Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells L Nissim, SD Perli, A Fridkin, P Perez-Pinera, TK Lu Molecular cell 54 (4), 698-710, 2014 | 512 | 2014 |
A tunable dual‐promoter integrator for targeting of cancer cells L Nissim, RH Bar‐Ziv Molecular systems biology 6 (1), 444, 2010 | 163 | 2010 |
Synthetic RNA-based immunomodulatory gene circuits for cancer immunotherapy L Nissim, MR Wu, E Pery, A Binder-Nissim, HI Suzuki, D Stupp, ... Cell 171 (5), 1138-1150. e15, 2017 | 159 | 2017 |
Methods and compositions for the production of guide rna TKT Lu, L Nissim, SD Perli US Patent App. 15/301,135, 2017 | 106 | 2017 |
A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS) MR Wu, L Nissim, D Stupp, E Pery, A Binder-Nissim, K Weisinger, ... Nature communications 10 (1), 2880, 2019 | 69 | 2019 |
The onset of p53-dependent apoptosis plays a role in terminal differentiation of human normoblasts S Peller, J Frenkel, T Lapidot, J Kahn, N Rahimi-Levene, R Yona, ... Oncogene 22 (30), 4648-4655, 2003 | 38 | 2003 |
p53 is a regulator of macrophage differentiation D Matas, M Milyavsky, I Shats, L Nissim, N Goldfinger, V Rotter Cell Death & Differentiation 11 (4), 458-467, 2004 | 32 | 2004 |
Cellular heterogeneity mediates inherent sensitivity–specificity tradeoff in cancer targeting by synthetic circuits M Morel, R Shtrahman, V Rotter, L Nissim, RH Bar-Ziv Proceedings of the National Academy of Sciences 113 (29), 8133-8138, 2016 | 27 | 2016 |
An autonomous system for identifying and governing a cell's state in yeast L Nissim, T Beatus, R Bar-Ziv Physical biology 4 (3), 154, 2007 | 16 | 2007 |
Contact guidance and collective migration in the advancing epithelial monolayer G Lee, L Atia, B Lan, Y Sharma, L Nissim, MR Wu, E Pery, TK Lu, CY Park, ... Connective tissue research 59 (4), 309-315, 2018 | 13 | 2018 |
Synthetic gene circuits B Jusiak, R Daniel, F Farzadfard, L Nissim, O Purcell, J Rubens, TK Lu Synthetic Biology, 2 Volumes, 249, 2015 | 8 | 2015 |
Synthetic circuit-driven expression of heterologous enzymes for disease detection J He, L Nissim, AP Soleimany, A Binder-Nissim, HE Fleming, TK Lu, ... ACS Synthetic Biology 10 (9), 2231-2242, 2021 | 7 | 2021 |
Modeling SARS-CoV-2 Infection in Mice Using Lentiviral hACE2 Vectors Infers Two Modes of Immune Responses to SARS-CoV-2 Infection C Katzman, T Israely, S Melamed, B Politi, A Sittner, Y Yahalom-Ronen, ... Viruses 14 (1), 11, 2021 | 2 | 2021 |
Tumor immunotherapy TKT Lu, L Nissim, MR Wu US Patent App. 15/737,829, 2019 | 2 | 2019 |
Tumor immunotherapy TKT Lu, L Nissim, MR Wu | 1 | 2016 |
Genetic Modification of Tumor-Infiltrating Lymphocytes, Peripheral T Cells, and T-Cell Model Cell Lines H Weinstein-Marom, D Blokon-Kogan, M Levi-Mann, C Katzman, ... Cancer Immunotherapy: Methods and Protocols, 167-186, 2023 | | 2023 |
Synthetic promoters TKT Lu, L Nissim, MR Wu US Patent 11,718,860, 2023 | | 2023 |
Systems and uses thereof for creating synthetic transcriptional logic'and'gates based on pre-mrna trans-splicing L Nissim, G Gross, H Weinstein-Marom, R Keren | | 2020 |
Tumor-Selective Gene Circuits Enable Highly Specific Localized Cancer Immunotherapy MR Wu, L Nissim, E Pery, Y Tabach, PA Sharp, D Stupp, A Binder-Nissim, ... MOLECULAR THERAPY 28 (4), 9-9, 2020 | | 2020 |
Methods and compositions for the production of guide rna TKT Lu, L Nissim, SD PERLI | | 2015 |