Marian Beekman
Marian Beekman
Senior Scientist, Molecular Epidemiology, LUMC
Email verificata su lumc.nl
Titolo
Citata da
Citata da
Anno
Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197-206, 2015
26042015
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173, 2014
14602014
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
8912015
Identification of seven loci affecting mean telomere length and their association with disease
V Codd, CP Nelson, E Albrecht, M Mangino, J Deelen, JL Buxton, ...
Nature genetics 45 (4), 422-427, 2013
6462013
Whole-genome sequence variation, population structure and demographic history of the Dutch population
LC Francioli, A Menelaou, SL Pulit, F Van Dijk, PF Palamara, CC Elbers, ...
Nature genetics 46 (8), 818, 2014
5002014
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ...
PLoS Genet 8 (3), e1002607, 2012
3932012
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ...
Nature 541 (7635), 81-86, 2017
3882017
Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study
M Schoenmaker, AJM de Craen, PHEM de Meijer, M Beekman, GJ Blauw, ...
European Journal of Human Genetics 14 (1), 79-84, 2006
3502006
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
L Broer, V Codd, DR Nyholt, J Deelen, M Mangino, G Willemsen, ...
European journal of human genetics 21 (10), 1163-1168, 2013
3122013
Reduced insulin/IGF‐1 signalling and human longevity
D Van Heemst, M Beekman, SP Mooijaart, BT Heijmans, BW Brandt, ...
Aging cell 4 (2), 79-85, 2005
3022005
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
J Kettunen, A Demirkan, P Würtz, HHM Draisma, T Haller, R Rawal, ...
Nature communications 7 (1), 1-9, 2016
2632016
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ...
Aging cell 10 (4), 686-698, 2011
2632011
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
G Lauc, JE Huffman, M Pučić, L Zgaga, B Adamczyk, A Mužinić, ...
PLoS Genet 9 (1), e1003225, 2013
2482013
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study
RGJ Westendorp, D Van Heemst, MP Rozing, M Frölich, SP Mooijaart, ...
Journal of the American Geriatrics Society 57 (9), 1634-1637, 2009
2442009
Variation in the human TP53 gene affects old age survival and cancer mortality
D van Heemst, SP Mooijaart, M Beekman, J Schreuder, AJM de Craen, ...
Experimental gerontology 40 (1-2), 11-15, 2005
2252005
The impact of low-frequency and rare variants on lipid levels
I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, ...
Nature genetics 47 (6), 589-597, 2015
2202015
The Genome of the Netherlands: design, and project goals
DI Boomsma, C Wijmenga, EP Slagboom, MA Swertz, LC Karssen, ...
European Journal of Human Genetics 22 (2), 221-227, 2014
2112014
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
2072017
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
J Deelen, M Beekman, HW Uh, L Broer, KL Ayers, Q Tan, Y Kamatani, ...
Human molecular genetics 23 (16), 4420-4432, 2014
2002014
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
1932017
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