Matt Kaeberlein
Matt Kaeberlein
Professor of Pathology, University of Washington
Email verificata su - Home page
Citata da
Citata da
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
SI Imai, CM Armstrong, M Kaeberlein, L Guarente
Nature 403 (6771), 795-800, 2000
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
M Kaeberlein, M McVey, L Guarente
Genes & development 13 (19), 2570-2580, 1999
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
M Kaeberlein, RW Powers, KK Steffen, EA Westman, D Hu, N Dang, ...
Science 310 (5751), 1193-1196, 2005
mTOR is a key modulator of ageing and age-related disease
SC Johnson, PS Rabinovitch, M Kaeberlein
Nature 493 (7432), 338-345, 2013
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
SJ Lin, M Kaeberlein, AA Andalis, LA Sturtz, PA Defossez, VC Culotta, ...
Nature 418 (6895), 344-348, 2002
Extension of chronological life span in yeast by decreased TOR pathway signaling
RW Powers, M Kaeberlein, SD Caldwell, BK Kennedy, S Fields
Genes & development 20 (2), 174-184, 2006
Substrate-specific activation of sirtuins by resveratrol
M Kaeberlein, T McDonagh, B Heltweg, J Hixon, EA Westman, ...
Journal of Biological Chemistry 280 (17), 17038-17045, 2005
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
C Burnett, S Valentini, F Cabreiro, M Goss, M Somogyvri, MD Piper, ...
nature 477 (7365), 482-485, 2011
Histone H4 lysine 16 acetylation regulates cellular lifespan
W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ...
Nature 459 (7248), 802-807, 2009
Replicative and Chronological Aging in Saccharomyces cerevisiae
VD Longo, GS Shadel, M Kaeberlein, B Kennedy
Cell metabolism 16 (1), 18-31, 2012
Sir2-independent life span extension by calorie restriction in yeast
M Kaeberlein, KT Kirkland, S Fields, BK Kennedy
PLoS Biol 2 (9), e296, 2004
Lessons on longevity from budding yeast
M Kaeberlein
Nature 464 (7288), 513-519, 2010
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4
KK Steffen, VL MacKay, EO Kerr, M Tsuchiya, D Hu, LA Fox, N Dang, ...
Cell 133 (2), 292-302, 2008
Elimination of replication block protein Fob1 extends the life span of yeast mother cells
PA Defossez, R Prusty, M Kaeberlein, SJ Lin, P Ferrigno, PA Silver, ...
Molecular cell 3 (4), 447-455, 1999
The TOR pathway comes of age
MN Stanfel, LS Shamieh, M Kaeberlein, BK Kennedy
Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1067-1074, 2009
A molecular mechanism of chronological aging in yeast
CR Burtner, CJ Murakami, BK Kennedy, M Kaeberlein
Cell cycle 8 (8), 1256-1270, 2009
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome
SC Johnson, ME Yanos, EB Kayser, A Quintana, M Sangesland, ...
Science 342 (6165), 1524-1528, 2013
Lifespan extension in Caenorhabditis elegans by complete removal of food
TL Kaeberlein, ED Smith, M Tsuchiya, KL Welton, JH Thomas, S Fields, ...
Aging cell 5 (6), 487-494, 2006
Replicative aging in yeast: the means to the end
KA Steinkraus, M Kaeberlein, BK Kennedy
Annual review of cell and developmental biology 24, 29-54, 2008
Rapamycin reverses elevated mTORC1 signaling in lamin A/C–deficient mice, rescues cardiac and skeletal muscle function, and extends survival
FJ Ramos, SC Chen, MG Garelick, DF Dai, CY Liao, KH Schreiber, ...
Science translational medicine 4 (144), 144ra103-144ra103, 2012
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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