| Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimer’s disease not evident in mouse models BA Friedman, K Srinivasan, G Ayalon, WJ Meilandt, H Lin, MA Huntley, ... Cell reports 22 (3), 832-847, 2018 | 530 | 2018 |
| Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ... Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012 | 406 | 2012 |
| Changes in the synaptic proteome in tauopathy and rescue of tau-induced synapse loss by C1q antibodies B Dejanovic, MA Huntley, A De Mazière, WJ Meilandt, T Wu, K Srinivasan, ... Neuron 100 (6), 1322-1336. e7, 2018 | 372 | 2018 |
| Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses K Srinivasan, BA Friedman, JL Larson, BE Lauffer, LD Goldstein, ... Nature communications 7 (1), 11295, 2016 | 318 | 2016 |
| Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention K Yap, ZQ Lim, P Khandelia, B Friedman, EV Makeyev Genes & development 26 (11), 1209-1223, 2012 | 288 | 2012 |
| Alzheimer’s patient microglia exhibit enhanced aging and unique transcriptional activation K Srinivasan, BA Friedman, A Etxeberria, MA Huntley, MP van Der Brug, ... Cell reports 31 (13), 2020 | 263 | 2020 |
| Glucagon couples hepatic amino acid catabolism to mTOR-dependent regulation of α-cell mass MJ Solloway, A Madjidi, C Gu, J Eastham-Anderson, HJ Clarke, N Kljavin, ... Cell reports 12 (3), 495-510, 2015 | 178 | 2015 |
| Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia TL Cuellar, AM Herzner, X Zhang, Y Goyal, C Watanabe, BA Friedman, ... Journal of Cell Biology 216 (11), 3535-3549, 2017 | 172 | 2017 |
| Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology SH Lee, WJ Meilandt, L Xie, VD Gandham, H Ngu, KH Barck, ... Neuron 109 (8), 1283-1301. e6, 2021 | 162 | 2021 |
| Patterns of intron gain and loss in fungi CB Nielsen, B Friedman, B Birren, CB Burge, JE Galagan PLoS biology 2 (12), e422, 2004 | 152 | 2004 |
| Intricate interplay between astrocytes and motor neurons in ALS HP Phatnani, P Guarnieri, BA Friedman, MA Carrasco, M Muratet, ... Proceedings of the National Academy of Sciences 110 (8), E756-E765, 2013 | 149 | 2013 |
| Microglia in brain development, homeostasis, and neurodegeneration CJ Bohlen, BA Friedman, B Dejanovic, M Sheng Annual Review of Genetics 53, 263-288, 2019 | 147 | 2019 |
| IκB kinase ε (IKKε) regulates the balance between type I and type II interferon responses SL Ng, BA Friedman, S Schmid, J Gertz, RM Myers, BR Tenoever, ... Proceedings of the National Academy of Sciences 108 (52), 21170-21175, 2011 | 142 | 2011 |
| Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer … WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ... Journal of Neuroscience 40 (9), 1956-1974, 2020 | 132 | 2020 |
| Functional significance of isoform diversification in the protocadherin gamma gene cluster WV Chen, FJ Alvarez, JL Lefebvre, B Friedman, C Nwakeze, E Geiman, ... Neuron 75 (3), 402-409, 2012 | 125 | 2012 |
| Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation MC Chang, K Srinivasan, BA Friedman, E Suto, Z Modrusan, WP Lee, ... Journal of Experimental Medicine 214 (9), 2611-2628, 2017 | 124 | 2017 |
| Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination K Shen, M Reichelt, RV Kyauk, H Ngu, YAA Shen, O Foreman, ... Cell Reports 34 (10), 2021 | 79 | 2021 |
| Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models B Dejanovic, T Wu, MC Tsai, D Graykowski, VD Gandham, CM Rose, ... Nature aging 2 (9), 837-850, 2022 | 78 | 2022 |
| Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types YJJ Chen, BA Friedman, C Ha, S Durinck, J Liu, JL Rubenstein, ... Scientific reports 7 (1), 45656, 2017 | 69 | 2017 |
| Disease-associated oligodendrocyte responses across neurodegenerative diseases S Pandey, K Shen, SH Lee, YAA Shen, Y Wang, M Otero-García, ... Cell reports 40 (8), 2022 | 68 | 2022 |
David HansenAssociate Professor, Brigham Young UniversityEmail verificata su chem.byu.edu
