Guo, C Yan, J Lei, Y Shi
Cell 184 (2), 521-533. e14, 2021
1142021
Dimeric structure of the uracil: proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters
X Yu, G Yang, C Yan, JL Baylon, J Jiang, H Fan, G Lu, K Hasegawa, ...
Cell research 27 (8), 1020-1033, 2017
992017
Crystal structure of the γ-secretase component nicastrin
T Xie, C Yan, R Zhou, Y Zhao, L Sun, G Yang, P Lu, D Ma, Y Shi
Proceedings of the National Academy of Sciences 111 (37), 13349-13354, 2014
832014
Dominant negative effect of the loss-of-function γ-secretase mutants on the wild-type enzyme through heterooligomerization
R Zhou, G Yang, Y Shi
Proceedings of the National Academy of Sciences 114 (48), 12731-12736, 2017
532017
Cryo-EM structures of human γ-secretase
G Yang, R Zhou, Y Shi
Current Opinion in Structural Biology 46, 55-64, 2017
282017
Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis
Y Lu, M Yu, Y Jia, F Yang, Y Zhang, X Xu, X Li, F Yang, J Lei, Y Wang, ...
Nature Communications 13 (1), 5682, 2022
182022
Macromolecular complex in recognition and proteolysis of amyloid precursor protein in Alzheimer’s disease
R Zhou, G Yang, Y Shi
Current Opinion in Structural Biology 61, 1-8, 2020
182020
Modulation of amyloid precursor protein cleavage by γ-secretase activating protein through phase separation
C Jin, J Wang, Y Wang, B Jia, X Guo, G Yang, P Xu, P Greengard, R Zhou, ...
Proceedings of the National Academy of Sciences 119 (12), e2122292119, 2022
72022
Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance
Y Zhang, J Zhou, X Ni, Q Wang, Y Jia, X Xu, H Wu, P Fu, H Wen, Y Guo, ...
Nature Plants 9 (11), 1915-1923, 2023
42023
Expression, purification, and enzymatic characterization of intramembrane proteases
R Zhou, Y Shi, G Yang
Methods in Enzymology 584, 127-155, 2017
32017
Structural and functional insights of the human peroxisomal ABC transporter ALDP
Y Jia, Y Zhang, W Wang, J Lei, Z Ying, G Yang
Elife 11, e75039, 2022
12022
Structure insights of the human peroxisomal ABC transporter ALDP
Y Jia, Y Zhang, J Lei, G Yang
bioRxiv, 2021.09. 24.461756, 2021
12021
Structural insights into the Oryza sativa cation transporters HKTs in salt tolerance
R Gao, Y Jia, X Xu, P Fu, J Zhou, G Yang
Journal of Integrative Plant Biology, 2024
2024
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