Andrew D. Mesecar
Andrew D. Mesecar
Walther Professor of Structural Biology, Purdue University, Department of Biochemistry
Verified email at purdue.edu
Title
Cited by
Cited by
Year
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
AL Eggler, G Liu, JM Pezzuto, RB Van Breemen, AD Mesecar
Proceedings of the National Academy of Sciences 102 (29), 10070-10075, 2005
4462005
The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity
N Barretto, D Jukneliene, K Ratia, Z Chen, AD Mesecar, SC Baker
Journal of virology 79 (24), 15189-15198, 2005
4362005
The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds
YM BŠez-Santos, SES John, AD Mesecar
Antiviral research 115, 21-38, 2015
4202015
The allosteric regulation of pyruvate kinase by fructose-1, 6-bisphosphate
MS Jurica, A Mesecar, PJ Heath, W Shi, T Nowak, BL Stoddard
Structure 6 (2), 195-210, 1998
4111998
Structural Basis for Tumor Pyruvate Kinase M2 Allosteric Regulation and Catalysis,
JD Dombrauckas, BD Santarsiero, AD Mesecar
Biochemistry 44 (27), 9417-9429, 2005
3582005
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme
K Ratia, KS Saikatendu, BD Santarsiero, N Barretto, SC Baker, ...
Proceedings of the National Academy of Sciences 103 (15), 5717-5722, 2006
3362006
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms: direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding
X Zhang, L Gan, H Pan, S Guo, X He, ST Olson, A Mesecar, S Adam, ...
Journal of Biological Chemistry 277 (47), 45276-45284, 2002
3282002
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ...
Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008
2832008
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling
M Frieman, K Ratia, RE Johnston, AD Mesecar, RS Baric
Journal of virology 83 (13), 6689-6705, 2009
2712009
Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor
JE Burdette, J Liu, S Chen, DS Fabricant, CE Piersen, EL Barker, ...
Journal of Agricultural and Food Chemistry 51 (19), 5661-5670, 2003
2642003
Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2
AL Eggler, KA Gay, AD Mesecar
Molecular nutrition & food research 52 (S1), S84-S94, 2008
2592008
Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase
BM Dietz, YH Kang, G Liu, AL Eggler, P Yao, LR Chadwick, GF Pauli, ...
Chemical research in toxicology 18 (8), 1296-1305, 2005
2592005
Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences
AD Mesecar, BL Stoddard, DE Koshland
Science 277 (5323), 202-206, 1997
2521997
Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases
MA Clementz, Z Chen, BS Banach, Y Wang, L Sun, K Ratia, ...
Journal of virology 84 (9), 4619-4629, 2010
2502010
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris
BY Hwang, BN Su, H Chai, Q Mi, LBS Kardono, JJ Afriastini, S Riswan, ...
The Journal of organic chemistry 69 (10), 3350-3358, 2004
2212004
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
2172020
Modification of keap1 cysteine residues by sulforaphane
C Hu, AL Eggler, AD Mesecar, RB Van Breemen
Chemical research in toxicology 24 (4), 515-521, 2011
2062011
New Chemical Constituents of Euphorbia quinquecostata and Absolute Configuration Assignment by a Convenient Mosher Ester Procedure Carried Out in NMR†…
BN Su, EJ Park, ZH Mbwambo, BD Santarsiero, AD Mesecar, HHS Fong, ...
Journal of natural products 65 (9), 1278-1282, 2002
2012002
Sites of alkylation of human Keap1 by natural chemoprevention agents
Y Luo, AL Eggler, D Liu, G Liu, AD Mesecar, RB van Breemen
Journal of the American Society for Mass Spectrometry 18 (12), 2226-2232, 2007
1852007
Pleiotropic mechanisms facilitated by resveratrol and its metabolites
B Calamini, K Ratia, MG Malkowski, M Cuendet, JM Pezzuto, ...
Biochemical Journal 429 (2), 273-282, 2010
1832010
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