| ABT-888, an orally active poly (ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models CK Donawho, Y Luo, Y Luo, TD Penning, JL Bauch, JJ Bouska, ... Clinical cancer research 13 (9), 2728-2737, 2007 | 900 | 2007 |
| A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat MF Jarvis, EC Burgard, S McGaraughty, P Honore, K Lynch, TJ Brennan, ... Proceedings of the National Academy of Sciences 99 (26), 17179-17184, 2002 | 558 | 2002 |
| The utility of hERG and repolarization assays in evaluating delayed cardiac repolarization: influence of multi-channel block RL Martin, JS McDermott, HJ Salmen, J Palmatier, BF Cox, GA Gintant Journal of cardiovascular pharmacology 43 (3), 369-379, 2004 | 211 | 2004 |
| The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis GA Gintant, JT Limberis, JS McDermott, CD Wegner, BF Cox Journal of cardiovascular pharmacology 37 (5), 607-618, 2001 | 200 | 2001 |
| The [3H] dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of … GJ Diaz, K Daniell, ST Leitza, RL Martin, Z Su, JS McDermott, BF Cox, ... Journal of pharmacological and toxicological methods 50 (3), 187-199, 2004 | 177 | 2004 |
| Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema RM Fryer, J Segreti, PN Banfor, DL Widomski, BJ Backes, CW Lin, ... British journal of pharmacology 153 (5), 947-955, 2008 | 158 | 2008 |
| Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: involvement of potassium channels. LA Merkel, RW Lappe, LM Rivera, BF Cox, MH Perrone Journal of Pharmacology and Experimental Therapeutics 260 (2), 437-443, 1992 | 132 | 1992 |
| Neural and humoral mechanisms of angiotensin-dependent hypertension BF Cox, VS Bishop American Journal of Physiology-Heart and Circulatory Physiology 261 (4 …, 1991 | 122 | 1991 |
| ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl) pyrido [2, 3-d] pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti … EA Kowaluk, J Mikusa, CT Wismer, CZ Zhu, E Schweitzer, JJ Lynch, ... Journal of Pharmacology and Experimental Therapeutics 295 (3), 1165-1174, 2000 | 114 | 2000 |
| Cardioprotective effects of the novel adenosine A1/A2 receptor agonist AMP 579 in a porcine model of myocardial infarction GJ Smits, M McVey, BF Cox, MH Perrone, KL Clark Journal of Pharmacology and Experimental Therapeutics 286 (2), 611-618, 1998 | 110 | 1998 |
| Direct evidence for the role of neuropeptide Y in sympathetic nerve stimulation-induced vasoconstriction S Han, CL Yang, X Chen, L Naes, BF Cox, T Westfall American Journal of Physiology-Heart and Circulatory Physiology 274 (1 …, 1998 | 105 | 1998 |
| Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI CL Chin, AE Tovcimak, VP Hradil, TR Seifert, PR Hollingsworth, ... British journal of pharmacology 153 (2), 367-379, 2008 | 93 | 2008 |
| Potentiation of temozolomide cytotoxicity by poly (ADP) ribose polymerase inhibitor ABT-888 requires a conversion of single-stranded DNA damages to double-stranded DNA breaks X Liu, Y Shi, R Guan, C Donawho, Y Luo, J Palma, G Zhu, EF Johnson, ... Molecular Cancer Research 6 (10), 1621-1629, 2008 | 92 | 2008 |
| ABT‐089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders LE Rueter, DJ Anderson, CA Briggs, DL Donnelly‐Roberts, GA Gintant, ... CNS drug reviews 10 (2), 167-182, 2004 | 89 | 2004 |
| Utility of hERG assays as surrogate markers of delayed cardiac repolarization and QT safety GA Gintant, Z Su, RL Martin, BF Cox Toxicologic pathology 34 (1), 81-90, 2006 | 87 | 2006 |
| Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in … PN Banfor, LC Preusser, TJ Campbell, KC Marsh, JS Polakowski, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (1 …, 2008 | 84 | 2008 |
| Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats NL Lubbers, JS Polakowski, CD Wegner, SE Burke, GJ Diaz, KM Daniell, ... European journal of pharmacology 435 (1), 79-83, 2002 | 73 | 2002 |
| BP 897, a Selective Dopamine D3 Receptor Ligand with Therapeutic Potential for the Treatment of Cocaine‐Addiction FJ Garcia‐Ladona, BF Cox CNS drug reviews 9 (2), 141-158, 2003 | 72 | 2003 |
| Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster AJ King, JA Segreti, KJ Larson, AJ Souers, PR Kym, RM Reilly, G Zhao, ... Journal of Pharmacology and Experimental Therapeutics 330 (2), 526-531, 2009 | 71 | 2009 |
| Electrophysiologic characterization of a novel hERG channel activator Z Su, J Limberis, A Souers, P Kym, A Mikhail, K Houseman, G Diaz, X Liu, ... Biochemical pharmacology 77 (8), 1383-1390, 2009 | 68 | 2009 |
