Daniel J. Fazakerley
Daniel J. Fazakerley
MRC Career Development Fellow, Institute of Metabolic Science, Metabolic Research Laboratories
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2
SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ...
Cell metabolism 17 (6), 1009-1020, 2013
2962013
GLUT4 exocytosis
J Stöckli, DJ Fazakerley, DE James
Journal of cell science 124 (24), 4147-4159, 2011
2412011
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates
NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ...
Cell metabolism 22 (5), 922-935, 2015
2232015
Mapping insulin/GLUT4 circuitry
AF Rowland, DJ Fazakerley, DE James
Traffic 12 (6), 672-681, 2011
1712011
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ...
Cancer & metabolism 5 (1), 1-14, 2017
1702017
Selective insulin resistance in adipocytes
SX Tan, KH Fisher-Wellman, DJ Fazakerley, Y Ng, H Pant, J Li, CC Meoli, ...
Journal of Biological Chemistry 290 (18), 11337-11348, 2015
772015
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle
EP Taddeo, RC Laker, DS Breen, YN Akhtar, BM Kenwood, JA Liao, ...
Molecular metabolism 3 (2), 124-134, 2014
772014
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity
LE Wu, D Samocha-Bonet, PT Whitworth, DJ Fazakerley, N Turner, ...
Molecular metabolism 3 (4), 465-473, 2014
732014
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes
SX Tan, Y Ng, CC Meoli, A Kumar, PS Khoo, DJ Fazakerley, JR Junutula, ...
Journal of Biological Chemistry 287 (9), 6128-6138, 2012
682012
Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes
DJ Fazakerley, GD Holman, A Marley, DE James, J Stöckli, ACF Coster
Journal of Biological Chemistry 285 (3), 1653-1660, 2010
682010
Terminal galactosylation and sialylation switching on membrane glycoproteins upon TNF-alpha-induced insulin resistance in adipocytes
BL Parker, M Thaysen-Andersen, DJ Fazakerley, M Holliday, NH Packer, ...
Molecular & Cellular Proteomics 15 (1), 141-153, 2016
612016
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo
M Kleinert, L Sylow, DJ Fazakerley, JR Krycer, KC Thomas, AJ Oxbøll, ...
Molecular metabolism 3 (6), 630-641, 2014
562014
A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling
DJ Fazakerley, SP Lawrence, VA Lizunov, SW Cushman, GD Holman
Journal of cell science 122 (5), 727-734, 2009
552009
The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle
J Stöckli, CC Meoli, NJ Hoffman, DJ Fazakerley, H Pant, ME Cleasby, ...
Diabetes 64 (6), 1914-1922, 2015
532015
mTORC1 is a major regulatory node in the FGF21 signaling network in adipocytes
AY Minard, SX Tan, P Yang, DJ Fazakerley, W Domanova, BL Parker, ...
Cell reports 17 (1), 29-36, 2016
482016
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ...
Journal of Biological Chemistry 293 (19), 7315-7328, 2018
462018
Proteomic analysis of GLUT4 storage vesicles reveals tumor suppressor candidate 5 (TUSC5) as a novel regulator of insulin action in adipocytes
DJ Fazakerley, S Naghiloo, R Chaudhuri, F Koumanov, JG Burchfield, ...
Journal of biological chemistry 290 (39), 23528-23542, 2015
422015
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ...
Elife 7, e32111, 2018
412018
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
M Kleinert, BL Parker, R Chaudhuri, DJ Fazakerley, A Serup, KC Thomas, ...
Molecular metabolism 5 (8), 646-655, 2016
382016
Kinome screen identifies PFKFB3 and glucose metabolism as important regulators of the insulin/insulin-like growth factor (IGF)-1 signaling pathway
S Trefely, PS Khoo, JR Krycer, R Chaudhuri, DJ Fazakerley, BL Parker, ...
Journal of Biological Chemistry 290 (43), 25834-25846, 2015
382015
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Articles 1–20