| Wisdom of crowds for robust gene network inference D Marbach, JC Costello, R Küffner, NM Vega, RJ Prill, DM Camacho, ... Nature methods 9 (8), 796-804, 2012 | 1621 | 2012 |
| Inferring regulatory networks from expression data using tree-based methods VA Huynh-Thu, A Irrthum, L Wehenkel, P Geurts PloS one 5 (9), e12776, 2010 | 1427 | 2010 |
| Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B S Hanks, K Coleman, S Reid, A Plaja, H Firth, D FitzPatrick, A Kidd, ... Nature genetics 36 (11), 1159-1161, 2004 | 661 | 2004 |
| Clinical management of breast cancer heterogeneity D Zardavas, A Irrthum, C Swanton, M Piccart Nature reviews Clinical oncology 12 (7), 381-394, 2015 | 478 | 2015 |
| Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase A Irrthum, MJ Karkkainen, K Devriendt, K Alitalo, M Vikkula The American Journal of Human Genetics 67 (2), 295-301, 2000 | 478 | 2000 |
| Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia A Irrthum, K Devriendt, D Chitayat, G Matthijs, C Glade, PM Steijlen, ... The American Journal of Human Genetics 72 (6), 1470-1478, 2003 | 455 | 2003 |
| Genotype-phenotype associations in Sotos syndrome: an analysis of 266 individuals with NSD1 aberrations K Tatton-Brown, J Douglas, K Coleman, G Baujat, TRP Cole, S Das, ... The American Journal of Human Genetics 77 (2), 193-204, 2005 | 327 | 2005 |
| Supervised learning with decision tree-based methods in computational and systems biology P Geurts, A Irrthum, L Wehenkel Molecular Biosystems 5 (12), 1593-1605, 2009 | 235 | 2009 |
| A gene for inherited cutaneous venous anomalies (“glomangiomas”) localizes to chromosome 1p21-22 LM Boon, P Brouillard, A Irrthum, L Karttunen, ML Warman, R Rudolph, ... The American Journal of Human Genetics 65 (1), 125-133, 1999 | 184 | 1999 |
| MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets N Garbacki, E Di Valentin, VA Huynh-Thu, P Geurts, A Irrthum, C Crahay, ... PloS one 6 (1), e16509, 2011 | 171 | 2011 |
| Hereditary cutaneomucosal venous malformations are caused by TIE2 mutations with widely variable hyper-phosphorylating effects V Wouters, N Limaye, M Uebelhoer, A Irrthum, LM Boon, JB Mulliken, ... European Journal of Human Genetics 18 (4), 414-420, 2010 | 162 | 2010 |
| Mutations in the VEGFR3 signaling pathway explain 36% of familial lymphedema A Mendola, MJ Schlögel, A Ghalamkarpour, A Irrthum, HL Nguyen, ... Molecular syndromology 4 (6), 257-266, 2013 | 99 | 2013 |
| The AURORA initiative for metastatic breast cancer D Zardavas, M Maetens, A Irrthum, T Goulioti, K Engelen, D Fumagalli, ... British journal of cancer 111 (10), 1881-1887, 2014 | 89 | 2014 |
| Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis C Josse, N Bouznad, P Geurts, A Irrthum, VA Huynh-Thu, L Servais, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (3 …, 2014 | 76 | 2014 |
| Multiple mechanisms are implicated in the generation of 5q35 microdeletions in Sotos syndrome K Tatton-Brown, J Douglas, K Coleman, G Baujat, K Chandler, A Clarke, ... Journal of medical genetics 42 (4), 307-313, 2005 | 74 | 2005 |
| Myelin-derived lipids modulate macrophage activity by liver X receptor activation JFJ Bogie, S Timmermans, VA Huynh-Thu, A Irrthum, HJM Smeets, ... Public Library of Science 7 (9), e44998, 2012 | 61 | 2012 |
| Partial NSD1 deletions cause 5% of Sotos syndrome and are readily identifiable by multiplex ligation dependent probe amplification J Douglas, K Tatton-Brown, K Coleman, S Guerrero, J Berg, TRP Cole, ... Journal of Medical Genetics 42 (9), e56-e56, 2005 | 53 | 2005 |
| Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening InitiativeGenomics and … P Aftimos, M Oliveira, A Irrthum, D Fumagalli, C Sotiriou, EN Gal-Yam, ... Cancer discovery 11 (11), 2796-2811, 2021 | 42 | 2021 |
| Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC A Irrthum, P Brouillard, O Enjolras, NF Gibbs, LF Eichenfield, BR Olsen, ... European Journal of Human Genetics 9 (1), 34-38, 2001 | 42 | 2001 |
| First report of AURORA, the breast international group (BIG) molecular screening initiative for metastatic breast cancer (MBC) patients (pts) PG Aftimos, AMADM e Oliveira, F Hilbers, D Venet, A Vingiani, ENG Yam, ... Annals of Oncology 30, iii48, 2019 | 10 | 2019 |
