Segui
David Tuveson
David Tuveson
Email verificata su cshl.edu
Titolo
Citata da
Citata da
Anno
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
GD Demetri, M Von Mehren, CD Blanke, AD Van den Abbeele, ...
New England Journal of Medicine 347 (7), 472-480, 2002
54832002
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
35172009
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani, EF Petricoin, A Maitra, V Rajapakse, C King, MA Jacobetz, ...
Cancer cell 4 (6), 437-450, 2003
27582003
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
H Joensuu, PJ Roberts, M Sarlomo-Rikala, LC Andersson, ...
New England Journal of Medicine 344 (14), 1052-1056, 2001
27292001
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani, L Wang, AS Multani, C Combs, TB Deramaudt, RH Hruban, ...
Cancer cell 7 (5), 469-483, 2005
26652005
A framework for advancing our understanding of cancer-associated fibroblasts
E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ...
Nature Reviews Cancer 20 (3), 174-186, 2020
24212020
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
22612011
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
21792012
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson, N Willis, K Mercer, RT Bronson, D Crowley, R Montoya, ...
Genes & development 15 (24), 3243-3248, 2001
21422001
Restoration of p53 function leads to tumour regression in vivo
A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ...
Nature 445 (7128), 661-665, 2007
21042007
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
D Öhlund, A Handly-Santana, G Biffi, E Elyada, AS Almeida, ...
Journal of Experimental Medicine 214 (3), 579-596, 2017
19092017
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
18922015
Pancreatic cancer
J Kleeff, M Korc, M Apte, C La Vecchia, CD Johnson, AV Biankin, ...
Nature reviews Disease primers 2 (1), 1-22, 2016
18302016
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
C Feig, JO Jones, M Kraman, RJB Wells, A Deonarine, DS Chan, ...
Proceedings of the National Academy of Sciences 110 (50), 20212-20217, 2013
17792013
Transcriptional regulation by Nrf2
C Tonelli, IIC Chio, DA Tuveson
Antioxidants & redox signaling 29 (17), 1727-1745, 2018
16542018
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
KP Olive, DA Tuveson, ZC Ruhe, B Yin, NA Willis, RT Bronson, D Crowley, ...
Cell 119 (6), 847-860, 2004
14782004
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ...
Nature 469 (7331), 539-542, 2011
13902011
The pancreas cancer microenvironment
C Feig, A Gopinathan, A Neesse, DS Chan, N Cook, DA Tuveson
Clinical cancer research 18 (16), 4266-4276, 2012
13832012
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
L Johnson, K Mercer, D Greenbaum, RT Bronson, D Crowley, ...
Nature 410 (6832), 1111-1116, 2001
13402001
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts
E Elyada, M Bolisetty, P Laise, WF Flynn, ET Courtois, RA Burkhart, ...
Cancer discovery 9 (8), 1102-1123, 2019
12992019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20