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Daniel J. Fazakerley
Daniel J. Fazakerley
MRC Career Development Fellow, Institute of Metabolic Science, Metabolic Research Laboratories
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2
SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ...
Cell metabolism 17 (6), 1009-1020, 2013
4322013
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates
NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ...
Cell metabolism 22 (5), 922-935, 2015
3952015
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ...
Cancer & metabolism 5, 1-14, 2017
3442017
GLUT4 exocytosis
J Stöckli, DJ Fazakerley, DE James
Journal of cell science 124 (24), 4147-4159, 2011
3352011
Mapping insulin/GLUT4 circuitry
AF Rowland, DJ Fazakerley, DE James
Traffic 12 (6), 672-681, 2011
2042011
Muscle and adipose tissue insulin resistance: malady without mechanism?
DJ Fazakerley, JR Krycer, AL Kearney, SL Hocking, DE James
Journal of Lipid Research 60 (10), 1720-1732, 2019
1302019
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
DJ Fazakerley, AY Minard, JR Krycer, KC Thomas, J Stöckli, DJ Harney, ...
Journal of Biological Chemistry 293 (19), 7315-7328, 2018
1252018
Selective insulin resistance in adipocytes
SX Tan, KH Fisher-Wellman, DJ Fazakerley, Y Ng, H Pant, J Li, CC Meoli, ...
Journal of Biological Chemistry 290 (18), 11337-11348, 2015
1152015
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity
LE Wu, D Samocha-Bonet, PT Whitworth, DJ Fazakerley, N Turner, ...
Molecular metabolism 3 (4), 465-473, 2014
1112014
mTORC1 is a major regulatory node in the FGF21 signaling network in adipocytes
AY Minard, SX Tan, P Yang, DJ Fazakerley, W Domanova, BL Parker, ...
Cell reports 17 (1), 29-36, 2016
1102016
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ...
Elife 7, e32111, 2018
1092018
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle
EP Taddeo, RC Laker, DS Breen, YN Akhtar, BM Kenwood, JA Liao, ...
Molecular metabolism 3 (2), 124-134, 2014
1082014
Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism
SR Nagarajan, M Paul-Heng, JR Krycer, DJ Fazakerley, AF Sharland, ...
American Journal of Physiology-Endocrinology and Metabolism 316 (4), E578-E589, 2019
1032019
Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes
DJ Fazakerley, GD Holman, A Marley, DE James, J Stöckli, ACF Coster
Journal of Biological Chemistry 285 (3), 1653-1660, 2010
902010
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes
SX Tan, Y Ng, CC Meoli, A Kumar, PS Khoo, DJ Fazakerley, JR Junutula, ...
Journal of Biological Chemistry 287 (9), 6128-6138, 2012
832012
Terminal galactosylation and sialylation switching on membrane glycoproteins upon TNF-alpha-induced insulin resistance in adipocytes
BL Parker, M Thaysen-Andersen, DJ Fazakerley, M Holliday, NH Packer, ...
Molecular & Cellular Proteomics 15 (1), 141-153, 2016
822016
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ...
Nature communications 10 (1), 5486, 2019
812019
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo
M Kleinert, L Sylow, DJ Fazakerley, JR Krycer, KC Thomas, AJ Oxbøll, ...
Molecular metabolism 3 (6), 630-641, 2014
812014
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
JG Burchfield, MA Kebede, CC Meoli, J Stöckli, PT Whitworth, AL Wright, ...
Journal of biological chemistry 293 (15), 5731-5745, 2018
802018
The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle
J Stöckli, CC Meoli, NJ Hoffman, DJ Fazakerley, H Pant, ME Cleasby, ...
Diabetes 64 (6), 1914-1922, 2015
742015
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