Derek Laver
Derek Laver
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Cited by
Cited by
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans
H Watanabe, N Chopra, D Laver, HS Hwang, SS Davies, DE Roach, ...
Nature medicine 15 (4), 380-383, 2009
Calsequestrin and the calcium release channel of skeletal and cardiac muscle
NA Beard, DR Laver, AF Dulhunty
Progress in biophysics and molecular biology 85 (1), 33-69, 2004
Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanisms
DR Laver, TM Baynes, AF Dulhunty
The Journal of membrane biology 156 (3), 213-229, 1997
Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass
FA Hilliard, DS Steele, D Laver, Z Yang, SJ Le Marchand, N Chopra, ...
Journal of molecular and cellular cardiology 48 (2), 293-301, 2010
Ca2+ stores regulate ryanodine receptor Ca2+ release channels via luminal and cytosolic Ca2+ sites
DR Laver
Biophysical journal 92 (10), 3541-3555, 2007
Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channels
NA Beard, MM Sakowska, AF Dulhunty, DR Laver
Biophysical journal 82 (1), 310-320, 2002
Cytoplasmic Ca 2+ inhibits the ryanodine receptor from cardiac muscle
DR Laver, LD Roden, GP Ahern, KR Eager, PR Junankar, AF Dulhunty
The Journal of membrane biology 147 (1), 7-22, 1995
Inhibition of Cardiac Ca2+ Release Channels (RyR2) Determines Efficacy of Class I Antiarrhythmic Drugs in Catecholaminergic Polymorphic Ventricular Tachycardia
HS Hwang, C Hasdemir, D Laver, D Mehra, K Turhan, M Faggioni, H Yin, ...
Circulation: Arrhythmia and Electrophysiology 4 (2), 128-135, 2011
Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation
NA Beard, MG Casarotto, L Wei, M Varsányi, DR Laver, AF Dulhunty
Biophysical journal 88 (5), 3444-3454, 2005
Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia
DR Laver, VJ Owen, PR Junankar, NL Taske, AF Dulhunty, GD Lamb
Biophysical journal 73 (4), 1913-1924, 1997
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants
HS Hwang, FR Nitu, Y Yang, K Walweel, L Pereira, CN Johnson, ...
Circulation research 114 (7), 1114-1124, 2014
Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle
AF Dulhunty, CS Haarmann, D Green, DR Laver, PG Board, ...
Progress in biophysics and molecular biology 79 (1-3), 45-75, 2002
Activation and inhibition of skeletal RyR channels by a part of the skeletal DHPR II-III loop: effects of DHPR Ser687 and FKBP12
AF Dulhunty, DR Laver, EM Gallant, MG Casarotto, SM Pace, S Curtis
Biophysical Journal 77 (1), 189-203, 1999
Regulation of the calcium release channel from rabbit skeletal muscle by the nucleotides ATP, AMP, IMP and adenosine
DR Laver, GKE Lenz, GD Lamb
The Journal of physiology 537 (3), 763-778, 2001
Luminal Ca2+–regulated Mg2+ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters
DR Laver, ER O'Neill, GD Lamb
The Journal of general physiology 124 (6), 741-758, 2004
Control of sarcoplasmic reticulum Ca2+ release by stochastic RyR gating within a 3D model of the cardiac dyad and importance of induction decay for CICR termination
MB Cannell, CHT Kong, MS Imtiaz, DR Laver
Biophysical journal 104 (10), 2149-2159, 2013
Termination of calcium-induced calcium release by induction decay: an emergent property of stochastic channel gating and molecular scale architecture
DR Laver, CHT Kong, MS Imtiaz, MB Cannell
Journal of molecular and cellular cardiology 54, 98-100, 2013
Inactivation of Ca2+ release channels (ryanodine receptors RyR1 and RyR2) with rapid steps in [Ca2+] and voltage
DR Laver, GD Lamb
Biophysical Journal 74 (5), 2352-2364, 1998
Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle
JI Kourie, DR Laver, PR Junankar, PW Gage, AF Dulhunty
Biophysical journal 70 (1), 202-221, 1996
Generation and propagation of gastric slow waves
DF Van Helden, DR Laver, J Holdsworth, MS Imtiaz
Clinical and Experimental Pharmacology and Physiology 37 (4), 516-524, 2010
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