|PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer|
J Li, C Yen, D Liaw, K Podsypanina, S Bose, SI Wang, J Puc, C Miliaresis, ...
science 275 (5308), 1943-1947, 1997
|Strong association of de novo copy number mutations with autism|
J Sebat, B Lakshmi, D Malhotra, J Troge, C Lese-Martin, T Walsh, ...
Science 316 (5823), 445-449, 2007
|Large-scale copy number polymorphism in the human genome|
J Sebat, B Lakshmi, J Troge, J Alexander, J Young, P Lundin, S Månér, ...
Science 305 (5683), 525-528, 2004
|Tumour evolution inferred by single-cell sequencing|
N Navin, J Kendall, J Troge, P Andrews, L Rodgers, J McIndoo, K Cook, ...
Nature 472 (7341), 90, 2011
|Circular binary segmentation for the analysis of array‐based DNA copy number data|
AB Olshen, ES Venkatraman, R Lucito, M Wigler
Biostatistics 5 (4), 557-572, 2004
|Cloning the differences between two complex genomes|
N Lisitsyn, M Wigler
Science 259 (5097), 946-951, 1993
|Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells|
M Wigler, S Silverstein, LS Lee, A Pellicer, Y Cheng, R Axel
Cell 11 (1), 223-232, 1977
|The contribution of de novo coding mutations to autism spectrum disorder|
I Iossifov, BJ O’roak, SJ Sanders, M Ronemus, N Krumm, D Levy, ...
Nature 515 (7526), 216-221, 2014
|Transformation of mammalian cells with genes from procaryotes and eucaryotes|
M Wigler, R Sweet, GK Sim, B Wold, A Pellicer, E Lacy, T Maniatis, ...
Cell 16 (4), 777-785, 1979
|Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor|
M Wigler, A Pellicer, S Silverstein, R Axel
Cell 14 (3), 725-731, 1978
|DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells|
M Wigler, A Pellicer, S Silverstein, R Axel, G Urlaub, L Chasin
Proceedings of the National Academy of Sciences 76 (3), 1373-1376, 1979
|The lipid phosphatase activity of PTEN is critical for its tumor supressor function|
MP Myers, I Pass, IH Batty, J Van der Kaay, JP Stolarov, BA Hemmings, ...
Proceedings of the National Academy of Sciences 95 (23), 13513-13518, 1998
|De novo gene disruptions in children on the autistic spectrum|
I Iossifov, M Ronemus, D Levy, Z Wang, I Hakker, J Rosenbaum, ...
Neuron 74 (2), 285-299, 2012
|Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.|
J Field, J Nikawa, D Broek, B MacDonald, L Rodgers, IA Wilson, ...
Molecular and cellular biology 8 (5), 2159-2165, 1988
|In yeast, RAS proteins are controlling elements of adenylate cyclase|
T Toda, I Uno, T Ishikawa, S Powers, T Kataoka, D Broek, S Cameron, ...
Cell 40 (1), 27-36, 1985
|Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach|
L Zender, MS Spector, W Xue, P Flemming, C Cordon-Cardo, J Silke, ...
Cell 125 (7), 1253-1267, 2006
|P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase|
MP Myers, JP Stolarov, C Eng, J Li, SI Wang, MH Wigler, R Parsons, ...
Proceedings of the National Academy of Sciences 94 (17), 9052-9057, 1997
|Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials|
R Axel, MH Wigler, SJ Silverstein
US Patent 4,399,216, 1983
|Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene|
M Alarcón, BS Abrahams, JL Stone, JA Duvall, JV Perederiy, JM Bomar, ...
The American Journal of Human Genetics 82 (1), 150-159, 2008
|The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins|
R Ballester, DA Marchuk, M Boguski, AM Saulino, R Letcher, M Wigler, ...