| Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases E Schonbrunn, S Betzi, R Alam, MP Martin, A Becker, H Han, R Francis, ... Journal of medicinal chemistry 56 (10), 3768-3782, 2013 | 87 | 2013 |
| Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening TL Chiu, J Solberg, S Patil, TW Geders, X Zhang, S Rangarajan, ... Journal of chemical information and modeling 49 (12), 2726-2734, 2009 | 32 | 2009 |
| Small molecule/nucleic acid affinity chromatography: application for the identification of telomerase inhibitors which target its key RNA/DNA heteroduplex C West, R Francis, SH Friedman Bioorganic & medicinal chemistry letters 11 (20), 2727-2730, 2001 | 30 | 2001 |
| Targeting telomerase via its key RNA/DNA heteroduplex R Francis, C West, SH Friedman Bioorganic Chemistry 29 (2), 107-117, 2001 | 29 | 2001 |
| The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10 CN Paulson, K John, RM Baxley, F Kurniawan, K Orellana, R Francis, ... Open biology 9 (8), 190117, 2019 | 15 | 2019 |
| Discovery and characterization of multiple classes of human CatSper blockers EJ Carlson, R Francis, Y Liu, P Li, M Lyon, CM Santi, DJ Hook, ... ChemMedChem 17 (15), e202000499, 2022 | 14 | 2022 |
| The fungal sexual pheromone sirenin activates the human CatSper channel complex SS Syeda, EJ Carlson, MR Miller, R Francis, DE Clapham, PV Lishko, ... ACS chemical biology 11 (2), 452-459, 2016 | 14 | 2016 |
| A rapid direct telomerase assay method using 96-well streptavidin plates R Francis, SH Friedman BioTechniques 32 (5), 1154-1160, 2002 | 11 | 2002 |
| An interference-free fluorescent assay of telomerase for the high-throughput analysis of inhibitors R Francis, SH Friedman Analytical biochemistry 323 (1), 65-73, 2003 | 10 | 2003 |
| Number of lethal equivalents in human populations: how good are the previous estimates? JK Lee, M Lascoux, EV Nordheim Heredity 77 (2), 209-216, 1996 | 9 | 1996 |
| Screening through lead optimization of high affinity, allosteric cyclin-dependent kinase 2 (CDK2) inhibitors as male contraceptives that reduce sperm counts in mice EB Faber, N Wang, K John, L Sun, HL Wong, D Burban, R Francis, D Tian, ... Journal of medicinal chemistry 66 (3), 1928-1940, 2023 | 8 | 2023 |
| The discovery of high affinity and metabolically stable allosteric cyclin-dependent kinase 2 (CDK2) inhibitors from screening through lead optimization EB Faber, N Wang, K John, L Sun, D Burban, HL Wong, R Francis, D Tian, ... | | 2022 |
| CatSper as a Target for Male Contraception D Diering, E Carlson, M Miller, R Francis, J Hawkinson, P Lishko, G Georg | | 2016 |
| Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitor scaffolds using in silico and in vitro high-throughput screening methodologies TL Chiu, J Solberg, S Patil, TW Geders, X Zhang, S Rangarajan, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |
| Advancing anthrax toxin countermeasures using topomeric searching and virtual screening methodologies EA Amin, TL Chiu, DJ Hook, MA Walters, BC Finzel, J Solberg, S Patil, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |
| Discovery by high throughput screening and kinase profiling of optimized CDK2 inhibitors as male contraceptive agents R Francis, A Becker, H Han, KM Baehr, B Trinczek, R Chakrasali, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 2009 | | 2009 |
| A high throughput screening FRET assay for identification of novel anthrax toxin lethal factor inhibitors EA Amin, D Hook, S Patil, MA Walters, R Francis, TL Chiu, J Solberg, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237, 2009 | | 2009 |
| Inhibition of human telomerase by targeting its transitory RNA/DNA heteroduplex R Francis University of Missouri-Kansas City, 2005 | | 2005 |
| RNA/DNA heteroduplex as a target for telomerase inhibition. SH Friedman, R Francis ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 225, U195-U195, 2003 | | 2003 |
