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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. M Oft, J Peli, C Rudaz, H Schwarz, H Beug, E Reichmann Genes & development 10 (19), 2462-2477, 1996 | 863 | 1996 |
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis M Oft, KH Heider, H Beug Current Biology 8 (23), 1243-1252, 1998 | 847 | 1998 |
Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor D Parry, T Guzi, F Shanahan, N Davis, D Prabhavalkar, D Wiswell, ... Molecular cancer therapeutics 9 (8), 2344-2353, 2010 | 576 | 2010 |
IL-10 elicits IFNγ-dependent tumor immune surveillance JB Mumm, J Emmerich, X Zhang, I Chan, L Wu, S Mauze, S Blaisdell, ... Cancer cell 20 (6), 781-796, 2011 | 465 | 2011 |
Metastasis is driven by sequential elevation of H-ras and Smad2 levels M Oft, RJ Akhurst, A Balmain Nature cell biology 4 (7), 487-494, 2002 | 418 | 2002 |
IL-10: master switch from tumor-promoting inflammation to antitumor immunity M Oft Cancer immunology research 2 (3), 194-199, 2014 | 300 | 2014 |
IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without De Novo Infiltration from Secondary Lymphoid Organs J Emmerich, JB Mumm, IH Chan, D LaFace, H Truong, T McClanahan, ... Cancer research 72 (14), 3570-3581, 2012 | 295 | 2012 |
TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest C Petritsch, H Beug, A Balmain, M Oft Genes & development 14 (24), 3093-3101, 2000 | 292 | 2000 |
Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A D Bevec, H Jaksche, M Oft, T Wöhl, M Himmelspach, A Pacher, ... Science 271 (5257), 1858-1860, 1996 | 283 | 1996 |
Safety, antitumor activity, and immune activation of pegylated recombinant human interleukin-10 (AM0010) in patients with advanced solid tumors A Naing, KP Papadopoulos, KA Autio, PA Ott, MR Patel, DJ Wong, ... Journal of Clinical Oncology 34 (29), 3562, 2016 | 232 | 2016 |
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer NR Blatner, MF Mulcahy, KL Dennis, D Scholtens, DJ Bentrem, ... Science translational medicine 4 (164), 164ra159-164ra159, 2012 | 224 | 2012 |
PEGylated IL-10 (Pegilodecakin) induces systemic immune activation, CD8+ T cell invigoration and polyclonal T cell expansion in cancer patients A Naing, JR Infante, KP Papadopoulos, IH Chan, C Shen, NP Ratti, ... Cancer Cell 34 (5), 775-791. e3, 2018 | 219 | 2018 |
The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions. I Fialka, H Schwarz, E Reichmann, M Oft, M Busslinger, H Beug The Journal of cell biology 132 (6), 1115-1132, 1996 | 206 | 1996 |
Swords into plowshares: IL-23 repurposes tumor immune surveillance JL Langowski, RA Kastelein, M Oft Trends in immunology 28 (5), 207-212, 2007 | 180 | 2007 |
IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis MWL Teng, DM Andrews, N McLaughlin, B Von Scheidt, SF Ngiow, ... Proceedings of the National Academy of Sciences 107 (18), 8328-8333, 2010 | 153 | 2010 |
Cytokine-based transformation of immune surveillance into tumor-promoting inflammation JB Mumm, M Oft Oncogene 27 (45), 5913-5919, 2008 | 151 | 2008 |
Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5 O Schatz, M Oft, C Dascher, M Schebesta, O Rosorius, H Jaksche, ... Proceedings of the National Academy of Sciences 95 (4), 1607-1612, 1998 | 116 | 1998 |
Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial A Naing, DJ Wong, JR Infante, WM Korn, R Aljumaily, KP Papadopoulos, ... The Lancet Oncology 20 (11), 1544-1555, 2019 | 94 | 2019 |
Functional analysis of the human immunodeficiency virus type 1 Rev protein oligomerization interface SL Thomas, M Oft, H Jaksche, G Casari, P Heger, M Dobrovnik, D Bevec, ... Journal of virology 72 (4), 2935-2944, 1998 | 90 | 1998 |