Christoph Handschin
Christoph Handschin
University of Basel, Biozentrum
Email verificata su - Home page
Citata da
Citata da
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
S Jger, C Handschin, JS Pierre, BM Spiegelman
Proceedings of the National Academy of Sciences 104 (29), 12017-12022, 2007
Metabolic control through the PGC-1 family of transcription coactivators
J Lin, C Handschin, BM Spiegelman
Cell metabolism 1 (6), 361-370, 2005
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
J St-Pierre, S Drori, M Uldry, JM Silvaggi, J Rhee, S Jger, C Handschin, ...
Cell 127 (2), 397-408, 2006
The role of exercise and PGC1α in inflammation and chronic disease
C Handschin, BM Spiegelman
Nature 454 (7203), 463-469, 2008
Peroxisome proliferator-activated receptor γ coactivator 1 coactivators, energy homeostasis, and metabolism
C Handschin, BM Spiegelman
Endocrine reviews 27 (7), 728-735, 2006
PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
M Sandri, J Lin, C Handschin, W Yang, ZP Arany, SH Lecker, ...
Proceedings of the National Academy of Sciences 103 (44), 16260-16265, 2006
An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle
C Handschin, J Rhee, J Lin, PT Tarr, BM Spiegelman
Proceedings of the national academy of sciences 100 (12), 7111-7116, 2003
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
VK Mootha, C Handschin, D Arlow, X Xie, JS Pierre, S Sihag, W Yang, ...
Proceedings of the National Academy of Sciences 101 (17), 6570-6575, 2004
Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle
Z Arany, H He, J Lin, K Hoyer, C Handschin, O Toka, F Ahmad, T Matsui, ...
Cell metabolism 1 (4), 259-271, 2005
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP
J Lin, R Yang, PT Tarr, PH Wu, C Handschin, S Li, W Yang, L Pei, M Uldry, ...
Cell 120 (2), 261-273, 2005
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
C Handschin, S Chin, P Li, F Liu, E Maratos-Flier, NK LeBrasseur, Z Yan, ...
Journal of Biological Chemistry 282 (41), 30014-30021, 2007
Induction of drug metabolism: the role of nuclear receptors
C Handschin, UA Meyer
Pharmacological reviews 55 (4), 649-673, 2003
Abnormal glucose homeostasis in skeletal muscle–specific PGC-1α knockout mice reveals skeletal muscle–pancreatic β cell crosstalk
C Handschin, CS Choi, S Chin, S Kim, D Kawamori, AJ Kurpad, ...
The Journal of clinical investigation 117 (11), 3463-3474, 2007
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK
M Fan, J Rhee, J St-Pierre, C Handschin, P Puigserver, J Lin, S Jeger, ...
Genes & development 18 (3), 278-289, 2004
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α
C Handschin, J Lin, J Rhee, AK Peyer, S Chin, PH Wu, UA Meyer, ...
Cell 122 (4), 505-515, 2005
PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
C Handschin, YM Kobayashi, S Chin, P Seale, KP Campbell, ...
Genes & development 21 (7), 770-783, 2007
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells
Z Wu, X Huang, Y Feng, C Handschin, Y Feng, PS Gullicksen, O Bare, ...
Proceedings of the National Academy of Sciences 103 (39), 14379-14384, 2006
Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
CS Choi, DE Befroy, R Codella, S Kim, RM Reznick, YJ Hwang, ZX Liu, ...
Proceedings of the National Academy of Sciences 105 (50), 19926-19931, 2008
Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise
S Schnyder, C Handschin
Bone 80, 115-125, 2015
NUBIScan, an in Silico Approach for Prediction of Nuclear Receptor Response Elements
M Podvinec, MR Kaufmann, C Handschin, UA Meyer
Molecular Endocrinology 16 (6), 1269-1279, 2002
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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