| Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis A Kumar, JD Aguirre, TEC Condos, RJ Martinez‐Torres, VK Chaugule, ... The EMBO journal 34 (20), 2506-2521, 2015 | 181 | 2015 |
| A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease DE Spratt, RJ Martinez-Torres, YJ Noh, P Mercier, N Manczyk, KR Barber, ... Nature communications 4, 1983, 2013 | 137 | 2013 |
| Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation JD Aguirre, KM Dunkerley, P Mercier, GS Shaw Proceedings of the National Academy of Sciences 114 (2), 298-303, 2017 | 98 | 2017 |
| Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation J Rabl, RD Bunker, AD Schenk, S Cavadini, ME Gill, W Abdulrahman, ... Molecular Cell, 2019 | 50 | 2019 |
| Synergistic recruitment of UbcH7~ Ub and phosphorylated Ubl domain triggers parkin activation TEC Condos, KM Dunkerley, EA Freeman, KR Barber, JD Aguirre, ... The EMBO journal 37 (23), e100014, 2018 | 38 | 2018 |
| Generation of phospho‐ubiquitin variants by orthogonal translation reveals codon skipping S George, JD Aguirre, DE Spratt, Y Bi, M Jeffery, GS Shaw, P O'Donoghue FEBS letters 590 (10), 1530-1542, 2016 | 35 | 2016 |
| Impact of altered phosphorylation on loss of function of juvenile Parkinsonism–associated genetic variants of the E3 ligase parkin JD Aguirre, KM Dunkerley, R Lam, M Rusal, GS Shaw Journal of Biological Chemistry 293 (17), 6337-6348, 2018 | 30 | 2018 |
| Orphan quality control shapes network dynamics and gene expression KG Mark, SDD Kolla, JD Aguirre, DM Garshott, S Schmitt, DL Haakonsen, ... Cell, 2022 | 12 | 2022 |
| UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ... Molecular Cell, 2023 | 11 | 2023 |
| FANally… A Structure Emerges of the Fanconi Anemia Core Complex JD Aguirre, NH Thomä Trends in Biochemical Sciences, 2020 | 1 | 2020 |
| Autoinhibition and Activation of Parkin JD Aguirre Thesis and Dissertation Repository, 2017 | | 2017 |
