| Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies W Schaefer, JT Regula, M Bähner, J Schanzer, R Croasdale, H Dürr, ... Proceedings of the National academy of Sciences 108 (27), 11187-11192, 2011 | 521 | 2011 |
| Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ... MAbs 5 (1), 22-33, 2013 | 365 | 2013 |
| Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies G Niederfellner, A Lammens, O Mundigl, GJ Georges, W Schaefer, ... Blood, The Journal of the American Society of Hematology 118 (2), 358-367, 2011 | 297 | 2011 |
| NMR investigation of the multidrug transporter EmrE, an integral membrane protein M Schwaiger, M Lebendiker, H Yerushalmi, M Coles, A Gröger, ... European journal of biochemistry 254 (3), 610-619, 1998 | 118 | 1998 |
| NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNA C Klein, E Planker, T Diercks, H Kessler, KP Kunkele, K Lang, S Hansen, ... Journal of Biological Chemistry 276 (52), 49020-49027, 2001 | 97 | 2001 |
| Cooperative binding of p53 to DNA: regulation by protein–protein interactions through a double salt bridge A Dehner, C Klein, S Hansen, L Müller, J Buchner, M Schwaiger, ... Angewandte Chemie International Edition 44 (33), 5247-5251, 2005 | 66 | 2005 |
| A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl‐Prolyl cis/trans Isomerase (PPIase … R Siegrist, M Zürcher, C Baumgartner, P Seiler, F Diederich, S Daum, ... Helvetica chimica acta 90 (2), 217-259, 2007 | 27 | 2007 |
| Monovalent Antigen Binding Proteins B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ... US Patent App. 13/406,503, 2012 | 26 | 2012 |
| Dual FC antigen binding proteins B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ... US Patent 9,982,036, 2018 | 24 | 2018 |
| Response to: monoclonal antibodies targeting CD20 C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ... MAbs 5 (3), 337-338, 2013 | 17 | 2013 |
| Crystal Structure Analysis Reveals That the Novel Type II Anti-CD20 Antibody GA101 Interacts with a Similar Epitope as Rituximab and Ocrelizumab but in a Fundamentally … GJ Niederfellner, A Lammens, M Schwaiger, G Georges, K Wiechmann, ... Blood, The Journal of the American Society of Hematology 114 (22), 3726-3726, 2009 | 16 | 2009 |
| Amide derivatives of 3-phenyl-dihydropyrimido [4, 5-d] pyrimidinones, their manufacture and use as pharmaceutical agents R Engh, H Hertenberger, K Honold, B Masjost, P Rueger, W Schaefer, ... US Patent 7,655,651, 2010 | 13* | 2010 |
| Backbone H-1, C-13 and N-15 resonance assignments for the 25.8 kDa DNA binding domain of the human p63 protein J Furrer Journal of Biomolecular NMR 26 (4), 377-378, 2003 | 12 | 2003 |
| Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties. mAbs. 2013; 5 (1): 22–33 C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ... Oncologist 5 (5), 376-84, 2000 | 12 | 2000 |
| DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity C Sustmann, S Dickopf, JT Regula, H Kettenberger, M Mølhøj, C Gassner, ... MAbs 11 (8), 1402-1414, 2019 | 10 | 2019 |
| Amide derivatives of 7-amino-3-phenyl-dihydropyrimido [4, 5-d] pyrimidinones, their manufacture and use as pharmaceutical agents R Engh, H Hertenberger, K Honold, B Masjost, P Rueger, W Schaefer, ... US Patent 7,494,993, 2009 | 10 | 2009 |
| HSQC-based methyl group selection via gradients in multidimensional NMR spectroscopy of proteins T Diercks, M Schwaiger, H Kessler Journal of Magnetic Resonance 130 (2), 335-340, 1998 | 7 | 1998 |
| Monovalent antigen binding proteins B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ... US Patent 10,611,825, 2020 | 6 | 2020 |
| In vitro folding and characterization of the p53 DNA binding domain C Klein, F Hesse, A Dehner, RA Engh, M Schwaiger, S Hansen Walter de Gruyter 385 (1), 95-102, 2004 | 6 | 2004 |
| Kooperative Bindung von p53 an DNA: Regulation durch Protein‐Protein‐Wechselwirkung unter Bildung einer doppelten Salzbrücke A Dehner, C Klein, S Hansen, L Müller, J Buchner, M Schwaiger, ... Angewandte Chemie 117 (33), 5381-5386, 2005 | 5 | 2005 |
Christian KleinRoche Pharma Research and Early Development, Roche Innovation Center ZurichVerified email at roche.com
