Segui
Christoph Licht
Christoph Licht
The Hospital for Sick Children: Division of Nephrology & Cell Biology Program; University of Toronto
Email verificata su sickkids.ca
Titolo
Citata da
Citata da
Anno
Terminal complement inhibitor eculizumab in atypical hemolytic–uremic syndrome
CM Legendre, C Licht, P Muus, LA Greenbaum, S Babu, C Bedrosian, ...
New England Journal of Medicine 368 (23), 2169-2181, 2013
16092013
An international consensus approach to the management of atypical hemolytic uremic syndrome in children
C Loirat, F Fakhouri, G Ariceta, N Besbas, M Bitzan, A Bjerre, R Coppo, ...
Pediatric nephrology 31, 15-39, 2016
6612016
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes”(KDIGO) Controversies Conference
THJ Goodship, HT Cook, F Fakhouri, FC Fervenza, V Frémeaux-Bacchi, ...
Kidney international 91 (3), 539-551, 2017
6492017
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test
AC Lionel, G Costain, N Monfared, S Walker, MS Reuter, SM Hosseini, ...
Genetics in Medicine 20 (4), 435-443, 2018
5172018
Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome
G Ariceta, N Besbas, S Johnson, D Karpman, D Landau, C Licht, C Loirat, ...
Pediatric nephrology 24, 687-696, 2009
4862009
Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies
C Licht, LA Greenbaum, P Muus, S Babu, CL Bedrosian, DJ Cohen, ...
Kidney international 87 (5), 1061-1073, 2015
4482015
Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency
M Józsi, C Licht, S Strobel, SLH Zipfel, H Richter, S Heinen, PF Zipfel, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1512-1514, 2008
3902008
Deletion of Complement Factor H–Related Genes CFHR1 and CFHR3 Is Associated with Atypical Hemolytic Uremic Syndrome
PF Zipfel, M Edey, S Heinen, M Józsi, H Richter, J Misselwitz, B Hoppe, ...
PLoS genetics 3 (3), e41, 2007
3842007
Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy
O Gross, C Licht, HJ Anders, B Hoppe, B Beck, B Tönshoff, B Höcker, ...
Kidney international 81 (5), 494-501, 2012
3732012
New approaches to the treatment of dense deposit disease
RJH Smith, J Alexander, PN Barlow, M Botto, TL Cassavant, HT Cook, ...
Journal of the American Society of Nephrology 18 (9), 2447-2456, 2007
3312007
Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome
LA Greenbaum, M Fila, G Ardissino, SI Al-Akash, J Evans, P Henning, ...
Kidney international 89 (3), 701-711, 2016
2852016
Abnormalities in the alternative pathway of complement in children with hematopoietic stem cell transplant-associated thrombotic microangiopathy
S Jodele, C Licht, J Goebel, BP Dixon, K Zhang, TA Sivakumaran, ...
Blood, The Journal of the American Society of Hematology 122 (12), 2003-2007, 2013
2642013
Eculizumab therapy in children with severe hematopoietic stem cell transplantation–associated thrombotic microangiopathy
S Jodele, T Fukuda, A Vinks, K Mizuno, BL Laskin, J Goebel, BP Dixon, ...
Biology of Blood and Marrow Transplantation 20 (4), 518-525, 2014
2502014
Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)
C Licht, S Heinen, M Jozsi, I Löschmann, RE Saunders, SJ Perkins, ...
Kidney international 70 (1), 42-50, 2006
2472006
aHUS caused by complement dysregulation: new therapies on the horizon
AM Waters, C Licht
Pediatric Nephrology 26, 41-57, 2011
1972011
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration
X Zhan, DE Larson, C Wang, DC Koboldt, YV Sergeev, RS Fulton, ...
Nature genetics 45 (11), 1375-1379, 2013
1892013
Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative
CE Kashtan, J Ding, M Gregory, O Gross, L Heidet, B Knebelmann, ...
Pediatric nephrology 28, 5-11, 2013
1742013
Outrageous prices of orphan drugs: a call for collaboration
L Luzzatto, HI Hyry, A Schieppati, E Costa, S Simoens, F Schaefer, ...
The Lancet 392 (10149), 791-794, 2018
1682018
Spectrum of complement-mediated thrombotic microangiopathies: pathogenetic insights identifying novel treatment approaches
M Riedl, F Fakhouri, M Le Quintrec, DG Noone, TC Jungraithmayr, ...
Seminars in thrombosis and hemostasis 40 (04), 444-464, 2014
1612014
Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions
M Józsi, S Heinen, A Hartmann, CW Ostrowicz, S Hälbich, H Richter, ...
Journal of the American Society of Nephrology 17 (1), 170-177, 2006
1592006
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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