Stephen Holman
Stephen Holman
Associate Principal Scientist, AstraZeneca
Verified email at
Cited by
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The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics
F Lanucara, SW Holman, CJ Gray, CE Eyers
Nature Chemistry 6 (4), 281-294, 2014
Global absolute quantification of a proteome: Challenges in the deployment of a QconCAT strategy
P Brownridge, SW Holman, SJ Gaskell, CM Grant, VM Harman, ...
Proteomics 11 (15), 2957-2970, 2011
The use of selected reaction monitoring in quantitative proteomics
SW Holman, PFG Sims, CE Eyers
Bioanalysis 4 (14), 1763-1786, 2012
Direct and absolute quantification of over 1800 yeast proteins via selected reaction monitoring
C Lawless, SW Holman, P Brownridge, K Lanthaler, VM Harman, ...
Molecular & Cellular Proteomics 15 (4), 1309-1322, 2016
Quantitative analysis of chaperone network throughput in budding yeast
P Brownridge, C Lawless, AB Payapilly, K Lanthaler, SW Holman, ...
Proteomics 13 (8), 1276-1291, 2013
Analysis of intrinsic peptide detectability via integrated label-free and SRM-based absolute quantitative proteomics
AF Jarnuczak, DCH Lee, C Lawless, SW Holman, CE Eyers, SJ Hubbard
Journal of proteome research 15 (9), 2945-2959, 2016
Absolute protein quantification of the yeast chaperome under conditions of heat shock
RJ Mackenzie, C Lawless, SW Holman, K Lanthaler, RJ Beynon, ...
Proteomics 16 (15-16), 2128-2140, 2016
RePLiCal: a QconCAT protein for retention time standardization in proteomics studies
SW Holman, L McLean, CE Eyers
Journal of Proteome Research 15 (3), 1090-1102, 2016
Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription
F Lanucara, C Lam, J Mann, TP Monie, SAP Colombo, SW Holman, ...
Open biology 6 (7), 160055, 2016
High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 1. Evidence for an ortho effect on the fragmentation of 4 …
SW Holman, P Wright, GJ Langley
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2008
Evaluation of dimethyl sulfoxide (DMSO) as a mobile phase additive during top 3 label-free quantitative proteomics
D Strzelecka, SW Holman, CE Eyers
International journal of mass spectrometry 391, 157-160, 2015
Peptide Scrambling During Collision-Induced Dissociation is Influenced by N-terminal Residue Basicity
R Chawner, SW Holman, SJ Gaskell, CE Eyers
Journal of the American Society for Mass Spectrometry 25 (11), 1927-1938, 2014
A quantitative assessment of the chemical variation in food grade polyethylene cling film, a common wrapping material for illicit drugs, using attenuated total reflection …
SW Holman, TF Emmett, MD Cole
Analytical Methods 4 (6), 1667-1673, 2012
High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 2. An example of how unexpected dissociation behaviour could preclude …
SW Holman, P Wright, GJ Langley
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009
Representation of selected‐reaction monitoring data in the mzQuantML data standard
D Qi, C Lawless, J Teleman, F Levander, SW Holman, S Hubbard, ...
Proteomics 15 (15), 2592-2596, 2015
DOSCATs: Double standards for protein quantification
RJ Bennett, DM Simpson, SW Holman, S Ryan, P Brownridge, CE Eyers, ...
Scientific reports 7, 45570, 2017
Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS)
SW Holman, DE Hammond, DM Simpson, J Waters, JL Hurst, RJ Beynon
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016
A Rapid Methodology for the Characterization of Dialkyl Tertiary Amine-N-Oxide Metabolites Using Structurally Dependent Dissociation Pathways and …
SW Holman, P Wright, GJ Langley
Analytical chemistry 82 (6), 2347-2354, 2010
Evidence for site‐specific intra‐ionic hydrogen/deuterium exchange in the low‐energy collision‐induced dissociation product ion spectra of protonated small molecules generated …
SW Holman, P Wright, NJ Wells, GJ Langley
Journal of mass spectrometry 45 (4), 347-357, 2010
Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1
R Szatkowska, M Garcia-Albornoz, K Roszkowska, SW Holman, ...
Biochemical Journal 476 (7), 1053-1082, 2019
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