| CD31− but Not CD31+ Cardiac Side Population Cells Exhibit Functional Cardiomyogenic Differentiation O Pfister, F Mouquet, M Jain, R Summer, M Helmes, A Fine, WS Colucci, ... Circulation research 97 (1), 52-61, 2005 | 648 | 2005 |
| Differential expression of cardiac titin isoforms and modulation of cellular stiffness O Cazorla, A Freiburg, M Helmes, T Centner, M McNabb, Y Wu, ... Circulation research 86 (1), 59-67, 2000 | 502 | 2000 |
| Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes CC Lim, C Zuppinger, X Guo, GM Kuster, M Helmes, HM Eppenberger, ... Journal of Biological Chemistry 279 (9), 8290-8299, 2004 | 355 | 2004 |
| Titin develops restoring force in rat cardiac myocytes M Helmes, K Trombita´ s, H Granzier Circulation research 79 (3), 619-626, 1996 | 295 | 1996 |
| Titin extensibility in situ: entropic elasticity of permanently folded and permanently unfolded molecular segments K Trombitás, M Greaser, S Labeit, JP Jin, M Kellermayer, M Helmes, ... The Journal of cell biology 140 (4), 853-859, 1998 | 283 | 1998 |
| Mechanically driven contour-length adjustment in rat cardiac titin’s unique N2B sequence: titin is an adjustable spring M Helmes, K Trombitas, T Centner, M Kellermayer, S Labeit, WA Linke, ... Circulation research 84 (11), 1339-1352, 1999 | 202 | 1999 |
| Force-length relations in isolated intact cardiomyocytes subjected to dynamic changes in mechanical load G Iribe, M Helmes, P Kohl American Journal of Physiology-Heart and Circulatory Physiology 292 (3 …, 2007 | 187 | 2007 |
| Cardiac microvascular endothelial enhancement of cardiomyocyte function is impaired by inflammation and restored by empagliflozin RP Juni, DWD Kuster, M Goebel, M Helmes, RJP Musters, ... JACC: Basic to Translational Science 4 (5), 575-591, 2019 | 164 | 2019 |
| Titin determines the Frank-Starling relation in early diastole M Helmes, CC Lim, R Liao, A Bharti, L Cui, DB Sawyer The Journal of general physiology 121 (2), 97-110, 2003 | 163 | 2003 |
| Titin elasticity and mechanism of passive force development in rat cardiac myocytes probed by thin-filament extraction H Granzier, M Kellermayer, M Helmes, K Trombitas Biophysical Journal 73 (4), 2043-2053, 1997 | 146 | 1997 |
| Nonuniform elasticity of titin in cardiac myocytes: a study using immunoelectron microscopy and cellular mechanics H Granzier, M Helmes, K Trombitas Biophysical Journal 70 (1), 430-442, 1996 | 133 | 1996 |
| Temporal pixel multiplexing for simultaneous high-speed, high-resolution imaging G Bub, M Tecza, M Helmes, P Lee, P Kohl Nature methods 7 (3), 209-211, 2010 | 118 | 2010 |
| Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells NMP King, M Methawasin, J Nedrud, N Harrell, CS Chung, M Helmes, ... Journal of General Physiology 137 (1), 81-91, 2011 | 84 | 2011 |
| A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility CC Lim, H Yang, M Yang, CK Wang, J Shi, EA Berg, DR Pimentel, ... Biophysical journal 94 (9), 3577-3589, 2008 | 82 | 2008 |
| Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness V Sequeira, A Najafi, M McConnell, ED Fowler, IAE Bollen, RCI Wüst, ... The Journal of physiology 593 (17), 3899-3916, 2015 | 76 | 2015 |
| Mechanical properties of titin isoforms H Granzier, M Helmes, O Cazorla, M McNabb, D Labeit, Y Wu, ... Elastic Filaments of the Cell, 283-304, 2000 | 63 | 2000 |
| Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension ED Fowler, D Benoist, MJ Drinkhill, R Stones, M Helmes, RCI Wüst, ... Journal of molecular and cellular cardiology 86, 1-8, 2015 | 62 | 2015 |
| Mimicking the cardiac cycle in intact cardiomyocytes using diastolic and systolic force clamps; measuring power output M Helmes, A Najafi, BM Palmer, E Breel, N Rijnveld, D Iannuzzi, ... Cardiovascular research 111 (1), 66-73, 2016 | 50 | 2016 |
| Restoring force development by titin/connectin and assessment of Ig domain unfolding N Preetha, W Yiming, M Helmes, F Norio, L Siegfried, H Granzier Journal of Muscle Research & Cell Motility 26, 307-317, 2005 | 46 | 2005 |
| Rapid frequency‐dependent changes in free mitochondrial calcium concentration in rat cardiac myocytes RCI Wüst, M Helmes, JL Martin, TJT van der Wardt, RJP Musters, ... The Journal of Physiology 595 (6), 2001-2019, 2017 | 45 | 2017 |
