| High-throughput screens to identify autophagy inducers that function by disrupting Beclin 1/Bcl-2 binding WC Chiang, Y Wei, YC Kuo, S Wei, A Zhou, Z Zou, J Yehl, MJ Ranaghan, ... ACS chemical biology 13 (8), 2247-2260, 2018 | 67 | 2018 |
| ADAM‐8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala271 MD Zack, AM Malfait, AP Skepner, MP Yates, DW Griggs, T Hall, RL Hills, ... Arthritis & Rheumatism 60 (9), 2704-2713, 2009 | 52 | 2009 |
| Optimizing the Cell Painting assay for image-based profiling BA Cimini, SN Chandrasekaran, M Kost-Alimova, L Miller, A Goodale, ... Nature protocols 18 (7), 1981-2013, 2023 | 49 | 2023 |
| Molecular basis for substrate recruitment to the PRMT5 methylosome KM Mulvaney, C Blomquist, N Acharya, R Li, MJ Ranaghan, M O’Keefe, ... Molecular cell 81 (17), 3481-3495. e7, 2021 | 48 | 2021 |
| Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations SN Chandrasekaran, BA Cimini, A Goodale, L Miller, M Kost-Alimova, ... Nature Methods, 1-8, 2024 | 31 | 2024 |
| Discovery of a first-in-class inhibitor of the PRMT5–substrate adaptor interaction DC McKinney, BJ McMillan, MJ Ranaghan, JA Moroco, M Brousseau, ... Journal of medicinal chemistry 64 (15), 11148-11168, 2021 | 31 | 2021 |
| Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression MM Nagiec, AP Skepner, J Negri, M Eichhorn, N Kuperwasser, E Comer, ... PLoS One 10 (3), e0120295, 2015 | 31 | 2015 |
| Functionally biased D2R antagonists: targeting the β-arrestin pathway to improve antipsychotic treatment M Weïwer, Q Xu, JP Gale, M Lewis, AJ Campbell, FA Schroeder, ... ACS chemical biology 13 (4), 1038-1047, 2018 | 30 | 2018 |
| RAPD reveals genetic similarity of Acer saccharum and Acer nigrum AP Skepner, DE Krane Heredity 80 (4), 422-428, 1998 | 28 | 1998 |
| The autophagy-related Beclin-1 protein requires the coiled-coil and BARA domains to form a homodimer with submicromolar affinity MJ Ranaghan, MA Durney, MF Mesleh, PR McCarren, CW Garvie, ... Biochemistry 56 (51), 6639-6651, 2017 | 20 | 2017 |
| Transfection of cartilage and matrices thereof in vitro D Aguiar, A Skepner, H Adkisson US Patent App. 10/891,986, 2005 | 19 | 2005 |
| Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis O Nemirovskiy, YJ Zheng, D Tung, B Korniski, S Settle, A Skepner, ... Xenobiotica 40 (8), 586-592, 2010 | 18 | 2010 |
| IGFBP-5 metabolism is disrupted in the rat medial meniscal tear model of osteoarthritis MP Yates, SL Settle, SA Yocum, P Aggarwal, LE Vickery, DJ Aguiar, ... Cartilage 1 (1), 43-54, 2010 | 9 | 2010 |
| Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells MM Nagiec, JR Duvall, AP Skepner, EA Howe, J Bastien, E Comer, ... MedChemComm 9 (11), 1831-1842, 2018 | 7 | 2018 |
| Modulators of hepatic lipoprotein metabolism MM Nagiec, JR Perez, M Palmer, A Skepner, E Comer US Patent 9,526,720, 2016 | 6 | 2016 |
| cpDNA of Acer saccharum and Acer nigrum are Very Similar AP Skepner, DE Krane | 6 | 1997 |
| nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome M Dagher, G Ongo, N Robichaud, J Kong, W Rho, I Teahulos, A Tavakoli, ... bioRxiv, 2023.04. 17.535914, 2023 | 5 | 2023 |
| Abstract P158: Hepatic Trib1 Induces Proteosome-dependent Degradation Of C/ebpα In A Cop1-And Stk40-Dependent Manner CV Matias, KS Jadhav, EH Ha, M Nagiec, AP Skepner, RK Soni, ... Arteriosclerosis, Thrombosis, and Vascular Biology 41 (Suppl_1), AP158-AP158, 2021 | | 2021 |
| The Autophagy-Related Beclin-1 Protein Requires both the Coiled-Coil and Bara Domains to form a Homodimer with Sub-Micromolar Affinity M Ranaghan, M Durney, M Mesleh, P McCarren, C Garvie, D Daniels, ... PROTEIN SCIENCE 27, 46-46, 2018 | | 2018 |
| Reprogramming of hepatic lipoprotein metabolism by small molecule inducers of TRIB1 expression (998.1) M Nagiec, A Skepner, J Negri, M Eichhorn, E Comer, G Muncipinto, ... The FASEB Journal 28, 998.1, 2014 | | 2014 |
