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Kailin Yang, MD, PhD
Kailin Yang, MD, PhD
Taussig Cancer Center, Cleveland Clinic
Verified email at ccf.org
Title
Cited by
Cited by
Year
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ...
Nature 582 (7811), 289-293, 2020
39192020
Design of wide-spectrum inhibitors targeting coronavirus main proteases
H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ...
PLoS biology 3 (10), e324, 2005
7472005
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur
Z Jin, Y Zhao, Y Sun, B Zhang, H Wang, Y Wu, Y Zhu, C Zhu, T Hu, X Du, ...
Nature structural & molecular biology 27 (6), 529-532, 2020
3932020
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
MA Cohn, P Kowal, K Yang, W Haas, TT Huang, SP Gygi, AD D'Andrea
Molecular cell 28 (5), 786-797, 2007
3822007
Mitochondrial control by DRP1 in brain tumor initiating cells
Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ...
Nature neuroscience 18 (4), 501-510, 2015
3642015
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction
X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ...
Journal of molecular biology 366 (3), 965-975, 2007
2412007
Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression
X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ...
Cell stem cell 22 (4), 514-528. e5, 2018
2182018
Structure of main protease from human coronavirus NL63: insights for wide spectrum anti-coronavirus drug design
F Wang, C Chen, W Tan, K Yang, H Yang
Scientific reports 6 (1), 22677, 2016
1902016
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ...
Nature neuroscience 20 (5), 661-673, 2017
1722017
Regulation of Rev1 by the Fanconi anemia core complex
H Kim, K Yang, D Dejsuphong, AD D'Andrea
Nature structural & molecular biology 19 (2), 164-170, 2012
1692012
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response
M Huang, JM Kim, B Shiotani, K Yang, L Zou, AD D'Andrea
Molecular cell 39 (2), 259-268, 2010
1662010
Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332
Y Zhao, C Fang, Q Zhang, R Zhang, X Zhao, Y Duan, H Wang, Y Zhu, ...
Protein & cell 13 (9), 689-693, 2022
1652022
Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1
K Lee, K Yang, MA Cohn, N Sikdar, AD D'Andrea, K Myung
Journal of biological chemistry 285 (14), 10362-10369, 2010
1492010
The USP1/UAF1 complex promotes double-strand break repair through homologous recombination
J Murai, K Yang, D Dejsuphong, K Hirota, S Takeda, AD D'Andrea
Molecular and cellular biology, 2011
1432011
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
X Fang, W Zhou, Q Wu, Z Huang, Y Shi, K Yang, C Chen, Q Xie, SC Mack, ...
Journal of Experimental Medicine 214 (1), 245-267, 2017
1352017
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells
X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ...
Science translational medicine 11 (504), eaau4972, 2019
1252019
MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells
X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ...
Cancer research 77 (18), 4947-4960, 2017
1082017
Regulation of the Fanconi anemia pathway by a SUMO-like delivery network
K Yang, GL Moldovan, P Vinciguerra, J Murai, S Takeda, AD D'Andrea
Genes & development 25 (17), 1847-1858, 2011
1072011
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
Y Zhao, X Du, Y Duan, X Pan, Y Sun, T You, L Han, Z Jin, W Shang, J Yu, ...
Protein & cell 12 (11), 877-888, 2021
1012021
Recent progress in the drug development targeting SARS-CoV-2 main protease as treatment for COVID-19
W Cui, K Yang, H Yang
Frontiers in molecular biosciences 7, 616341, 2020
972020
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