A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ... Nature biotechnology 41 (1), 128-139, 2023 | 91 | 2023 |
Transcription imparts architecture, function and logic to enhancer units ND Tippens, J Liang, AKY Leung, SD Wierbowski, A Ozer, JG Booth, ... Nature genetics 52 (10), 1067-1075, 2020 | 64 | 2020 |
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ... Cell systems 10 (4), 333-350. e14, 2020 | 58 | 2020 |
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations R Fragoza, J Das, SD Wierbowski, J Liang, TN Tran, S Liang, JF Beltran, ... Nature communications 10 (1), 4141, 2019 | 58 | 2019 |
Genetics of extreme human longevity to guide drug discovery for healthy ageing ZD Zhang, S Milman, JR Lin, S Wierbowski, H Yu, N Barzilai, ... Nature metabolism 2 (8), 663-672, 2020 | 47 | 2020 |
Cross‐docking benchmark for automated pose and ranking prediction of ligand binding SD Wierbowski, BM Wingert, J Zheng, CJ Camacho Protein Science 29 (1), 298-305, 2020 | 41 | 2020 |
Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studies K Yugandhar, TY Wang, SD Wierbowski, EE Shayhidin, H Yu Nature methods 17 (10), 985-988, 2020 | 31 | 2020 |
A 3D structural SARS-CoV-2–human interactome to explore genetic and drug perturbations SD Wierbowski, S Liang, Y Liu, Y Chen, S Gupta, NM Andre, SM Lipkin, ... Nature methods 18 (12), 1477-1488, 2021 | 23 | 2021 |
Deep learning methods for 3D structural proteome and interactome modeling D Lee, D Xiong, S Wierbowski, L Li, S Liang, H Yu Current opinion in structural biology 73, 102329, 2022 | 19 | 2022 |
A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice SD Wierbowski, TV Vo, P Falter-Braun, TO Jobe, LH Kruse, X Wei, J Liang, ... Proceedings of the National Academy of Sciences 117 (21), 11836-11842, 2020 | 16 | 2020 |
Extracting complementary insights from molecular phenotypes for prioritization of disease-associated mutations SD Wierbowski, R Fragoza, S Liang, H Yu Current opinion in systems biology 11, 107-116, 2018 | 5 | 2018 |
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19 Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao, Y Luo, J Judd, ... Research Square, 2022 | 4 | 2022 |
A full-proteome, interaction-specific characterization of mutational hotspots across human cancers S Chen, Y Liu, Y Zhang, SD Wierbowski, SM Lipkin, X Wei, H Yu Genome Research 32 (1), 135-149, 2022 | 3 | 2022 |
A 3D structural interactome to explore the impact of evolutionary divergence, population variation, and small-molecule drugs on SARS-CoV-2-human protein-protein interactions SD Wierbowski, S Liang, Y Chen, NM Andre, SM Lipkin, GR Whittaker, ... bioRxiv, 2020.10. 13.308676, 2020 | 3 | 2020 |
Macromolecular Connectivity Landscape of Mammalian Brain R Pourhaghighi, PEA Ash, S Phanse, F Goebels, E Malolepsza, K Tsafou, ... | 1 | 2018 |
A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology Y Zhang, AK Leung, T Qiu, L Li, J Zhang, S Wierbowski, J Booth, H Yu bioRxiv, 2023.03. 06.531441, 2023 | | 2023 |
DeepERA: deep learning enables comprehensive identification of drug-target interactions via embedding of heterogeneous data L Li, SD Wierbowski, H Yu bioRxiv, 2023.01. 27.525827, 2023 | | 2023 |
Protein Interaction Network Based Approaches to Characterize Protein Function, Molecularly Profile Genetic Variants, and Investigate Mechanisms Linked to Viral-host Pathology … SD Wierbowski Cornell University, 2022 | | 2022 |
Combining views for newly sequenced organisms Y Zhang, SD Wierbowski, H Yu Nature Machine Intelligence 3 (12), 1011-1012, 2021 | | 2021 |
Considerations in Molecular Docking: Presenting DISCO, a DIrectory of Structures for CrossdOcking, as a Novel Docking Benchmark and Applying it to Refine the Molecular Docking … SD Wierbowski University of Scranton, 2016 | | 2016 |