|Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity|
JJ Shie, JM Fang, SY Wang, KC Tsai, YSE Cheng, AS Yang, SC Hsiao, ...
Journal of the American Chemical Society 129 (39), 11892-11893, 2007
|Discovery of Highly Potent Tyrosinase Inhibitor, T1, with Significant Anti-Melanogenesis Ability by zebrafish in vivo Assay and Computational Molecular Modeling|
WC Chen, TS Tseng, NW Hsiao, YL Lin, ZH Wen, CC Tsai, YC Lee, ...
Scientific reports 5, 7995, 2015
|Construction of a 3D model of nattokinase, a novel fibrinolytic enzyme from Bacillus natto: a novel nucleophilic catalytic mechanism for nattokinase|
Z Zheng, Z Zuo, Z Liu, K Tsai, A Liu, G Zou
Journal of Molecular Graphics and Modelling 23 (4), 373-380, 2005
|A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity|
JJ Shie, JM Fang, PT Lai, WH Wen, SY Wang, YSE Cheng, KC Tsai, ...
Journal of the American Chemical Society 133 (44), 17959-17965, 2011
|Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease|
IL Lu, N Mahindroo, PH Liang, YH Peng, CJ Kuo, KC Tsai, HP Hsieh, ...
Journal of medicinal chemistry 49 (17), 5154-5161, 2006
|Dual-wing folder radio telephone|
US Patent 7,181,253, 2007
|Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses|
WH Wen, SY Wang, KC Tsai, YSE Cheng, AS Yang, JM Fang, CH Wong
Bioorganic & medicinal chemistry 18 (11), 4074-4084, 2010
|A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies|
KC Tsai, YC Chen, NW Hsiao, CL Wang, CL Lin, YC Lee, M Li, B Wang
European journal of medicinal chemistry 45 (4), 1544-1551, 2010
|Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies|
KC Tsai, SY Chen, PH Liang, IL Lu, N Mahindroo, HP Hsieh, YS Chao, ...
Journal of medicinal chemistry 49 (12), 3485-3495, 2006
|Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease|
YM Shao, WB Yang, TH Kuo, KC Tsai, CH Lin, AS Yang, PH Liang, ...
Bioorganic & medicinal chemistry 16 (8), 4652-4660, 2008
|The pharmacophore hypotheses of IKr potassium channel blockers: novel class III antiarrhythmic agents|
LP Du, KC Tsai, MY Li, QD You, L Xia
Bioorganic & medicinal chemistry letters 14 (18), 4771-4777, 2004
|Structure and immunological characterization of the capsular polysaccharide of a pyrogenic liver abscess caused by Klebsiella pneumoniae ACTIVATION OF MACROPHAGES THROUGH TOLL …|
FL Yang, YL Yang, PC Liao, JC Chou, KC Tsai, AS Yang, F Sheu, TL Lin, ...
Journal of Biological Chemistry 286 (24), 21041-21051, 2011
|How to generate reliable and predictive CoMFA models|
L Zhang, KC Tsai, L Du, H Fang, M Li, W Xu
Current medicinal chemistry 18 (6), 923-930, 2011
|Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface|
CM Yu, HP Peng, C Chen, YC Lee, JB Chen, KC Tsai, CT Chen, ...
PloS one 7 (3), 2012
|Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq.|
SY Wang, CP Tseng, KC Tsai, CF Lin, CY Wen, HS Tsay, N Sakamoto, ...
Biochemical and biophysical research communications 385 (2), 230-235, 2009
|Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-β-Hexosaminidase Inhibitors|
CW Ho, SD Popat, TW Liu, KC Tsai, MJ Ho, WH Chen, AS Yang, CH Lin
ACS chemical biology 5 (5), 489-497, 2010
|Implementing the Fisher's Discriminant Ratio in ak-Means Clustering Algorithm for Feature Selection and Data Set Trimming|
TH Lin, HT Li, KC Tsai
Journal of chemical information and computer sciences 44 (1), 76-87, 2004
|Pharmacophore identification of α1A-adrenoceptor antagonists|
MY Li, KC Tsai, L Xia
Bioorganic & medicinal chemistry letters 15 (3), 657-664, 2005
|The effect of different electrostatic potentials on docking accuracy: a case study using DOCK5. 4|
KC Tsai, SH Wang, NW Hsiao, M Li, B Wang
Bioorganic & medicinal chemistry letters 18 (12), 3509-3512, 2008
|Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: selectivity, kinetic characterization, and molecular modeling|
SN Lo, YP Chang, KC Tsai, CY Chang, TS Wu, YF Ueng
Toxicology and applied pharmacology 272 (3), 671-680, 2013