| Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect DA Scott, AD Richardson, FV Filipp, CA Knutzen, GG Chiang, AR Ze'ev, ... Journal of Biological Chemistry 286 (49), 42626-42634, 2011 | 411 | 2011 |
| Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells FV Filipp, DA Scott, ZA Ronai, AL Osterman, JW Smith Pigment cell & melanoma research 25 (3), 375-383, 2012 | 215 | 2012 |
| Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p WA Stanley, FV Filipp, P Kursula, N Schüller, R Erdmann, W Schliebs, ... Molecular cell 24 (5), 653-663, 2006 | 205 | 2006 |
| Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities NJ Lanning, JP Castle, SJ Singh, AN Leon, EA Tovar, A Sanghera, ... Cancer & metabolism 5, 1-14, 2017 | 179 | 2017 |
| Determinants of conformational dimerization of Mad2 and its inhibition by p31comet M Mapelli, FV Filipp, G Rancati, L Massimiliano, L Nezi, G Stier, ... The EMBO journal 25 (6), 1273-1284, 2006 | 167 | 2006 |
| Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines S Wilson, J Qi, FV Filipp Scientific reports 6 (1), 32611, 2016 | 141 | 2016 |
| Glutamine‐fueled mitochondrial metabolism is decoupled from glycolysis in melanoma FV Filipp, B Ratnikov, J De Ingeniis, JW Smith, AL Osterman, DA Scott Pigment cell & melanoma research 25 (6), 732-739, 2012 | 129 | 2012 |
| Topography for independent binding of α-helical and PPII-helical ligands to a peroxisomal SH3 domain A Douangamath, FV Filipp, ATJ Klein, P Barnett, P Zou, T Voorn-Brouwer, ... Molecular cell 10 (5), 1007-1017, 2002 | 118 | 2002 |
| Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19 C Neufeld, FV Filipp, B Simon, A Neuhaus, N Schüller, C David, ... The EMBO Journal 28 (6), 745-754, 2009 | 110 | 2009 |
| Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma J Guan, R Gupta, FV Filipp Scientific reports 5 (1), 7857, 2015 | 108 | 2015 |
| The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells S Wilson, L Fan, N Sahgal, J Qi, FV Filipp Oncotarget 8 (18), 30328, 2017 | 100 | 2017 |
| Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis RH Kimura, L Wang, B Shen, L Huo, W Tummers, FV Filipp, HH Guo, ... Nature communications 10 (1), 4673, 2019 | 99 | 2019 |
| Cistromic reprogramming of the diurnal glucocorticoid hormone response by high-fat diet F Quagliarini, AA Mir, K Balazs, M Wierer, KA Dyar, C Jouffe, K Makris, ... Molecular cell 76 (4), 531-545. e5, 2019 | 85 | 2019 |
| Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes JC Tiffen, D Gunatilake, SJ Gallagher, K Gowrishankar, A Heinemann, ... Oncotarget 6 (29), 27023, 2015 | 81 | 2015 |
| Opportunities for artificial intelligence in advancing precision medicine FV Filipp Current genetic medicine reports 7 (4), 208-213, 2019 | 77 | 2019 |
| Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator FV Filipp Journal of carcinogenesis 12, 2013 | 66 | 2013 |
| EZH2 cooperates with DNA methylation to downregulate key tumor suppressors and IFN gene signatures in melanoma J Tiffen, SJ Gallagher, F Filipp, D Gunatilake, A Al Emran, C Cullinane, ... Journal of Investigative Dermatology 140 (12), 2442-2454. e5, 2020 | 54 | 2020 |
| Precision medicine driven by cancer systems biology FV Filipp Cancer and Metastasis Reviews 36, 91-108, 2017 | 54 | 2017 |
| Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis DC Zielinski, FV Filipp, A Bordbar, K Jensen, JW Smith, MJ Herrgard, ... Nature communications 6 (1), 7101, 2015 | 54 | 2015 |
| Is science killing sport? Gene therapy and its possible abuse in doping F Filipp EMBO reports 8 (5), 433-435, 2007 | 54 | 2007 |
