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Fabrizio Facchinetti
Fabrizio Facchinetti
Chiesi Farmaceutici S.p.A., Corporate Preclinical R&D, Parma, Italy
Verified email at chiesi.com
Title
Cited by
Cited by
Year
Free radicals as mediators of neuronal injury
F Facchinetti, VL Dawson, TM Dawson
Cellular and molecular neurobiology 18, 667-682, 1998
4051998
Cannabinoids ablate release of TNFα in rat microglial cells stimulated with lypopolysaccharide
F Facchinetti, E Del Giudice, S Furegato, M Passarotto, A Leon
Glia 41 (2), 161-168, 2003
3402003
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation
R Nassini, P Pedretti, N Moretto, C Fusi, C Carnini, F Facchinetti, ...
Public Library of Science 7 (8), e42454, 2012
2402012
α, β-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages
F Facchinetti, F Amadei, P Geppetti, F Tarantini, C Di Serio, A Dragotto, ...
American journal of respiratory cell and molecular biology 37 (5), 617-623, 2007
2362007
Synthesis and Biological Activity of Flurbiprofen Analogues as Selective Inhibitors of β-Amyloid1-42 Secretion
I Peretto, S Radaelli, C Parini, M Zandi, LF Raveglia, G Dondio, ...
Journal of Medicinal Chemistry 48 (18), 5705-5720, 2005
1672005
α, β-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases
N Moretto, F Facchinetti, T Southworth, M Civelli, D Singh, R Patacchini
American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (5 …, 2009
1442009
Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase
AF Samdani, C Newcamp, A Resink, F Facchinetti, BE Hoffman, ...
Journal of Neuroscience 17 (12), 4633-4641, 1997
1221997
CHF5074, a novel γ‐secretase modulator, attenuates brain β‐amyloid pathology and learning deficit in a mouse model of Alzheimer's disease
BP Imbimbo, B Hutter‐Paier, G Villetti, F Facchinetti, V Cenacchi, R Volta, ...
British journal of pharmacology 156 (6), 982-993, 2009
1032009
Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis
F Facchinetti, M Sasaki, FB Cutting, JE Macdonald, D Reif, MF Beal, ...
Neuroscience 90 (4), 1483-1492, 1999
1031999
Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells
N Moretto, S Bertolini, C Iadicicco, G Marchini, M Kaur, G Volpi, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 303 …, 2012
1012012
Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease
N Moretto, G Volpi, F Pastore, F Facchinetti
Annals of the New York Academy of Sciences 1259 (1), 39-46, 2012
972012
Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801
F Facchinetti, E Ciani, R Dall'Olio, M Virgili, A Contestabile, F Fonnum
Developmental brain research 74 (2), 219-224, 1993
971993
1-(3′, 4′-Dichloro-2-fluoro [1, 1′-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel γ-secretase modulator, reduces brain β-amyloid pathology in a transgenic …
BP Imbimbo, E Del Giudice, D Colavito, A D'Arrigo, M Dalle Carbonare, ...
Journal of Pharmacology and Experimental Therapeutics 323 (3), 822-830, 2007
882007
Cigarette smoke and α, β‐unsaturated aldehydes elicit VEGF release through the p38 MAPK pathway in human airway smooth muscle cells and lung fibroblasts
G Volpi, F Facchinetti, N Moretto, M Civelli, R Patacchini
British journal of pharmacology 163 (3), 649-661, 2011
722011
CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration
N Moretto, P Caruso, R Bosco, G Marchini, F Pastore, E Armani, G Amari, ...
Journal of Pharmacology and Experimental Therapeutics 352 (3), 559-567, 2015
702015
H2O2 induces upregulation of Fas and Fas ligand expression in NGF‐differentiated PC12 cells: Modulation by cAMP
F Facchinetti, S Furegato, S Terrazzino, A Leon
Journal of neuroscience research 69 (2), 178-188, 2002
692002
Melatonin as an adjunct to therapeutic hypothermia in a piglet model of neonatal encephalopathy: a translational study
NJ Robertson, K Martinello, I Lingam, A Avdic-Belltheus, C Meehan, ...
Neurobiology of disease 121, 240-251, 2019
612019
In vitro and in vivo profiling of CHF5022 and CHF5074: Two β-amyloid1–42 lowering agents
BP Imbimbo, E Del Giudice, V Cenacchi, R Volta, G Villetti, F Facchinetti, ...
Pharmacological research 55 (4), 318-328, 2007
602007
Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells
E Del Giudice, L Rinaldi, M Passarotto, F Facchinetti, A D’Arrigo, A Guiotto, ...
Journal of Leucocyte Biology 81 (6), 1512-1522, 2007
592007
Novel class of benzoic acid ester derivatives as potent PDE4 inhibitors for inhaled administration in the treatment of respiratory diseases
E Armani, G Amari, A Rizzi, RD Fanti, E Ghidini, C Capaldi, L Carzaniga, ...
Journal of Medicinal Chemistry 57 (3), 793-816, 2014
482014
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