| The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair S Garavaglia, MT Cambria, M Miglio, S Ragusa, V Iacobazzi, F Palmieri, ... Journal of Molecular Biology 342 (5), 1519-1531, 2004 | 200 | 2004 |
| Structure of human NMN adenylyltransferase: a key nuclear enzyme for NAD homeostasis S Garavaglia, I D'Angelo, M Emanuelli, F Carnevali, F Pierella, G Magni, ... Journal of Biological Chemistry 277 (10), 8524-8530, 2002 | 113 | 2002 |
| The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD … S Garavaglia, S Bruzzone, C Cassani, L Canella, G Allegrone, L Sturla, ... Biochemical Journal 441 (1), 131-141, 2012 | 95 | 2012 |
| Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme RG Zhai, M Rizzi, S Garavaglia Cellular and molecular life sciences 66, 2805-2818, 2009 | 92 | 2009 |
| Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid A Moretti, J Li, S Donini, RW Sobol, M Rizzi, S Garavaglia Scientific reports 6 (1), 35710, 2016 | 73 | 2016 |
| A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis S Garavaglia, N Raffaelli, L Finaurini, G Magni, M Rizzi Journal of Biological Chemistry 279 (39), 40980-40986, 2004 | 69 | 2004 |
| Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity A Wilk, F Hayat, R Cunningham, J Li, S Garavaglia, L Zamani, DM Ferraris, ... Scientific reports 10 (1), 651, 2020 | 65 | 2020 |
| Allosteric Regulation of Bacillus subtilis NAD Kinase by Quinolinic Acid S Garavaglia, A Galizzi, M Rizzi Journal of bacteriology 185 (16), 4844-4850, 2003 | 64 | 2003 |
| Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia F Rossi, S Garavaglia, V Montalbano, MA Walsh, M Rizzi Journal of biological chemistry 283 (6), 3559-3566, 2008 | 60 | 2008 |
| Docking simulation and competitive experiments validate the interaction between the 2, 5-xylidine inhibitor and Rigidoporus lignosus laccase MT Cambria, D Di Marino, M Falconi, S Garavaglia, A Cambria Journal of Biomolecular Structure and Dynamics 27 (4), 501-509, 2010 | 57 | 2010 |
| Crystal structure-based selective targeting of the pyridoxal 5′-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement F Rossi, C Valentina, S Garavaglia, KV Sathyasaikumar, R Schwarcz, ... Journal of medicinal chemistry 53 (15), 5684-5689, 2010 | 50 | 2010 |
| Signalling inhibitors against Mycobacterium tuberculosis-early days of a new therapeutic concept in tuberculosis B Hegymegi-Barakonyi, R Szekely, Z Varga, R Kiss, G Borbely, G Nemeth, ... Current medicinal chemistry 15 (26), 2760-2770, 2008 | 47 | 2008 |
| Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells L Quattrini, ELM Gelardi, V Coviello, S Sartini, DM Ferraris, M Mori, ... Journal of Medicinal Chemistry 63 (9), 4603-4616, 2020 | 42 | 2020 |
| Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase F Rossi, S Garavaglia, GB Giovenzana, B Arcà, J Li, M Rizzi Proceedings of the National Academy of Sciences 103 (15), 5711-5716, 2006 | 41 | 2006 |
| The crystal structure of human α‐amino‐β‐carboxymuconate‐ε‐semialdehyde decarboxylase in complex with 1, 3‐dihydroxyacetonephosphate suggests a regulatory link between NAD … S Garavaglia, S Perozzi, L Galeazzi, N Raffaelli, M Rizzi The FEBS journal 276 (22), 6615-6623, 2009 | 40 | 2009 |
| Crystal structure of human nicotinic acid phosphoribosyltransferase AS Marletta, A Massarotti, G Orsomando, G Magni, M Rizzi, S Garavaglia FEBS Open Bio 5, 419-428, 2015 | 37 | 2015 |
| Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants R Miggiano, V Casazza, S Garavaglia, M Ciaramella, G Perugino, M Rizzi, ... Journal of bacteriology 195 (12), 2728-2736, 2013 | 37 | 2013 |
| In silico study of structural determinants modulating the redox potential of Rigidoporus lignosus and other fungal laccases MT Cambria, D Gullotto, S Garavaglia, A Cambria Journal of Biomolecular Structure and Dynamics 30 (1), 89-101, 2012 | 37 | 2012 |
| A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro ELM Gelardi, G Colombo, F Picarazzi, DM Ferraris, A Mangione, ... Cancers 13 (2), 356, 2021 | 29 | 2021 |
| A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus AA Grolla, R Miggiano, D Di Marino, M Bianchi, A Gori, G Orsomando, ... Journal of Biological Chemistry 295 (11), 3635-3651, 2020 | 26 | 2020 |
