| Epigenetics in cancer M Esteller New England Journal of Medicine 358 (11), 1148-1159, 2008 | 3885 | 2008 |
| Epigenetic differences arise during the lifetime of monozygotic twins MF Fraga, E Ballestar, MF Paz, S Ropero, F Setien, ML Ballestar, ... Proceedings of the National Academy of Sciences 102 (30), 10604-10609, 2005 | 3681 | 2005 |
| Non-coding RNAs in human disease M Esteller Nature reviews genetics 12 (12), 861-874, 2011 | 3588 | 2011 |
| A gene hypermethylation profile of human cancer M Esteller, PG Corn, SB Baylin, JG Herman Cancer research 61 (8), 3225-3229, 2001 | 2587 | 2001 |
| Epigenetic modifications and human disease A Portela, M Esteller Nature biotechnology 28 (10), 1057, 2010 | 2453 | 2010 |
| Cancer epigenomics: DNA methylomes and histone-modification maps M Esteller Nature reviews genetics 8 (4), 286-298, 2007 | 2359 | 2007 |
| Inactivation of the DNA-Repair Gene MGMT and the Clinical Response of Gliomas to Alkylating Agents M Esteller, J Garcia-Foncillas, E Andion, SN Goodman, OF Hidalgo, ... New England Journal of Medicine 343 (19), 1350-1354, 2000 | 2300 | 2000 |
| The Polycomb group protein EZH2 directly controls DNA methylation E Viré, C Brenner, R Deplus, L Blanchon, M Fraga, C Didelot, L Morey, ... Nature 439 (7078), 871-874, 2006 | 2168 | 2006 |
| New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2053 | 2010 |
| Gene-expression profiles in hereditary breast cancer I Hedenfalk, D Duggan, Y Chen, M Radmacher, M Bittner, R Simon, ... New England Journal of Medicine 344 (8), 539-548, 2001 | 2018 | 2001 |
| Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer MF Fraga, E Ballestar, A Villar-Garea, M Boix-Chornet, J Espada, ... Nature genetics 37 (4), 391-400, 2005 | 1954 | 2005 |
| Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia M Esteller, SR Hamilton, PC Burger, SB Baylin, JG Herman Cancer research 59 (4), 793-797, 1999 | 1414 | 1999 |
| CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future M Esteller Oncogene 21 (35), 5427-5440, 2002 | 1404 | 2002 |
| Global epigenomic reconfiguration during mammalian brain development R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ... Science 341 (6146), 2013 | 1390 | 2013 |
| Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors M Esteller, JM Silva, G Dominguez, F Bonilla, X Matias-Guiu, E Lerma, ... JNCI: Journal of the National Cancer Institute 92 (7), 564-569, 2000 | 1276 | 2000 |
| The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors V Bolós, H Peinado, MA Pérez-Moreno, MF Fraga, M Esteller, A Cano Journal of cell science 116 (3), 499-511, 2003 | 1207 | 2003 |
| Cancer epigenetics reaches mainstream oncology M Rodríguez-Paredes, M Esteller Nature medicine 17 (3), 330-339, 2011 | 1191 | 2011 |
| Inactivation of the apoptosis effector Apaf-1 in malignant melanoma MS Soengas, P Capodieci, D Polsky, J Mora, M Esteller, X Opitz-Araya, ... Nature 409 (6817), 207-211, 2001 | 1173 | 2001 |
| A microRNA DNA methylation signature for human cancer metastasis A Lujambio, GA Calin, A Villanueva, S Ropero, M Sánchez-Céspedes, ... Proceedings of the National Academy of Sciences 105 (36), 13556-13561, 2008 | 1171 | 2008 |
| Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients M Esteller, M Sanchez-Cespedes, R Rosell, D Sidransky, SB Baylin, ... Cancer research 59 (1), 67-70, 1999 | 1171 | 1999 |
