| The p66shc adaptor protein controls oxidative stress response and life span in mammals E Migliaccio, M Giorgio, S Mele, G Pelicci, P Reboldi, PP Pandolfi, ... Nature 402 (6759), 309-313, 1999 | 2085 | 1999 |
| A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction G Pelicci, L Lanfrancone, F Grignani, J McGlade, F Cavallo, G Forni, ... Cell 70 (1), 93-104, 1992 | 1701 | 1992 |
| Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 653 | 2017 |
| Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. F Re, A Zanetti, M Sironi, N Polentarutti, L Lanfrancone, E Dejana, ... The Journal of cell biology 127 (2), 537-546, 1994 | 639 | 1994 |
| A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis M Trinei, M Giorgio, A Cicalese, S Barozzi, A Ventura, E Migliaccio, ... Oncogene 21 (24), 3872-3878, 2002 | 534 | 2002 |
| Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor–MAP kinase–fos signalling pathway E Migliaccio, S Mele, AE Salcini, G Pelicci, KMV Lai, G Superti‐Furga, ... The EMBO journal, 1997 | 528 | 1997 |
| High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein F Grignani, T Kinsella, A Mencarelli, M Valtieri, D Riganelli, F Grignani, ... Cancer research 58 (1), 14-19, 1998 | 459 | 1998 |
| Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. N Jonjić, G Peri, S Bernasconi, FL Sciacca, F Colotta, P Pelicci, ... The Journal of experimental medicine 176 (4), 1165-1174, 1992 | 359 | 1992 |
| The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential F Orsini, E Migliaccio, M Moroni, C Contursi, VA Raker, D Piccini, ... Journal of Biological Chemistry 279 (24), 25689-25695, 2004 | 346 | 2004 |
| Not all Shc's roads lead to Ras L Bonfini, E Migliaccio, G Pelicci, L Lanfrancone, PG Pelicci Trends in biochemical sciences 21 (7), 257-261, 1996 | 340 | 1996 |
| The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. G Pelicci, S Giordano, Z Zhen, AE Salcini, L Lanfrancone, A Bardelli, ... Oncogene 10 (8), 1631-1638, 1995 | 277 | 1995 |
| Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc SM Dilworth, CEP Brewster, MD Jones, L Lanfrancone, G Pelicci, ... Nature 367 (6458), 87-90, 1994 | 249 | 1994 |
| Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis M Elgendy, M Ciro, A Hosseini, J Weiszmann, L Mazzarella, E Ferrari, ... Cancer cell 35 (5), 798-815. e5, 2019 | 246 | 2019 |
| Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6 … L Lanfrancone, D Boraschi, P Ghiara, B Falini, F Grignani, G Peri, ... | 214 | 1992 |
| Amplification of the c-myb Oncogene in a Case of Human Acute Myelogenous Leukemia PG Pelicci, L Lanfrancone, MD Brathwaite, SR Wolman, R Dalla-Favera Science 224 (4653), 1117-1121, 1984 | 206 | 1984 |
| A new variant anaplastic lymphoma kinase (ALK)-fusion protein (ATIC-ALK) in a case of ALK-positive anaplastic large cell lymphoma M Trinei, L Lanfrancone, E Campo, K Pulford, DY Mason, PG Pelicci, ... Cancer Research 60 (4), 793-798, 2000 | 198 | 2000 |
| Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth C Di Malta, D Siciliano, A Calcagni, J Monfregola, S Punzi, N Pastore, ... Science 356 (6343), 1188-1192, 2017 | 197 | 2017 |
| Tbx3 represses E-cadherin expression and enhances melanoma invasiveness M Rodriguez, E Aladowicz, L Lanfrancone, CR Goding Cancer research 68 (19), 7872-7881, 2008 | 191 | 2008 |
| Constitutive phosphorylation of Shc proteins in human tumors. G Pelicci, L Lanfrancone, AE Salcini, A Romano, S Mele, G Borrello, ... Oncogene 11 (5), 899-907, 1995 | 181 | 1995 |
| p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells S Pacini, M Pellegrini, E Migliaccio, L Patrussi, C Ulivieri, A Ventura, ... Molecular and Cellular Biology 24 (4), 1747-1757, 2004 | 164 | 2004 |
