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Siddharth Shukla
Siddharth Shukla
Email verificata su colorado.edu
Titolo
Citata da
Citata da
Anno
Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook
S Shukla, CS Sumaria, PI Pradeepkumar
ChemMedChem 5 (3), 328-349, 2010
2362010
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects
S Shukla, JC Schmidt, KC Goldfarb, TR Cech, R Parker
Nature structural & molecular biology 23 (4), 286, 2016
1272016
Hypo-and hyper-assembly diseases of RNA–protein complexes
S Shukla, R Parker
Trends in molecular medicine 22 (7), 615-628, 2016
702016
The RNase PARN controls the levels of specific miRNAs that contribute to p53 regulation
S Shukla, GA Bjerke, D Muhlrad, R Yi, R Parker
Molecular cell 73 (6), 1204-1216. e4, 2019
652019
Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion
S Shukla, R Parker
Proceedings of the National Academy of Sciences 111 (32), E3277-E3286, 2014
572014
PARN modulates Y RNA stability and its 3′-end formation
S Shukla, R Parker
Molecular and Cellular Biology 37 (20), e00264-17, 2017
392017
Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita
WC Fok, S Shukla, AT Vessoni, KA Brenner, R Parker, CM Sturgeon, ...
Blood, The Journal of the American Society of Hematology 133 (12), 1308-1312, 2019
362019
Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita
S Shukla, HC Jeong, CM Sturgeon, R Parker, LFZ Batista
Blood advances 4 (12), 2717-2722, 2020
332020
USB1 is a miRNA deadenylase that regulates hematopoietic development
HC Jeong, S Shukla, WC Fok, TN Huynh, LFZ Batista, R Parker
Science 379 (6635), 901-907, 2023
122023
Identification of PARN nuclease activity inhibitors by computational-based docking and high-throughput screening
TN Huynh, S Shukla, P Reigan, R Parker
Scientific Reports 13 (1), 5244, 2023
2023
PAPD5 Inhibition As A Treatment For Dyskeratosis Congenita, Aplastic Anemia And Myelodysplastic Syndrome Caused By Reduced Telomerase RNA Levels
RR Parker, S Shukla, LFZ Batista, H Jeong
US Patent App. 17/775,133, 2022
2022
Usb1 Directed Regulation Of Mirnas Related Hematopoietic Differentiation And Affected In Multiple Forms Of Leukemia
RR Parker, S Shukla, LFZ Batista, H Jeong
US Patent App. 17/466,448, 2022
2022
USB1 Is a miRNA Deadenylase That Regulates Hematopoietic Development
HC Jeong, S Shukla, R Parker, L Batista
Blood 138, 2191, 2021
2021
Parn as a biomarker and therapeutic target
RR PARKER, S Shukla
2020
Investigation of RNA Quality Control Pathways in RNP Hypo-Assembly Diseases
S Shukla
2016
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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