Michael Groessl
Michael Groessl
University Hospital Bern
Email verificata su dbmr.unibe.ch
TitoloCitata daAnno
KP1019, a new redox‐active anticancer agent–Preclinical development and results of a clinical phase I study in tumor patients
CG Hartinger, MA Jakupec, S Zorbas‐Seifried, M Groessl, A Egger, ...
Chemistry & biodiversity 5 (10), 2140-2155, 2008
6852008
Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity
Z Adhireksan, GE Davey, P Campomanes, M Groessl, CM Clavel, H Yu, ...
Nature communications 5, 3462, 2014
2172014
Structure−Activity Relationships for NAMI-A-type Complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = Imidazole, Indazole, 1,2,4-Triazole, 4-Amino-1,2,4…
M Groessl, E Reisner, CG Hartinger, R Eichinger, O Semenova, ...
Journal of medicinal chemistry 50 (9), 2185-2193, 2007
2172007
Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity
MG Mendoza-Ferri, CG Hartinger, MA Mendoza, M Groessl, AE Egger, ...
Journal of medicinal chemistry 52 (4), 916-925, 2009
1612009
A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
B Wu, MS Ong, M Groessl, Z Adhireksan, CG Hartinger, PJ Dyson, ...
Chemistry–A European Journal 17 (13), 3562-3566, 2011
1482011
Metal-based inhibition of poly (ADP-ribose) polymerase− the guardian angel of DNA
F Mendes, M Groessl, AA Nazarov, YO Tsybin, G Sava, I Santos, ...
Journal of medicinal chemistry 54 (7), 2196-2206, 2011
1312011
High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids
M Groessl, S Graf, R Knochenmuss
Analyst 140 (20), 6904-6911, 2015
1092015
Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin
M Groessl, O Zava, PJ Dyson
Metallomics 3 (6), 591-599, 2011
1092011
Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum (IV) complexes
MR Reithofer, AK Bytzek, SM Valiahdi, CR Kowol, M Groessl, ...
Journal of inorganic biochemistry 105 (1), 46-51, 2011
1082011
In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate‐based ligands
I Berger, M Hanif, AA Nazarov, CG Hartinger, RO John, ML Kuznetsov, ...
Chemistry–A European Journal 14 (29), 9046-9057, 2008
1082008
Greener synthesis of new ammonium ionic liquids and their potential as extracting agents
D Kogelnig, A Stojanovic, M Galanski, M Groessl, F Jirsa, R Krachler, ...
Tetrahedron Letters 49 (17), 2782-2785, 2008
1072008
Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS
M Groessl, M Terenghi, A Casini, L Elviri, R Lobinski, PJ Dyson
Journal of analytical atomic spectrometry 25 (3), 305-313, 2010
1002010
CZE–ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP
M Groessl, CG Hartinger, PJ Dyson, BK Keppler
Journal of inorganic biochemistry 102 (5-6), 1060-1065, 2008
972008
Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs
CG Hartinger, M Groessl, SM Meier, A Casini, PJ Dyson
Chemical Society Reviews 42 (14), 6186-6199, 2013
952013
Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine
O Brandt, M Mildner, AE Egger, M Groessl, U Rix, M Posch, BK Keppler, ...
Nanomedicine: Nanotechnology, Biology and Medicine 8 (4), 478-488, 2012
952012
Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry
M Groessl, YO Tsybin, CG Hartinger, BK Keppler, PJ Dyson
JBIC Journal of Biological Inorganic Chemistry 15 (5), 677-688, 2010
902010
Capillary electrophoresis hyphenated to inductively coupled plasma‐mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma
M Groessl, CG Hartinger, K Polec‐Pawlak, M Jarosz, BK Keppler
Electrophoresis 29 (10), 2224-2232, 2008
872008
Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold–titanium complexes
M Wenzel, B Bertrand, MJ Eymin, V Comte, JA Harvey, P Richard, ...
Inorganic chemistry 50 (19), 9472-9480, 2011
812011
Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules
M Hanif, AA Nazarov, A Legin, M Groessl, VB Arion, MA Jakupec, ...
Chemical Communications 48 (10), 1475-1477, 2012
762012
Phosphonium and ammonium ionic liquids with aromatic anions: synthesis, properties, and platinum extraction
A Stojanovic, D Kogelnig, L Fischer, S Hann, M Galanski, M Groessl, ...
Australian journal of chemistry 63 (3), 511-524, 2010
752010
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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