Regulation of mitochondrial morphology and function by stearoylation of TFR1 D Senyilmaz, S Virtue, X Xu, CY Tan, JL Griffin, AK Miller, A Vidal-Puig, ... Nature 525 (7567), 124-128, 2015 | 230 | 2015 |
Total synthesis of (−)-heptemerone B and (−)-guanacastepene E AK Miller, CC Hughes, JJ Kennedy-Smith, SN Gradl, D Trauner Journal of the American Chemical Society 128 (51), 17057-17062, 2006 | 156 | 2006 |
Elevated levels of the reactive metabolite methylglyoxal recapitulate progression of type 2 diabetes A Moraru, J Wiederstein, D Pfaff, T Fleming, AK Miller, P Nawroth, ... Cell metabolism 27 (4), 926-934. e8, 2018 | 151 | 2018 |
Synthesis of arylpiperazines via palladium-catalyzed aromatic amination reaction with unprotected piperazines SH Zhao, AK Miller, J Berger, LA Flippin Tetrahedron Letters 37 (26), 4463-4466, 1996 | 125 | 1996 |
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals U Barayeu, D Schilling, M Eid, TN Xavier da Silva, L Schlicker, N Mitreska, ... Nature chemical biology 19 (1), 28-37, 2023 | 119 | 2023 |
Aryl pyrimidine derivatives J Berger, LA Flippin, R Greenhouse, S Jaime-Figueroa, Y Liu, AK Miller, ... US Patent 5,863,924, 1999 | 113* | 1999 |
D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma S Pusch, L Schweizer, AC Beck, JM Lehmler, S Weissert, J Balss, ... Acta neuropathologica communications 2, 1-10, 2014 | 103 | 2014 |
Selective inhibition of histone deacetylase 10: hydrogen bonding to the gatekeeper residue is implicated M Géraldy, M Morgen, P Sehr, RR Steimbach, D Moi, J Ridinger, I Oehme, ... Journal of medicinal Chemistry 62 (9), 4426-4443, 2019 | 87 | 2019 |
An electrochemical approach to the guanacastepenes CC Hughes, AK Miller, D Trauner Organic Letters 7 (16), 3425-3428, 2005 | 81 | 2005 |
Mining the tetraene manifold: total synthesis of complex pyrones from Placobranchus ocellatus AK Miller, D Trauner Angewandte Chemie-International Edition 44 (29), 4602-4606, 2005 | 75 | 2005 |
Biomimetic synthesis of elysiapyrones A and B JE Barbarow, AK Miller, D Trauner Organic Letters 7 (14), 2901-2903, 2005 | 60 | 2005 |
Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target S Lechner, MIP Malgapo, C Grätz, RR Steimbach, A Baron, P Rüther, ... Nature chemical biology 18 (8), 812-820, 2022 | 58 | 2022 |
Development of novel Lewis acid catalyzed cycloisomerizations: synthesis of bicyclo [3.1. 0] hexenes and cyclopentenones AK Miller, MR Banghart, CM Beaudry, JM Suh, D Trauner Tetrahedron 59 (45), 8919-8930, 2003 | 55 | 2003 |
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance J Ridinger, E Koeneke, FR Kolbinger, K Koerholz, S Mahboobi, L Hellweg, ... Scientific reports 8 (1), 10039, 2018 | 54 | 2018 |
Total synthesis of (±)-photodeoxytridachione through a Lewis acid catalyzed cyclization AK Miller, D Trauner Angewandte Chemie-International Edition 42 (5), 549-552, 2003 | 48 | 2003 |
Benzothiazole derivatives with activity as adenosine receptor ligands A Alanine, A Flohr, AK Miller, RD Norcross, C Riemer US Patent 6,521,754, 2003 | 43 | 2003 |
Systematic screening for venous thromboembolic events in COVID-19 pneumonia G Grandmaison, A Andrey, D Périard, RP Engelberger, G Carrel, S Doll, ... TH Open 4 (02), e113-e115, 2020 | 41 | 2020 |
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines FR Kolbinger, E Koeneke, J Ridinger, T Heimburg, M Müller, T Bayer, ... Archives of Toxicology 92, 2649-2664, 2018 | 41 | 2018 |
Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development J Lohbeck, AK Miller Bioorganic & Medicinal Chemistry Letters 26 (21), 5260-5262, 2016 | 41 | 2016 |
Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry R Longuespée, AK Wefers, E De Vita, AK Miller, DE Reuss, W Wick, ... Acta neuropathologica communications 6, 1-9, 2018 | 38 | 2018 |