Claudia Manzoni
Claudia Manzoni
University of Reading
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Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein
C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ...
Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis
G Di Fede, M Catania, M Morbin, G Rossi, S Suardi, G Mazzoleni, ...
Science 323 (5920), 1473-1477, 2009
The SIRT1 activator resveratrol protects SK‐N‐BE cells from oxidative stress and against toxicity caused by α‐synuclein or amyloid‐β (1‐42) peptide
D Albani, L Polito, S Batelli, S De Mauro, C Fracasso, G Martelli, ...
Journal of neurochemistry 110 (5), 1445-1456, 2009
Inhibition of LRRK2 kinase activity stimulates macroautophagy
C Manzoni, A Mamais, S Dihanich, R Abeti, MPM Soutar, H Plun-Favreau, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2900-2910, 2013
Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
C Manzoni, A Mamais, S Dihanich, P McGoldrick, MJ Devine, J Zerle, ...
Biochemical and biophysical research communications 441 (4), 862-866, 2013
LRRK2 and human disease: a complicated question or a question of complexes?
PA Lewis, C Manzoni
Science Signaling 5 (207), pe2, 2012
Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies
C Manzoni, PA Lewis
The FASEB Journal 27 (9), 3424-3429, 2013
Conformational plasticity of the Gerstmann–Sträussler–Scheinker disease peptide as indicated by its multiple aggregation pathways
A Natalello, VV Prokorov, F Tagliavini, M Morbin, G Forloni, M Beeg, ...
Journal of molecular biology 381 (5), 1349-1361, 2008
Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction
C Airoldi, L Colombo, C Manzoni, E Sironi, A Natalello, SM Doglia, ...
Organic & biomolecular chemistry 9 (2), 463-472, 2011
Overcoming synthetic Aβ peptide aging: a new approach to an age-old problem
C Manzoni, L Colombo, M Messa, A Cagnotto, L Cantu, E Del Favero, ...
Amyloid 16 (2), 71-80, 2009
The molecular assembly of amyloid Aβ controls its neurotoxicity and binding to cellular proteins
C Manzoni, L Colombo, P Bigini, V Diana, A Cagnotto, M Messa, M Lupi, ...
PloS one 6 (9), e24909, 2011
Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the “dock-and-lock” model
M Gobbi, L Colombo, M Morbin, G Mazzoleni, E Accardo, M Vanoni, ...
Journal of Biological Chemistry 281 (2), 843-849, 2006
Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann–Sträussler–Scheinker disease amyloid protein
L Fioriti, N Angeretti, L Colombo, A De Luigi, A Colombo, C Manzoni, ...
The Journal of neuroscience 27 (7), 1576-1583, 2007
Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases
A Mamais, M Raja, C Manzoni, S Dihanich, A Lees, D Moore, PA Lewis, ...
Neurobiology of disease 58, 183-190, 2013
Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue.
MJ Devine, A Kaganovich, M Ryten, A Mamais, D Trabzuni, C Manzoni, ...
PloS one 7 (1), 2012
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue
MJ Devine, A Kaganovich, M Ryten, A Mamais, D Trabzuni, C Manzoni, ...
PloS one 6 (7), e22489, 2011
Acetylcholinesterase triggers the aggregation of PrP 106–126
M Pera, S Roman, M Ratia, P Camps, D Munoz-Torrero, L Colombo, ...
Biochemical and biophysical research communications 346 (1), 89-94, 2006
LRRK2 and autophagy: a common pathway for disease.
C Manzoni
Biochemical Society Transactions 40 (5), 2012
GTP binding controls complex formation by the human ROCO protein MASL1
S Dihanich, L Civiero, C Manzoni, A Mamais, R Bandopadhyay, ...
FEBS Journal 281 (1), 261-274, 2014
Rare variants in LRRK1 and Parkinson's disease
EC Schulte, DC Ellwanger, S Dihanich, C Manzoni, K Stangl, B Schormair, ...
neurogenetics, 1-9, 2013
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