| Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism PT Beernink, BW Segelke, MZ Hadi, JP Erzberger, DM Wilson Iii, B Rupp Journal of molecular biology 307 (4), 1023-1034, 2001 | 226 | 2001 |
| A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination PT Beernink, J Shaughnessy, EM Braga, Q Liu, PA Rice, S Ram, ... The Journal of Immunology 186 (6), 3606-3614, 2011 | 148 | 2011 |
| Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor H-binding protein PT Beernink, JA Welsch, M Bar-Lev, O Koeberling, M Comanducci, ... Infection and immunity 76 (9), 4232-4240, 2008 | 104 | 2008 |
| The modular architecture of meningococcal factor H-binding protein PT Beernink, DM Granoff Microbiology 155 (9), 2873-2883, 2009 | 100 | 2009 |
| Frequency of factor H-binding protein modular groups and susceptibility to cross-reactive bactericidal activity in invasive meningococcal isolates R Pajon, PT Beernink, LH Harrison, DM Granoff Vaccine 28 (9), 2122-2129, 2010 | 90 | 2010 |
| Bactericidal antibody responses induced by meningococcal recombinant chimeric factor H-binding protein vaccines PT Beernink, DM Granoff Infection and immunity 76 (6), 2568-2575, 2008 | 82 | 2008 |
| Meningococcal factor H–binding protein variants expressed by epidemic capsular group A, W-135, and X strains from Africa PT Beernink, DA Caugant, JA Welsch, O Koeberling, DM Granoff The Journal of infectious diseases 199 (9), 1360-1368, 2009 | 81 | 2009 |
| Specificity of protein interactions mediated by BRCT domains of the XRCC1 DNA repair protein PT Beernink, M Hwang, M Ramirez, MB Murphy, SA Doyle, MP Thelen Journal of Biological Chemistry 280 (34), 30206-30213, 2005 | 74 | 2005 |
| Disruption of the aldolase A tetramer into catalytically active monomers. PT Beernink, DR Tolan Proceedings of the National Academy of Sciences 93 (11), 5374-5379, 1996 | 73 | 1996 |
| Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use DM Granoff, P Beernink, JA Welsch US Patent 9,511,131, 2016 | 69 | 2016 |
| Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: implications for the development of a multicomponent group … PT Beernink, JA Welsch, LH Harrison, A Leipus, SL Kaplan, DM Granoff The Journal of infectious diseases 195 (10), 1472-1479, 2007 | 69 | 2007 |
| High-throughput, fluorescence-based screening for soluble protein expression MA Coleman, VH Lao, BW Segelke, PT Beernink Journal of Proteome Research 3 (5), 1024-1032, 2004 | 59 | 2004 |
| Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation JA Endrizzi, PT Beernink, T Alber, HK Schachman Proceedings of the National Academy of Sciences 97 (10), 5077-5082, 2000 | 48 | 2000 |
| Subunit interface mutants of rabbit muscle aldolase form active dimers PT Beernink, DR Tolan Protein Science 3 (9), 1383-1391, 1994 | 48 | 1994 |
| The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein PT Beernink, J Shaughnessy, R Pajon, EM Braga, S Ram, DM Granoff PLoS Pathogens 8 (5), e1002688, 2012 | 46 | 2012 |
| A meningococcal native outer membrane vesicle vaccine with attenuated endotoxin and overexpressed factor H binding protein elicits gonococcal bactericidal antibodies PT Beernink, E Ispasanie, LA Lewis, S Ram, GR Moe, DM Granoff The Journal of infectious diseases 219 (7), 1130-1137, 2019 | 43 | 2019 |
| Assessment of the allosteric mechanism of aspartate transcarbamoylase based on the crystalline structure of the unregulated catalytic subunit PT Beernink, JA Endrizzi, T Alber, HK Schachman Proceedings of the National Academy of Sciences 96 (10), 5388-5393, 1999 | 43 | 1999 |
| Effect of Factor H-Binding Protein Sequence Variation on Factor H Binding and Survival of Neisseria meningitidis in Human Blood KY Dunphy, PT Beernink, B Brogioni, DM Granoff Infection and immunity 79 (1), 353-359, 2011 | 41 | 2011 |
| Rapid genetic grouping of factor H-binding protein (genome-derived neisserial antigen 1870), a promising group B meningococcal vaccine candidate PT Beernink, A Leipus, DM Granoff Clinical and vaccine immunology 13 (7), 758-763, 2006 | 41 | 2006 |
| A region of the N-terminal domain of meningococcal factor H-binding protein that elicits bactericidal antibody across antigenic variant groups PT Beernink, C LoPasso, A Angiolillo, F Felici, D Granoff Molecular immunology 46 (8-9), 1647-1653, 2009 | 40 | 2009 |
