|How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein?|
BF Shaw, JS Valentine
Trends in biochemical sciences 32 (2), 78-85, 2007
|Destabilization of apoprotein is insufficient to explain Cu, Zn-superoxide dismutase-linked ALS pathogenesis|
JA Rodriguez, BF Shaw, A Durazo, SH Sohn, PA Doucette, AM Nersissian, ...
Proceedings of the National Academy of Sciences 102 (30), 10516-10521, 2005
|PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model|
CK Oh, B Ariue, RF Alban, B Shaw, SH Cho
Biochemical and biophysical research communications 294 (5), 1155-1160, 2002
|Abnormal SDS‐PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding|
Y Shi, RA Mowery, J Ashley, M Hentz, AJ Ramirez, B Bilgicer, ...
Protein Science 21 (8), 1197-1209, 2012
|Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase|
ZAO Durer, JA Cohlberg, P Dinh, S Padua, K Ehrenclou, S Downes, ...
PloS one 4 (3), e5004, 2009
|Binding of a single zinc ion to one subunit of copper− zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein|
SZ Potter, H Zhu, BF Shaw, JA Rodriguez, PA Doucette, SH Sohn, ...
Journal of the American Chemical Society 129 (15), 4575-4583, 2007
|Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1|
BF Shaw, HL Lelie, A Durazo, AM Nersissian, G Xu, PK Chan, EB Gralla, ...
Journal of Biological Chemistry 283 (13), 8340-8350, 2008
|Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry|
BF Shaw, A Durazo, AM Nersissian, JP Whitelegge, KF Faull, ...
Journal of Biological Chemistry 281 (26), 18167-18176, 2006
|Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation|
BF Shaw, GF Schneider, B Bilgišer, GK Kaufman, JM Neveu, WS Lane, ...
Protein Science 17 (8), 1446-1455, 2008
|Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase|
K Sea, SH Sohn, A Durazo, Y Sheng, BF Shaw, X Cao, AB Taylor, ...
Journal of Biological Chemistry 290 (4), 2405-2418, 2015
|Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations|
Y Shi, NR Rhodes, A Abdolvahabi, T Kohn, NP Cook, AA Marti, BF Shaw
Journal of the American Chemical Society 135 (42), 15897-15908, 2013
|Pathway for unfolding of ubiquitin in sodium dodecyl sulfate, studied by capillary electrophoresis|
GF Schneider, BF Shaw, A Lee, E Carillho, GM Whitesides
Journal of the American Chemical Society 130 (51), 17384-17393, 2008
|Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants|
BF Shaw, GF Schneider, H Arthanari, M Narovlyansky, D Moustakas, ...
Journal of the American Chemical Society 133 (44), 17681-17695, 2011
|Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded β-barrel at physiological temperature|
A Durazo, BF Shaw, M Chattopadhyay, KF Faull, AM Nersissian, ...
Journal of Biological Chemistry 284 (49), 34382-34389, 2009
|Arresting amyloid with coulomb’s law: acetylation of ALS-linked SOD1 by aspirin impedes aggregation|
A Abdolvahabi, Y Shi, NR Rhodes, NP Cook, AA MartÝ, BF Shaw
Biophysical journal 108 (5), 1199-1212, 2015
|A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids|
B Bilgišer, SW Thomas III, BF Shaw, GK Kaufman, VM Krishnamurthy, ...
Journal of the American Chemical Society 131 (26), 9361-9367, 2009
|Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site|
NJ Alves, MM Champion, JF Stefanick, MW Handlogten, DT Moustakas, ...
Biomaterials 34 (22), 5700-5710, 2013
|Stochastic formation of fibrillar and amorphous superoxide dismutase oligomers linked to amyotrophic lateral sclerosis|
A Abdolvahabi, Y Shi, A Chuprin, S Rasouli, BF Shaw
ACS chemical neuroscience 7 (6), 799-810, 2016
|Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability|
BF Shaw, H Arthanari, M Narovlyansky, A Durazo, DP Frueh, MP Pollastri, ...
Journal of the American Chemical Society 132 (49), 17411-17425, 2010
|Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma|
A Abdolvahabi, BW Taylor, RL Holden, EV Shaw, A Kentsis, ...
PloS one 8 (10), e76677, 2013