TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity A Caputo, E Caci, L Ferrera, N Pedemonte, C Barsanti, E Sondo, U Pfeffer, ... Science 322 (5901), 590-594, 2008 | 1408 | 2008 |
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ... The Journal of clinical investigation 115 (9), 2564-2571, 2005 | 671 | 2005 |
Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ... The Journal of clinical investigation 115 (9), 2564-2571, 2005 | 671 | 2005 |
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia P Scudieri, E Caci, S Bruno, L Ferrera, M Schiavon, E Sondo, V Tomati, ... The Journal of physiology 590 (23), 6141-6155, 2012 | 179 | 2012 |
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro LJV Galietta, P Pagesy, C Folli, E Caci, L Romio, B Costes, E Nicolis, ... The Journal of Immunology 168 (2), 839-845, 2002 | 173 | 2002 |
Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels N Pedemonte, E Caci, E Sondo, A Caputo, K Rhoden, U Pfeffer, ... The Journal of Immunology 178 (8), 5144-5153, 2007 | 169 | 2007 |
Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway L Petecchia, F Sabatini, C Usai, E Caci, L Varesio, GA Rossi Laboratory investigation 92 (8), 1140-1148, 2012 | 156 | 2012 |
Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347 mutagenesis E Caci, A Caputo, A Hinzpeter, N Arous, P Fanen, N Sonawane, ... Biochemical Journal 413 (1), 135-142, 2008 | 129 | 2008 |
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms P Scudieri, E Caci, A Venturini, E Sondo, G Pianigiani, C Marchetti, ... The Journal of physiology 593 (17), 3829-3848, 2015 | 97 | 2015 |
Goblet cell hyperplasia requires high bicarbonate transport to support mucin release G Gorrieri, P Scudieri, E Caci, M Schiavon, V Tomati, F Sirci, F Napolitano, ... Scientific reports 6 (1), 36016, 2016 | 94 | 2016 |
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling E Sondo, V Tomati, E Caci, AI Esposito, U Pfeffer, N Pedemonte, ... American Journal of Physiology-Cell Physiology 301 (4), C872-C885, 2011 | 94 | 2011 |
The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis E Sondo, E Caci, LJV Galietta The international journal of biochemistry & cell biology 52, 73-76, 2014 | 83 | 2014 |
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds E Caci, C Folli, O Zegarra-Moran, T Ma, MF Springsteel, RE Sammelson, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (1 …, 2003 | 75 | 2003 |
Antihypertensive 1, 4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations N Pedemonte, T Diena, E Caci, E Nieddu, M Mazzei, R Ravazzolo, ... Molecular pharmacology 68 (6), 1736-1746, 2005 | 71 | 2005 |
Gelsolin secretion in interleukin-4–treated bronchial epithelia and in asthmatic airways G Candiano, M Bruschi, N Pedemonte, E Caci, S Liberatori, L Bini, ... American journal of respiratory and critical care medicine 172 (9), 1090-1096, 2005 | 68 | 2005 |
Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis … N Pedemonte, V Tomati, E Sondo, E Caci, E Millo, A Armirotti, G Damonte, ... Journal of Biological Chemistry 286 (17), 15215-15226, 2011 | 67 | 2011 |
Pharmacological inhibition of the ubiquitin ligase RNF5 rescues F508del-CFTR in cystic fibrosis airway epithelia E Sondo, F Falchi, E Caci, L Ferrera, E Giacomini, E Pesce, V Tomati, ... Cell Chemical Biology 25 (7), 891-905. e8, 2018 | 65 | 2018 |
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree C Marconi, P Brunamonti Binello, G Badiali, E Caci, R Cusano, ... European Journal of Human Genetics 21 (6), 613-619, 2013 | 65 | 2013 |
Correction of G551D‐CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB‐07 O Zegarra‐Moran, L Romio, C Folli, E Caci, F Becq, JM Vierfond, Y Mettey, ... British journal of pharmacology 137 (4), 504-512, 2002 | 65 | 2002 |
Genetic inhibition of the ubiquitin ligase Rnf5 attenuates phenotypes associated to F508del cystic fibrosis mutation V Tomati, E Sondo, A Armirotti, E Caci, E Pesce, M Marini, A Gianotti, ... Scientific reports 5 (1), 12138, 2015 | 58 | 2015 |