MICHELE PAGANO
MICHELE PAGANO
Chair, Department of Biochemistry and Molecular Pharmacology, Ellen and Gerald Ritter Professor of
Verified email at nyumc.org - Homepage
TitleCited byYear
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
M Pagano, SW Tam, AM Theodoras, P Beer-Romero, G Del Sal, V Chau, ...
Science 269 (5224), 682-685, 1995
20531995
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
AC Carrano, E Eytan, A Hershko, M Pagano
Nature cell biology 1 (4), 193, 1999
16341999
Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
V Baldin, J Lukas, MJ Marcote, M Pagano, G Draetta
Genes & development 7 (5), 812-821, 1993
15971993
Cyclin A is required at two points in the human cell cycle.
M Pagano, R Pepperkok, F Verde, W Ansorge, G Draetta
The EMBO journal 11 (3), 961-971, 1992
13761992
Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ...
Nature 416 (6882), 703, 2002
13342002
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
M Loda, B Cukor, SW Tam, P Lavin, M Fiorentinc, GF Draetta, JM Jessup, ...
Nature medicine 3 (2), 231, 1997
12791997
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition.
M Ohtsubo, AM Theodoras, J Schumacher, JM Roberts, M Pagano
Molecular and cellular biology 15 (5), 2612-2624, 1995
12591995
The SCF ubiquitin ligase: insights into a molecular machine
T Cardozo, M Pagano
Nature reviews Molecular cell biology 5 (9), 739, 2004
10202004
Regulation of the cdk inhibitor p27 and its deregulation in cancer
J Slingerland, M Pagano
Journal of cellular physiology 183 (1), 10-17, 2000
8482000
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer
D Frescas, M Pagano
Nature Reviews Cancer 8 (6), 438, 2008
7682008
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation
A Montagnoli, F Fiore, E Eytan, AC Carrano, GF Draetta, A Hershko, ...
Genes & development 13 (9), 1181-1189, 1999
6351999
The F-box protein family
ET Kipreos, M Pagano
Genome biology 1 (5), reviews3002. 1, 2000
6342000
S6K1-and ▀TRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
NV Dorrello, A Peschiaroli, D Guardavaccaro, NH Colburn, NE Sherman, ...
Science 314 (5798), 467-471, 2006
6072006
Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex
BA Schulman, AC Carrano, PD Jeffrey, Z Bowen, ERE Kinnucan, ...
Nature 408 (6810), 381, 2000
5862000
Systematic analysis and nomenclature of mammalian F-box proteins
J Jin, T Cardozo, RC Lovering, SJ Elledge, M Pagano, JW Harper
Genes & development 18 (21), 2573-2580, 2004
5632004
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
V Esposito, A Baldi, A De Luca, AM Groger, M Loda, GG Giordano, ...
Cancer Research 57 (16), 3381-3385, 1997
5571997
The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27
D Ganoth, G Bornstein, TK Ko, B Larsen, M Tyers, M Pagano, A Hershko
Nature cell biology 3 (3), 321, 2001
5132001
Control of the SCFSkp2–Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase
T Bashir, NV Dorrello, V Amador, D Guardavaccaro, M Pagano
Nature 428 (6979), 190, 2004
4962004
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
G Bornstein, J Bloom, D Sitry-Shevah, K Nakayama, M Pagano, ...
Journal of Biological Chemistry 278 (28), 25752-25757, 2003
4792003
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a, b) invasive breast carcinomas
P Tan, B Cady, M Wanner, P Worland, B Cukor, C Magi-Galluzzi, P Lavin, ...
Cancer research 57 (7), 1259-1263, 1997
4791997
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