James N. Sleigh
Title
Cited by
Cited by
Year
The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy
JN Sleigh, TH Gillingwater, K Talbot
Disease models & mechanisms 4 (4), 457-467, 2011
1102011
Conserved genes act as modifiers of invertebrate SMN loss of function defects
M Dimitriadi, JN Sleigh, A Walker, HC Chang, A Sen, G Kalloo, J Harris, ...
PLoS Genet 6 (10), e1001172, 2010
942010
Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy
SM Hammond, G Hazell, F Shabanpoor, AF Saleh, M Bowerman, ...
Proceedings of the National Academy of Sciences 113 (39), 10962-10967, 2016
922016
Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy
JN Sleigh, A Barreiro-Iglesias, PL Oliver, A Biba, T Becker, KE Davies, ...
Human molecular genetics 23 (4), 855-869, 2014
602014
A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform …
JN Sleigh, SD Buckingham, B Esmaeili, M Viswanathan, E Cuppen, ...
Human molecular genetics 20 (2), 245-260, 2011
562011
A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia
JN Sleigh, GA Weir, G Schiavo
BMC research notes 9 (1), 1-7, 2016
522016
Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot–Marie–Tooth type 2D mice
JN Sleigh, SJ Grice, RW Burgess, K Talbot, MZ Cader
Human molecular genetics 23 (10), 2639-2650, 2014
512014
Vascular defects and spinal cord hypoxia in spinal muscular atrophy
E Somers, RD Lees, K Hoban, JN Sleigh, H Zhou, F Muntoni, K Talbot, ...
Annals of neurology 79 (2), 217-230, 2016
502016
Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles
JN Sleigh, RW Burgess, TH Gillingwater, MZ Cader
Journal of neuroscience methods 227, 159-165, 2014
482014
Synaptic deficits at neuromuscular junctions in two mouse models of Charcot–Marie–Tooth type 2d
EL Spaulding, JN Sleigh, KH Morelli, MJ Pinter, RW Burgess, KL Seburn
Journal of Neuroscience 36 (11), 3254-3267, 2016
422016
Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice
BJ Turner, N Alfazema, RK Sheean, JN Sleigh, KE Davies, MK Horne, ...
Neurobiology of aging 35 (4), 906-915, 2014
382014
Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations
JN Sleigh, JM Dawes, SJ West, N Wei, EL Spaulding, A Gómez-Martín, ...
Proceedings of the National Academy of Sciences 114 (16), E3324-E3333, 2017
372017
Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology
SJ Grice, JN Sleigh, WW Motley, JL Liu, RW Burgess, K Talbot, MZ Cader
Human molecular genetics 24 (15), 4397-4406, 2015
362015
Loss of Lrsam1, a Charcot-Marie-Tooth disease-associated E3 ubiquitin ligase, sensitizes peripheral axons to degeneration in mice
LP Bogdanik, JN Sleigh, C Tian, ME Samuels, K Bedard, KL Seburn, ...
Disease Models & Mechanisms, dmm. 010942, 2013
36*2013
In vivo imaging of axonal transport in murine motor and sensory neurons
KL Gibbs, B Kalmar, JN Sleigh, L Greensmith, G Schiavo
Journal of Neuroscience Methods 257, 26-33, 2016
312016
Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics
SJ Grice, JN Sleigh, JL Liu, DB Sattelle
Bioessays 33 (12), 956-965, 2011
262011
Axonal transport and neurological disease
JN Sleigh, AM Rossor, AD Fellows, AP Tosolini, G Schiavo
Nature Reviews Neurology, 1-13, 2019
232019
Motor neuron gene therapy: lessons from spinal muscular atrophy for amyotrophic lateral sclerosis
AP Tosolini, JN Sleigh
Frontiers in molecular neuroscience 10, 405, 2017
232017
Methodological advances in imaging intravital axonal transport
JN Sleigh, A Vagnoni, AE Twelvetrees, G Schiavo
F1000Research 6, 2017
202017
Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition
AL Kalinski, AN Kar, J Craver, AP Tosolini, JN Sleigh, SJ Lee, ...
Journal of Cell Biology 218 (6), 1871-1890, 2019
192019
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Articles 1–20