Frank J. Gonzalez
Frank J. Gonzalez
National Cancer Institute
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The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
DR Nelson, T Kamataki, DJ Waxman, FP Guengerich, RW Estabrook, ...
DNA and cell biology 12 (1), 1-51, 1993
P450 genes: structure, evolution, and regulation
DW Nebert, FJ Gonzalez
Annual review of biochemistry 56 (1), 945-993, 1987
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
S Kersten, J Seydoux, JM Peters, FJ Gonzalez, B Desvergne, W Wahli
The Journal of clinical investigation 103 (11), 1489-1498, 1999
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
CJ Sinal, M Tohkin, M Miyata, JM Ward, G Lambert, FJ Gonzalez
Cell 102 (6), 731-744, 2000
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
SST Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ...
Molecular and cellular biology 15 (6), 3012-3022, 1995
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
H Zhang, M Bosch-Marce, LA Shimoda, YS Tan, JH Baek, JB Wesley, ...
Journal of Biological Chemistry 283 (16), 10892-10903, 2008
The molecular biology of cytochrome P450s
FJ Gonzalez
Pharmacol. Rev. 40, 243-288, 1988
C/EBPα induces adipogenesis through PPARγ: a unified pathway
ED Rosen, CH Hsu, X Wang, S Sakai, MW Freeman, FJ Gonzalez, ...
Genes & development 16 (1), 22-26, 2002
The PPARα–leukotriene B4 pathway to inflammation control
PR Devchand, H Keller, JM Peters, M Vazquez, FJ Gonzalez, W Wahli
Nature 384 (6604), 39-43, 1996
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature
DNA and cell biology 10 (1), 1-14, 1991
Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1
P Delerive, K De Bosscher, S Besnard, WV Berghe, JM Peters, ...
Journal of Biological Chemistry 274 (45), 32048-32054, 1999
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
DW Nebert, TP Dalton, AB Okey, FJ Gonzalez
Journal of biological chemistry 279 (23), 23847-23850, 2004
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
P Fernandez-Salguero, T Pineau, DM Hilbert, T McPhail, SST Lee, ...
Science 268 (5211), 722-726, 1995
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.
S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, ...
Genes & development 10 (1), 60-69, 1996
Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
GP Hayhurst, YH Lee, G Lambert, JM Ward, FJ Gonzalez
Molecular and cellular biology 21 (4), 1393-1403, 2001
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors
L Michalik, J Auwerx, JP Berger, VK Chatterjee, CK Glass, FJ Gonzalez, ...
Pharmacological reviews 58 (4), 726-741, 2006
The P450 gene superfamily: recommended nomenclature
DW Nebert, M Adesnik, MJ Coon, RW Estabrook, FJ Gonzalez, ...
Dna 6 (1), 1-11, 1987
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
Y Zhang, FY Lee, G Barrera, H Lee, C Vales, FJ Gonzalez, TM Willson, ...
Proceedings of the National Academy of Sciences 103 (4), 1006-1011, 2006
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα)
T Aoyama, JM Peters, N Iritani, T Nakajima, K Furihata, T Hashimoto, ...
Journal of Biological Chemistry 273 (10), 5678-5684, 1998
Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity
PM Fernandez-Salguero, DM Hilbert, S Rudikoff, JM Ward, FJ Gonzalez
Toxicology and applied pharmacology 140 (1), 173-179, 1996
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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