Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia CN Hahn, CE Chong, CL Carmichael, EJ Wilkins, PJ Brautigan, XC Li, ... Nature genetics 43 (10), 1012, 2011 | 497 | 2011 |
A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia S Shah, KA Schrader, E Waanders, AE Timms, J Vijai, C Miething, ... Nature genetics 45 (10), 1226-1231, 2013 | 252 | 2013 |
Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature J Kazenwadel, GA Secker, YJ Liu, JA Rosenfeld, RS Wildin, ... Blood 119 (5), 1283-1291, 2012 | 230 | 2012 |
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1–dependent activation of PI-3K/Akt and regulation of Bcl-2 family members V Limaye, X Li, C Hahn, P Xia, MC Berndt, MA Vadas, JR Gamble Blood 105 (8), 3169-3177, 2005 | 184 | 2005 |
Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid β-galactosidase CN Hahn, M del Pilar Martin, M Schröder, MT Vanier, K Suzuki, Y Hara, ... Human molecular genetics 6 (2), 205-211, 1997 | 146 | 1997 |
PPARγ agonists ameliorate endothelial cell activation via inhibition of diacylglycerol–protein kinase C signaling pathway: role of diacylglycerol kinase E Verrier, L Wang, C Wadham, N Albanese, C Hahn, JR Gamble, ... Circulation research 94 (11), 1515-1522, 2004 | 128 | 2004 |
Transcriptional synergism between vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) promoter DM Kerry, PP Dwivedi, CN Hahn, HA Morris, JL Omdahl, BK May Journal of Biological Chemistry 271 (47), 29715-29721, 1996 | 127 | 1996 |
Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies M Lewinsohn, AL Brown, LM Weinel, C Phung, G Rafidi, MK Lee, ... Blood 127 (8), 1017-1023, 2016 | 119 | 2016 |
GATA2 is required for lymphatic vessel valve development and maintenance J Kazenwadel, KL Betterman, CE Chong, PH Stokes, YK Lee, GA Secker, ... The Journal of clinical investigation 125 (8), 2979-2994, 2015 | 118 | 2015 |
Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects JR Gamble, P Xia, CN Hahn, JJ Drew, CJ Drogemuller, D Brown, ... International journal of cancer 118 (10), 2412-2420, 2006 | 94 | 2006 |
Basal and angiopoietin-1–mediated endothelial permeability is regulated by sphingosine kinase-1 X Li, M Stankovic, CS Bonder, CN Hahn, M Parsons, SM Pitson, P Xia, ... Blood, The Journal of the American Society of Hematology 111 (7), 3489-3497, 2008 | 93 | 2008 |
Systemic and neurologic abnormalities distinguish the lysosomal disorders sialidosis and galactosialidosis in mice N de Geest, E Bonten, L Mann, J de Sousa-Hitzler, C Hahn, A d'Azzo Human molecular genetics 11 (12), 1455-1464, 2002 | 93 | 2002 |
Ozz-E3, a muscle-specific ubiquitin ligase, regulates β-catenin degradation during myogenesis T Nastasi, A Bongiovanni, Y Campos, L Mann, JN Toy, J Bostrom, ... Developmental cell 6 (2), 269-282, 2004 | 92 | 2004 |
ARMC5 mutations are common in familial bilateral macronodular adrenal hyperplasia L Gagliardi, AW Schreiber, CN Hahn, J Feng, T Cranston, H Boon, C Hotu, ... The Journal of Clinical Endocrinology & Metabolism 99 (9), E1784-E1792, 2014 | 86 | 2014 |
Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development N Young, CN Hahn, A Poh, C Dong, D Wilhelm, J Olsson, GEO Muscat, ... Journal of the National Cancer Institute 98 (15), 1060-1067, 2006 | 85 | 2006 |
Role of protein kinase Cζ in thrombin-induced endothelial permeability changes: inhibition by angiopoietin-1 X Li, CN Hahn, M Parsons, J Drew, MA Vadas, JR Gamble Blood 104 (6), 1716-1724, 2004 | 85 | 2004 |
Novel RUNX1 mutations in familial platelet disorder with enhanced risk for acute myeloid leukemia: clues for improved identification of the FPD/AML syndrome MCJ Jongmans, RP Kuiper, CL Carmichael, EJ Wilkins, N Dors, ... Leukemia 24 (1), 242-246, 2010 | 82 | 2010 |
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability LS Nguyen, L Jolly, C Shoubridge, WK Chan, L Huang, F Laumonnier, ... Molecular psychiatry 17 (11), 1103-1115, 2012 | 78 | 2012 |
Identification of a vitamin D responsive element in the promoter of the rat cytochrome P450 24 gene CN Hahn, DM Kerry, JL Omdahl, BK May Nucleic acids research 22 (12), 2410-2416, 1994 | 69 | 1994 |
Transcriptional regulation of the chicken CYP2H1 gene. Localization of a phenobarbital-responsive enhancer domain. CN Hahn, AJ Hansen, BK May Journal of Biological Chemistry 266 (26), 17031-17039, 1991 | 61 | 1991 |