Lance Munn
Lance Munn
Harvard Medical School
Verified email at - Homepage
TitleCited byYear
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ...
Nature medicine 10 (2), 145, 2004
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases
F Winkler, SV Kozin, RT Tong, SS Chae, MF Booth, I Garkavtsev, L Xu, ...
Cancer cell 6 (6), 553-563, 2004
Lymphatic metastasis in the absence of functional intratumor lymphatics
TP Padera, A Kadambi, E di Tomaso, CM Carreira, EB Brown, Y Boucher, ...
Science 296 (5574), 1883-1886, 2002
Normalization of the vasculature for treatment of cancer and other diseases
S Goel, DG Duda, L Xu, LL Munn, Y Boucher, D Fukumura, RK Jain
Physiological reviews 91 (3), 1071-1121, 2011
Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood
YS Chang, E di Tomaso, DM McDonald, R Jones, RK Jain, LL Munn
Proceedings of the National Academy of Sciences 97 (26), 14608-14613, 2000
Dissecting tumour pathophysiology using intravital microscopy
RK Jain, LL Munn, D Fukumura
Nature Reviews Cancer 2 (4), 266, 2002
Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging
BJ Vakoc, RM Lanning, JA Tyrrell, TP Padera, LA Bartlett, ...
Nature medicine 15 (10), 1219, 2009
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model
RK Jain, RT Tong, LL Munn
Cancer research 67 (6), 2729-2735, 2007
During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium.
RJ Melder, GC Koenig, BP Witwer, N Safabakhsh, LL Munn, RK Jain
Nature medicine 2 (9), 992-997, 1996
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: Continued experience of a phase I trial in rectal …
CG Willett, Y Boucher, DG Duda, E Di Tomaso, LL Munn, RT Tong, ...
Journal of Clinical Oncology 23 (31), 8136-8139, 2005
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
Y Huang, J Yuan, E Righi, WS Kamoun, M Ancukiewicz, J Nezivar, ...
Proceedings of the National Academy of Sciences 109 (43), 17561-17566, 2012
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
T Stylianopoulos, JD Martin, VP Chauhan, SR Jain, B Diop-Frimpong, ...
Proceedings of the National Academy of Sciences 109 (38), 15101-15108, 2012
Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre‐clinical models
DAI Fukumura, DG Duda, LL Munn, RK Jain
Microcirculation 17 (3), 206-225, 2010
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors
RB Campbell, D Fukumura, EB Brown, LM Mazzola, Y Izumi, RK Jain, ...
Cancer research 62 (23), 6831-6836, 2002
Fluid forces control endothelial sprouting
JW Song, LL Munn
Proceedings of the National Academy of Sciences 108 (37), 15342-15347, 2011
Mechanical compression drives cancer cells toward invasive phenotype
MT Janet, G Cheng, JA Tyrrell, SA Wilcox-Adelman, Y Boucher, RK Jain, ...
Proceedings of the National Academy of Sciences 109 (3), 911-916, 2012
Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells
G Cheng, J Tse, RK Jain, LL Munn
PLoS one 4 (2), e4632, 2009
Modeling the flow of dense suspensions of deformable particles in three dimensions
MM Dupin, I Halliday, CM Care, L Alboul, LL Munn
Physical Review E 75 (6), 066707, 2007
Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis
S Patan, LL Munn, RK Jain
Microvascular research 51 (2), 260-272, 1996
Edema control by cediranib, a vascular endothelial growth factor receptor–targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice
WS Kamoun, CD Ley, CT Farrar, AM Duyverman, J Lahdenranta, ...
Journal of clinical oncology 27 (15), 2542, 2009
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