| Mechanisms and Origins of Periselectivity of the Ambimodal [6+ 4] Cycloadditions of Tropone to Dimethylfulvene P Yu, TQ Chen, Z Yang, CQ He, A Patel, Y Lam, CY Liu, KN Houk Journal of the American Chemical Society 139 (24), 8251-8258, 2017 | 96 | 2017 |
| Organocatalytic [6+ 4] cycloadditions via zwitterionic intermediates: chemo-, regio-, and stereoselectivities P Yu, CQ He, A Simon, W Li, R Mose, MK Thøgersen, KA Jørgensen, ... Journal of the American Chemical Society 140 (42), 13726-13735, 2018 | 39 | 2018 |
| Model for the Enantioselectivity of Asymmetric Intramolecular Alkylations by Bis-Quaternized Cinchona Alkaloid-Derived Catalysts CQ He, A Simon, Y Lam, APJ Brunskill, N Yasuda, J Tan, AM Hyde, ... The Journal of Organic Chemistry 82 (16), 8645-8650, 2017 | 34 | 2017 |
| Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis SA Baril, AL Koenig, MW Krone, KI Albanese, CQ He, GY Lee, KN Houk, ... Journal of the American Chemical Society 139 (48), 17253-17256, 2017 | 33 | 2017 |
| Biosynthesis of thiocarboxylic acid-containing natural products LB Dong, JD Rudolf, D Kang, N Wang, CQ He, Y Deng, Y Huang, ... Nature communications 9 (1), 1-10, 2018 | 29 | 2018 |
| Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions MA Arbing, S Chan, L Harris, E Kuo, TT Zhou, CJ Ahn, L Nguyen, Q He, ... PloS one 8 (11), e81753, 2013 | 26 | 2013 |
| Design and Applications of N-tert-Butyl Sulfinyl Squaramide Catalysts Y Li, CQ He, FX Gao, Z Li, XS Xue, X Li, KN Houk, JP Cheng Organic Letters 19 (7), 1926-1929, 2017 | 24 | 2017 |
| Catalytic Effects of Ammonium and Sulfonium Salts and External Electric Fields on Aza-Diels–Alder Reactions CQ He, CC Lam, P Yu, Z Song, M Chen, Y Lam, S Chen, KN Houk The Journal of organic chemistry 85 (4), 2618-2625, 2019 | 23 | 2019 |
| Origins of regioselectivity in 1, 3-dipolar cycloadditions of nitrile oxides with alkynylboronates B Lin, P Yu, CQ He, KN Houk Bioorganic & Medicinal Chemistry 24 (20), 4787-4790, 2016 | 18 | 2016 |
| Development of a commercial manufacturing route to 2-fluoroadenine, the key unnatural nucleobase of islatravir CM Hong, Y Xu, JYL Chung, DM Schultz, M Weisel, RJ Varsolona, ... Organic Process Research & Development 25 (3), 395-404, 2020 | 17 | 2020 |
| Mechanism and Regioselectivity of an Unsymmetrical Hexadehydro-Diels–Alder (HDDA) Reaction M Chen, CQ He, KN Houk The Journal of organic chemistry 84 (4), 1959-1963, 2019 | 15 | 2019 |
| Thermodynamic consequences of Tyr to Trp mutations in the cation–π-mediated binding of trimethyllysine by the HP1 chromodomain MW Krone, KI Albanese, GO Leighton, CQ He, GY Lee, M Garcia-Borràs, ... Chemical Science 11 (13), 3495-3500, 2020 | 14 | 2020 |
| Utilizing biocatalysis and a sulfolane-mediated reductive acetal opening to access nemtabrutinib from cyrene N Kuhl, BWH Turnbull, Y Ji, RT Larson, M Shevlin, CK Prier, CK Chung, ... Green Chemistry, 2023 | 13 | 2023 |
| Analysis of laboratory-evolved flavin-dependent halogenases affords a computational model for predicting halogenase site selectivity MC Andorfer, D Evans, S Yang, CQ He, AM Girlich, J Vergara-Coll, ... Chem Catalysis 2 (10), 2658-2674, 2022 | 11 | 2022 |
| Chirality Sensing of α-Hydroxyphosphonates by N-tert-Butyl Sulfinyl Squaramide JPC Yao Li, Guo-Hui Yang, CQ He, Xin Li, KN Houk Organic Letters, 2017 | 11 | 2017 |
| Distortion, Tether, and Entropy Effects on Transannular Diels–Alder Cycloaddition Reactions of 10–18-Membered Rings CQ He, TQ Chen, A Patel, S Karabiyikoglu, CA Merlic, KN Houk The Journal of organic chemistry 80 (21), 11039-11047, 2015 | 10 | 2015 |
| Origins of Stereoselectivity in Chiral Aminoalcohol Catalysis of Oxyallyl Cation–Indole Reactions CQ He, P Yu, Y Lam, KN Houk Organic Letters 19 (20), 5685-5688, 2017 | 9 | 2017 |
| Accessing Diverse Azole Carboxylic Acid Building Blocks via Mild C–H Carboxylation: Parallel, One-Pot Amide Couplings and Machine-Learning-Guided Substrate Scope Design S Felten, CQ He, M Weisel, M Shevlin, MH Emmert Journal of the American Chemical Society, 2022 | 7 | 2022 |
| Development of a Zinc-Mediated Approach to a 2,3-cis-Pyrrolidine Arginase Inhibitor TW Lyons, TA Martinot, CQ He, J Qi, G Shao Organic Process Research & Development 24 (8), 1457-1466, 2020 | 6 | 2020 |
| Kilogram-Scale Synthesis of 2′-C-Methyl-arabino-Uridine from Uridine via Dynamic Selective Dipivaloylation JYL Chung, AM Kassim, B Simmons, TA Davis, ZJ Song, J Limanto, ... Organic Process Research & Development 26 (3), 698-709, 2021 | 5 | 2021 |
