Antonella Scorziello
Antonella Scorziello
Associate Professor of Pharmacology
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Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
AY Abramov, A Scorziello, MR Duchen
Journal of Neuroscience 27 (5), 1129-1138, 2007
Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis
C Galli, O Meucci, A Scorziello, TM Werge, P Calissano, G Schettini
Journal of Neuroscience 15 (2), 1172-1179, 1995
Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism
A Livigni, A Scorziello, S Agnese, A Adornetto, A Carlucci, C Garbi, ...
Molecular biology of the cell 17 (1), 263-271, 2006
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage
P Molinaro, O Cuomo, G Pignataro, F Boscia, R Sirabella, A Pannaccione, ...
Journal of Neuroscience 28 (5), 1179-1184, 2008
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats
G Pignataro, A Tortiglione, A Scorziello, L Giaccio, A Secondo, B Severino, ...
Neuropharmacology 46 (3), 439-448, 2004
Post‐ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy
G Pignataro, A Scorziello, G Di Renzo, L Annunziato
The FEBS journal 276 (1), 46-57, 2009
Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia
A Carlucci, A Adornetto, A Scorziello, D Viggiano, M Foca, O Cuomo, ...
The EMBO journal 27 (7), 1073-1084, 2008
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial …
A Secondo, RI Staiano, A Scorziello, R Sirabella, F Boscia, A Adornetto, ...
Cell calcium 42 (6), 521-535, 2007
Somatostatin Inhibits PC Cl3 Thyroid Cell Proliferation through the Modulation of Phosphotyrosine Phosphatase Activity IMPAIRMENT OF THE SOMATOSTATINERGIC EFFECTS BY STABLE …
T Florio, A Scorziello, M Fattore, V D'Alto, S Salzano, G Rossi, ...
Journal of Biological Chemistry 271 (11), 6129-6136, 1996
Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126-induced astroglial proliferation
T Florio, M Grimaldi, A Scorziello, M Salmona, O Bugiani, F Tagliavini, ...
Biochemical and biophysical research communications 228 (2), 397-405, 1996
NCX1 expression and functional activity increase in microglia invading the infarct core
F Boscia, R Gala, A Pannaccione, A Secondo, A Scorziello, G Di Renzo, ...
Stroke 40 (11), 3608-3617, 2009
Up-regulation and increased activity of KV3. 4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death
A Pannaccione, F Boscia, A Scorziello, A Adornetto, P Castaldo, ...
Molecular pharmacology 72 (3), 665-673, 2007
HIF‐1α reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion
C Matrone, G Pignataro, P Molinaro, C Irace, A Scorziello, GF Di Renzo, ...
Journal of neurochemistry 90 (2), 368-378, 2004
Na+–Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory
P Molinaro, D Viggiano, R Nisticò, R Sirabella, A Secondo, F Boscia, ...
Journal of Neuroscience 31 (20), 7312-7321, 2011
Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen glucose deprivation followed by reoxygenation
A Scorziello, C Pellegrini, L Forte, A Tortiglione, A Gioielli, S Iossa, ...
Journal of neuroscience research 63 (1), 20-26, 2001
Anoxia-Induced NF-kB-Dependent Upregulation of NCX1 Contributes to Ca2+ Refilling Into Endoplasmic Reticulum in Cortical Neurons
R Sirabella, A Secondo, A Pannaccione, A Scorziello, V Valsecchi, ...
Stroke 40 (3), 922-929, 2009
Control of PKA stability and signalling by the RING ligase praja2
L Lignitto, A Carlucci, M Sepe, E Stefan, O Cuomo, R Nisticò, A Scorziello, ...
Nature cell biology 13 (4), 412-422, 2011
Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca2+ homeostasis
F Maddalena, G Laudiero, A Piscazzi, A Secondo, A Scorziello, ...
Cancer research 71 (24), 7659-7669, 2011
NO‐induced neuroprotection in ischemic preconditioning stimulates mitochondrial Mn‐SOD activity and expression via RAS/ERK1/2 pathway
A Scorziello, M Santillo, A Adornetto, C Dell’Aversano, R Sirabella, ...
Journal of neurochemistry 103 (4), 1472-1480, 2007
NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning
V Valsecchi, G Pignataro, A Del Prete, R Sirabella, C Matrone, F Boscia, ...
Stroke 42 (3), 754-763, 2011
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