Sebastian Brandhorst
Sebastian Brandhorst
Longevity Institute, School of Gerontology, and Department of Biological Sciences, University of
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Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ...
Cell metabolism 19 (3), 407-417, 2014
A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan
S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ...
Cell metabolism 22 (1), 86-99, 2015
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ...
Science translational medicine 4 (124), 124ra27-124ra27, 2012
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
M Wei, S Brandhorst, M Shelehchi, H Mirzaei, CW Cheng, J Budniak, ...
Science translational medicine 9 (377), eaai8700, 2017
A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms
IY Choi, L Piccio, P Childress, B Bollman, A Ghosh, S Brandhorst, ...
Cell reports 15 (10), 2136-2146, 2016
Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and-independent pathways
N Minois, D Carmona-Gutierrez, MA Bauer, P Rockenfeller, T Eisenberg, ...
Cell death & disease 3 (10), e401-e401, 2012
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity
S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ...
Cancer cell 30 (1), 136-146, 2016
Fasting enhances the response of glioma to chemo-and radiotherapy
F Safdie, S Brandhorst, M Wei, W Wang, C Lee, S Hwang, PS Conti, ...
Public Library of Science 7 (9), e44603, 2012
Fasting-mimicking diet modulates microbiota and promotes intestinal regeneration to reduce inflammatory bowel disease pathology
P Rangan, I Choi, M Wei, G Navarrete, E Guen, S Brandhorst, N Enyati, ...
Cell reports 26 (10), 2704-2719. e6, 2019
Fasting-mimicking diet and hormone therapy induce breast cancer regression
I Caffa, V Spagnolo, C Vernieri, F Valdemarin, P Becherini, M Wei, ...
Nature 583 (7817), 620-624, 2020
Safety and feasibility of fasting in combination with platinum-based chemotherapy
TB Dorff, S Groshen, A Garcia, M Shah, D Tsao-Wei, H Pham, CW Cheng, ...
BMC cancer 16, 1-9, 2016
Fasting and caloric restriction in cancer prevention and treatment
S Brandhorst, VD Longo
Metabolism in cancer, 241-266, 2016
Dietary restrictions and nutrition in the prevention and treatment of cardiovascular disease
S Brandhorst, VD Longo
Circulation research 124 (6), 952-965, 2019
Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression
S Brandhorst, M Wei, S Hwang, TE Morgan, VD Longo
Experimental gerontology 48 (10), 1120-1128, 2013
Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
M Di Tano, F Raucci, C Vernieri, I Caffa, R Buono, M Fanti, S Brandhorst, ...
Nature Communications 11 (1), 2332, 2020
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan
K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ...
Aging (Albany NY) 12 (12), 11185, 2020
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans
K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ...
Scientific reports 8 (1), 14212, 2018
Protein quantity and source, fasting-mimicking diets, and longevity
S Brandhorst, VD Longo
Advances in nutrition 10, S340-S350, 2019
Protective effects of short-term dietary restriction in surgical stress and chemotherapy
S Brandhorst, E Harputlugil, JR Mitchell, VD Longo
Ageing research reviews 39, 68-77, 2017
Time-restricted eating, intermittent fasting, and fasting-mimicking diets in weight loss
M Fanti, A Mishra, VD Longo, S Brandhorst
Current obesity reports 10, 70-80, 2021
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