Katerina Akassoglou
Katerina Akassoglou
Senior Investigator, Gladstone Institutes; Professor of Neurology, UCSF
Email verificata su gladstone.ucsf.edu
Citata da
Citata da
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
J Rius, M Guma, C Schachtrup, K Akassoglou, AS Zinkernagel, V Nizet, ...
Nature 453 (7196), 807-811, 2008
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ...
Science 339 (6116), 211-214, 2013
Fibrinogen as a key regulator of inflammation in disease
D Davalos, K Akassoglou
Seminars in immunopathology 34 (1), 43-62, 2012
Resolving postoperative neuroinflammation and cognitive decline
N Terrando, LI Eriksson, J Kyu Ryu, T Yang, C Monaco, M Feldmann, ...
Annals of neurology 70 (6), 986-995, 2011
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
L Probert, K Akassoglou, M Pasparakis, G Kontogeorgos, G Kollias
Proceedings of the National Academy of Sciences 92 (24), 11294-11298, 1995
Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple …
K Akassoglou, J Bauer, G Kassiotis, M Pasparakis, H Lassmann, G Kollias, ...
The American journal of pathology 153 (3), 801-813, 1998
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
D Davalos, JK Ryu, M Merlini, KM Baeten, N Le Moan, MA Petersen, ...
Nature communications 3 (1), 1-15, 2012
Chronic optical access through a polished and reinforced thinned skull
PJ Drew, AY Shih, JD Driscoll, PM Knutsen, P Blinder, D Davalos, ...
Nature methods 7 (12), 981-984, 2010
Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.
K Akassoglou, L Probert, G Kontogeorgos, G Kollias
The Journal of Immunology 158 (1), 438-445, 1997
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-β after vascular damage
C Schachtrup, JK Ryu, MJ Helmrick, E Vagena, DK Galanakis, JL Degen, ...
Journal of Neuroscience 30 (17), 5843-5854, 2010
The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease
RA Adams, J Bauer, MJ Flick, SL Sikorski, T Nuriel, H Lassmann, ...
The Journal of experimental medicine 204 (3), 571-582, 2007
Extracellular matrix and matrix receptors in blood–brain barrier formation and stroke
KM Baeten, K Akassoglou
Developmental neurobiology 71 (11), 1018-1039, 2011
Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation
K Akassoglou, WM Yu, P Akpinar, S Strickland
Neuron 33 (6), 861-875, 2002
Tissue plasminogen activator–mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury
K Akassoglou, KW Kombrinck, JL Degen, S Strickland
The Journal of cell biology 149 (5), 1157-1166, 2000
TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease
L Probert, HP Eugster, K Akassoglou, J Bauer, K Frei, H Lassmann, ...
Brain 123 (10), 2005-2019, 2000
TNF-α transgenic and knockout models of CNS inflammation and degeneration
L Probert, K Akassoglou, G Kassiotis, M Pasparakis, L Alexopoulou, ...
Journal of neuroimmunology 72 (2), 137-141, 1997
Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR
MA Passino, RA Adams, SL Sikorski, K Akassoglou
Science 315 (5820), 1853-1856, 2007
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration
K Akassoglou, B Malester, J Xu, L Tessarollo, J Rosenbluth, MV Chao
Proceedings of the National Academy of Sciences 101 (14), 5075-5080, 2004
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
JK Ryu, MA Petersen, SG Murray, KM Baeten, A Meyer-Franke, JP Chan, ...
Nature communications 6 (1), 1-15, 2015
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism
P Gut, B Baeza-Raja, O Andersson, L Hasenkamp, J Hsiao, D Hesselson, ...
Nature chemical biology 9 (2), 97-104, 2013
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