| Design of functional metalloproteins Y Lu, N Yeung, N Sieracki, NM Marshall Nature 460 (7257), 855-862, 2009 | 748 | 2009 |
| Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 434 | 2019 |
| Rationally tuning the reduction potential of a single cupredoxin beyond the natural range NM Marshall, DK Garner, TD Wilson, YG Gao, H Robinson, MJ Nilges, ... Nature 462 (7269), 113-116, 2009 | 326 | 2009 |
| Reversal of indoleamine 2, 3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme TA Triplett, KC Garrison, N Marshall, M Donkor, J Blazeck, C Lamb, ... Nature biotechnology 36 (8), 758-764, 2018 | 231 | 2018 |
| Deep dive into machine learning models for protein engineering Y Xu, D Verma, RP Sheridan, A Liaw, J Ma, NM Marshall, J McIntosh, ... Journal of chemical information and modeling 60 (6), 2773-2790, 2020 | 169 | 2020 |
| IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions CH Lee, G Romain, W Yan, M Watanabe, W Charab, B Todorova, J Lee, ... Nature immunology 18 (8), 889-898, 2017 | 135 | 2017 |
| Direct, electrocatalytic oxygen reduction by laccase on anthracene-2-methanethiol-modified gold MS Thorum, CA Anderson, JJ Hatch, AS Campbell, NM Marshall, ... The journal of physical chemistry letters 1 (15), 2251-2254, 2010 | 114 | 2010 |
| Design of a single protein that spans the entire 2-V range of physiological redox potentials P Hosseinzadeh, NM Marshall, KN Chacón, Y Yu, MJ Nilges, SY New, ... Proceedings of the National Academy of Sciences 113 (2), 262-267, 2016 | 106 | 2016 |
| Systematic Tuning of Heme Redox Potentials and Its Effects on O2 Reduction Rates in a Designed Oxidase in Myoglobin A Bhagi-Damodaran, ID Petrik, NM Marshall, H Robinson, Y Lu Journal of the American Chemical Society 136 (34), 11882-11885, 2014 | 88 | 2014 |
| Spectroscopic and DFT studies of second-sphere variants of the type 1 copper site in azurin: Covalent and nonlocal electrostatic contributions to reduction potentials RG Hadt, N Sun, NM Marshall, KO Hodgson, B Hedman, Y Lu, ... Journal of the American Chemical Society 134 (40), 16701-16716, 2012 | 83 | 2012 |
| Transforming a blue copper into a red copper protein: engineering cysteine and homocysteine into the axial position of azurin using site-directed mutagenesis and expressed … KM Clark, Y Yu, NM Marshall, NA Sieracki, MJ Nilges, NJ Blackburn, ... Journal of the American Chemical Society 132 (29), 10093-10101, 2010 | 81 | 2010 |
| Metalloproteins J Finkelstein Nature 460 (7257), 813-813, 2009 | 80 | 2009 |
| A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability DL Daee, TM Mertz, PV Shcherbakova Proceedings of the National Academy of Sciences 107 (1), 157-162, 2010 | 79 | 2010 |
| A kinase-cGAS cascade to synthesize a therapeutic STING activator JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 60 | 2022 |
| Overcoming “speed limits” in high throughput chromatographic analysis K Zawatzky, CL Barhate, EL Regalado, BF Mann, N Marshall, JC Moore, ... Journal of Chromatography A 1499, 211-216, 2017 | 51 | 2017 |
| Designed azurins show lower reorganization free energies for intraprotein electron transfer O Farver, NM Marshall, S Wherland, Y Lu, I Pecht Proceedings of the National Academy of Sciences 110 (26), 10536-10540, 2013 | 44 | 2013 |
| Reversible S-nitrosylation in an engineered azurin S Tian, J Liu, RE Cowley, P Hosseinzadeh, NM Marshall, Y Yu, ... Nature chemistry 8 (7), 670-677, 2016 | 38 | 2016 |
| Diverse catalytic reactions for the stereoselective synthesis of cyclic dinucleotide MK-1454 T Benkovics, F Peng, EM Phillips, C An, RS Bade, CK Chung, ZEX Dance, ... Journal of the American Chemical Society 144 (13), 5855-5863, 2022 | 33 | 2022 |
| A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site P Hosseinzadeh, S Tian, NM Marshall, J Hemp, T Mullen, MJ Nilges, ... Journal of the American Chemical Society 138 (20), 6324-6327, 2016 | 29 | 2016 |
| Long-range electron transfer in engineered azurins exhibits Marcus inverted region behavior O Farver, P Hosseinzadeh, NM Marshall, S Wherland, Y Lu, I Pecht The Journal of Physical Chemistry Letters 6 (1), 100-105, 2015 | 28 | 2015 |
